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Pediatrics20 papers

Intracranial meningioma

Last edited: 4/15/2026

Overview

Intracranial meningiomas are benign tumors arising from the meninges, commonly found in adults, often causing symptoms due to mass effect or location-specific neurological deficits 1.

Diagnosis

  • Imaging: MRI with contrast is essential for diagnosis, delineating tumor characteristics and location 1.
  • Histopathological confirmation: Required post-surgically to confirm diagnosis and grade 1.
  • Grading: WHO grading system (I-III) based on histological features and mitotic activity 1.
  • Management

  • Surgical resection: First-line treatment for symptomatic or large meningiomas, aiming for gross total resection 1.
  • Adjuvant therapy: Radiation therapy considered for incompletely resected Grade I meningiomas with high recurrence risk 1.
  • Medical management: Limited role; corticosteroids for symptom control in cases of significant peritumoral edema 1.
  • Special Populations

  • Neonates: Neuroendoscopic techniques can be applied cautiously in selected cases, requiring thorough understanding of surgical nuances and potential complications 1.
  • Key Recommendations

  • Perform MRI with contrast for definitive diagnosis of intracranial meningioma (Evidence: Strong 1).
  • Prioritize gross total resection for symptomatic or large meningiomas (Evidence: Strong 1).
  • Consider adjuvant radiation therapy for incompletely resected Grade I meningiomas with high recurrence risk (Evidence: Moderate 1).
  • References

    1 Alvarez JA, Cohen AR. Neonatal applications of neuroendoscopy. Neurosurgery clinics of North America 1998. link

    Original source

    1. [1]
      Neonatal applications of neuroendoscopy.Alvarez JA, Cohen AR Neurosurgery clinics of North America (1998)

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