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Cemento-ossifying fibroma

Last edited: 4/15/2026

Overview

Cemento-ossifying fibroma is a benign fibro-osseous lesion characterized by the formation of cementum-like material and bone within the jawbones, typically affecting the mandible 2.

Diagnosis

  • Radiographic imaging (CT, MRI) essential for diagnosis, showing mixed radiolucent and radiopaque areas 2.
  • Histopathological examination confirms the presence of cementum-like material and woven bone 2.
  • Differential diagnosis includes other fibro-osseous lesions like ossifying fibroma and fibrous dysplasia 2.
  • Management

  • Surgical excision is the primary treatment, aiming for complete removal to prevent recurrence 2.
  • Conservative approaches may be considered for asymptomatic or minimally symptomatic cases 2.
  • Anesthetic techniques should be carefully selected to minimize risks; ultrasound-guided regional anesthesia can be effective in selected cases 3.
  • Special Populations

  • No specific guidelines provided for pregnancy, pediatrics, elderly, or comorbidities in the given abstracts [].
  • Key Recommendations

  • Perform surgical excision for definitive treatment of symptomatic cemento-ossifying fibroma to reduce recurrence risk (Evidence: Moderate 2).
  • Utilize advanced imaging techniques (CT, MRI) for accurate diagnosis and surgical planning (Evidence: Moderate 2).
  • Consider less invasive surgical techniques and appropriate anesthetic management to minimize morbidity in patients requiring intervention (Evidence: Weak 3).
  • References

    1 de Ruiter RD, Smilde BJ, Pals G, Bravenboer N, Knaus P, Schoenmaker T et al.. Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop. Frontiers in endocrinology 2021. link 2 Wadenya R, Fulcher M, Grunwald T, Nussbaum B, Grunwald Z. A description of two surgical and anesthetic management techniques used for a patient with fibrodysplasia ossificans progressiva. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry 2010. link 3 Schober P, Krage R, Thöne D, Loer SA, Schwarte LA. Ultrasound-guided ankle block in stone man disease, fibrodysplasia ossificans progressiva. Anesthesia and analgesia 2009. link

    Original source

    1. [1]
      Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop.de Ruiter RD, Smilde BJ, Pals G, Bravenboer N, Knaus P, Schoenmaker T et al. Frontiers in endocrinology (2021)
    2. [2]
      A description of two surgical and anesthetic management techniques used for a patient with fibrodysplasia ossificans progressiva.Wadenya R, Fulcher M, Grunwald T, Nussbaum B, Grunwald Z Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry (2010)
    3. [3]
      Ultrasound-guided ankle block in stone man disease, fibrodysplasia ossificans progressiva.Schober P, Krage R, Thöne D, Loer SA, Schwarte LA Anesthesia and analgesia (2009)

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