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Musculoskeletal171 papers

Nonunion of fracture

Last edited: 4/14/2026

Overview

Nonunion of fractures occurs when a broken bone fails to heal within the expected timeframe despite adequate treatment, leading to persistent pain, deformity, and functional impairment 4.

Diagnosis

  • Clinical Presentation: Persistent pain, swelling, and limited range of motion 4.
  • Imaging: Radiographs showing lack of bridging callus formation, CT or MRI for detailed assessment 4.
  • Grading: Specific classifications exist for scaphoid (e.g., Herbert classification), acromion/scapular spine, and coracoid fractures, aiding in diagnosis and treatment planning 123.
  • Management

  • First-Line Treatments:
  • - Scaphoid Nonunion: Arthroscopic intervention shows high union rates and satisfactory outcomes 1. - Long Bone Nonunion: Conventional surgical techniques such as bone grafting, internal fixation, and compression methods 4.
  • Adjunctive Treatments:
  • - Biological Augmentation: Use of autografts, allografts, or bioabsorbable materials to enhance healing 4. - Infection Management: Addressing any underlying infection with appropriate antibiotics and surgical debridement if necessary 4.

    Special Populations

  • Comorbidities: Seizure disorders and renal osteodystrophy can predispose to coracoid process nonunion 3.
  • No Specific Guidance: Limited evidence directly addressing management in pregnancy, pediatrics, or elderly populations 12345.
  • Key Recommendations

  • Arthroscopic Management for Scaphoid Nonunion: Consider arthroscopic intervention for achieving bone union and improved clinical outcomes 1 (Evidence: Moderate).
  • Surgical Techniques for Long Bone Nonunion: Employ conventional surgical techniques including bone grafting and internal fixation for effective management 4 (Evidence: Strong).
  • Early Diagnosis and Classification: Utilize appropriate imaging and classification systems (e.g., Ogawa for coracoid, Herbert for scaphoid) to guide treatment decisions 123 (Evidence: Moderate).
  • References

    1 Basso MA, Smeraglia F, Ocampos-Hernandez M, Balato G, Bernasconi A, Corella-Montoya F. Scaphoid fracture non-union: a systematic review of the arthroscopic management. Acta bio-medica : Atenei Parmensis 2023. link 2 Ogawa K, Matsumura N, Yoshida A, Inokuchi W. Nonunion of the so-called acromion: a systematic review with consideration of the terminology. Archives of orthopaedic and trauma surgery 2023. link 3 Ogawa K, Matsumura N, Yoshida A. Nonunion of the coracoid process: a systematic review. Archives of orthopaedic and trauma surgery 2021. link 4 Nicholson JA, Makaram N, Simpson A, Keating JF. Fracture nonunion in long bones: A literature review of risk factors and surgical management. Injury 2021. link 5 Freeman BH, Hay EL. Nonunion of the capitate: a case report. The Journal of hand surgery 1985. link80102-7)

    Original source

    1. [1]
      Scaphoid fracture non-union: a systematic review of the arthroscopic management.Basso MA, Smeraglia F, Ocampos-Hernandez M, Balato G, Bernasconi A, Corella-Montoya F Acta bio-medica : Atenei Parmensis (2023)
    2. [2]
      Nonunion of the so-called acromion: a systematic review with consideration of the terminology.Ogawa K, Matsumura N, Yoshida A, Inokuchi W Archives of orthopaedic and trauma surgery (2023)
    3. [3]
      Nonunion of the coracoid process: a systematic review.Ogawa K, Matsumura N, Yoshida A Archives of orthopaedic and trauma surgery (2021)
    4. [4]
      Fracture nonunion in long bones: A literature review of risk factors and surgical management.Nicholson JA, Makaram N, Simpson A, Keating JF Injury (2021)
    5. [5]
      Nonunion of the capitate: a case report.Freeman BH, Hay EL The Journal of hand surgery (1985)

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