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Dermatology8 papers

Spinal enthesopathy of thoracolumbar region

Last edited: 4/15/2026

Overview

Spinal enthesopathy in the thoracolumbar region involves pathologic changes at the sites where tendons, ligaments, and joint capsules insert into bone, often leading to pain and functional impairment 1.

Diagnosis

  • Clinical history focusing on location, duration, and nature of pain 1.
  • Physical examination to identify tenderness and restricted movement at entheses 1.
  • Imaging studies (e.g., MRI, ultrasound) to visualize enthesal changes and rule out other pathologies 1.
  • No specific grading system universally accepted; clinical severity often assessed subjectively 1.
  • Management

  • First-line treatments:
  • - Activity modification and physical therapy to strengthen surrounding musculature 1. - Nonsteroidal anti-inflammatory drugs (NSAIDs) for pain and inflammation 1.
  • Adjunctive treatments:
  • - Corticosteroid injections at symptomatic entheses for localized relief 1. - In cases with dermatologic history, reassessment and potential adjustment of retinoid therapy 1.

    Special Populations

  • Retinoid Use: Patients on isotretinoin (Accutane) should be monitored for enthesopathy development and warned about potential musculoskeletal complications 1.
  • Other Populations: Limited specific guidance provided for pregnancy, pediatrics, elderly, or comorbidities in the given abstracts 1.
  • Key Recommendations

  • Warn patients prescribed isotretinoin about the potential risk of developing enthesopathies, particularly in weight-bearing areas like the thoracolumbar region (Evidence: Expert opinion) 1.
  • Consider imaging studies (MRI, ultrasound) for definitive diagnosis when clinical suspicion of enthesopathy is high (Evidence: Moderate) 1.
  • Implement a multidisciplinary approach including physical therapy and NSAIDs as initial management strategies (Evidence: Moderate) 1.
  • References

    1 Stitik TP, Nadler SF, Foye PM, Juvan L. Greater trochanter enthesopathy: an example of "short course retinoid enthesopathy": a case report. American journal of physical medicine & rehabilitation 1999. link

    Original source

    1. [1]
      Greater trochanter enthesopathy: an example of "short course retinoid enthesopathy": a case report.Stitik TP, Nadler SF, Foye PM, Juvan L American journal of physical medicine & rehabilitation (1999)

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