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Pharyngeal hemorrhage

Last edited: 4/22/2026

Overview

Pharyngeal hemorrhage refers to significant bleeding from the pharyngeal region, often complicating surgical procedures or arising from specific etiologies such as vascular anomalies or thorium dioxide exposure. 12

Diagnosis

  • Clinical Presentation: Symptoms include severe throat pain, dysphagia, and hematemesis.
  • Imaging Techniques:
  • - Computed tomography (CT) scans - Three-dimensional time-of-flight magnetic resonance angiogram (MRA) - Doppler ultrasonography 1
  • Specific Anomalies: Identification of bulging internal carotid artery anomalies in the pharyngeal wall 1
  • Histopathological Evaluation: In cases involving granulomas or necrosis, biopsy may be necessary 2
  • Management

  • Surgical Intervention:
  • - Repair or transposition of injured internal carotid artery 1 - Radical neck dissection with caution due to potential weakened carotid artery 2
  • Hemostatic Agents:
  • - Use of topical or systemic agents to achieve hemostasis (specific agents not detailed)
  • Radical Debridement: For severe cases, extensive debridement including laryngopharyngectomy may be required 2
  • Infection Control: Aggressive management of infections to prevent necrosis and further hemorrhage 2
  • Special Populations

  • Radiation-Induced Complications: Elderly patients with history of thorium dioxide exposure may face increased risk of severe hemorrhage 2
  • Comorbidities: Presence of weakened carotid arteries due to prior radiation exposure complicates surgical management 2
  • Key Recommendations

  • Preoperative imaging with CT, MRA, and Doppler ultrasonography is crucial to identify internal carotid artery anomalies in pharyngeal surgery to mitigate bleeding risk (Evidence: Moderate) 1
  • Exercise extreme caution during radical neck dissection in patients with a history of thorium dioxide exposure due to potential carotid artery weakness (Evidence: Weak) 2
  • Aggressive surgical debridement and infection control are essential in managing thorium-dioxide-induced pharyngeal hemorrhage to prevent life-threatening complications (Evidence: Expert opinion) 2
  • References

    1 Galletti B, Bucolo S, Abbate G, Calabrese G, Romano G, Quattrocchi C et al.. Internal carotid artery transposition as risk factor in pharyngeal surgery. The Laryngoscope 2002. link 2 Stanley RB. Thorium-dioxide--induced pharyngeal hemorrhage. American journal of otolaryngology 1983. link80059-3)

    Original source

    1. [1]
      Internal carotid artery transposition as risk factor in pharyngeal surgery.Galletti B, Bucolo S, Abbate G, Calabrese G, Romano G, Quattrocchi C et al. The Laryngoscope (2002)
    2. [2]
      Thorium-dioxide--induced pharyngeal hemorrhage.Stanley RB American journal of otolaryngology (1983)

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