Overview
Infections caused by multi-drug resistant (MDR) bacteria, particularly bloodstream infections (BSI), are a critical public health concern, encompassing pathogens such as carbapenem-resistant Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae, and Escherichia coli, alongside third-generation cephalosporin-resistant E. coli and K. pneumoniae, vancomycin-resistant Enterococcus faecium, and methicillin-resistant Staphylococcus aureus 1. Accurate incidence data and frequency measures of antimicrobial resistance for these key bacteria are essential for prioritizing healthcare investments and guiding the discovery of new therapies 1.References
1 Pezzani MD, Arieti F, Rajendran NB, Barana B, Cappelli E, De Rui ME et al.. Frequency of bloodstream infections caused by six key antibiotic-resistant pathogens for prioritization of research and discovery of new therapies in Europe: a systematic review. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2024. link