Pathophysiology
Among the isolates, 16 (53%) were positive for the class 1 integrase gene and carried the aadA2 resistance gene, highlighting the potential for antibiotic resistance in nosocomial infections [PMID:17803751].
Epidemiology
Among 406 pediatric burns treated with skin grafts between 2006 and 2011, 7% developed burns impetigo [PMID:24823337].
This study identified that 53% of Staphylococcus aureus isolates from both the environment and surgical patients in a Chinese hospital harbored class 1 integrons, indicating potential nosocomial transmission [PMID:17803751].
Management
In pediatric burn patients treated with skin grafts, oral antibiotics plus topical steroids resulted in the shortest mean time to complete healing (13.5 days) compared to other management strategies [PMID:24823337].
The presence of multidrug-resistant S. aureus strains, including those with class 1 integrons, in both patient and environmental samples underscores the need for stringent infection control measures [PMID:17803751].
Prognosis & Follow-up
Delays in diagnosing and treating burns impetigo led to worse outcomes, including prolonged symptoms and increased morbidity requiring multiple visits to the treatment center [PMID:24823337].
References
1 Aikins K, Prasad N, Menon S, Harvey JG, Holland AJ. Pediatric burn wound impetigo after grafting. Journal of burn care & research : official publication of the American Burn Association 2015. link 2 Xu Z, Shi L, Zhang C, Zhang L, Li X, Cao Y et al.. Nosocomial infection caused by class 1 integron-carrying Staphylococcus aureus in a hospital in South China. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2007. link
2 papers cited of 3 indexed.