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Cardiology58 papers

Eosinophilic gastroenteritis

Last edited: 4/15/2026

Overview

Eosinophilic gastroenteritis is a rare disorder characterized by infiltration of eosinophils into the gastrointestinal tract, leading to various gastrointestinal symptoms and complications 12.

Diagnosis

  • Presence of eosinophilic infiltration in gastrointestinal biopsies 12
  • Clinical symptoms may include abdominal pain, nausea, vomiting, and malabsorption 12
  • Elevated peripheral eosinophil count often observed 2
  • Imaging and endoscopic findings can support diagnosis but are non-specific 2
  • Management

  • First-line treatment typically involves corticosteroids (e.g., prednisone) to reduce eosinophilic infiltration 2
  • Adjunctive therapies may include dietary modifications, such as elemental diets, in refractory cases 2
  • Specific dosing details not provided in abstracts 2
  • Special Populations

  • Pediatrics: Case reports suggest eosinophilic gastroenteritis can occur in infants, potentially with extraintestinal manifestations like eosinophilic cystitis 1
  • Comorbidities: No specific management adjustments noted for comorbidities in the provided abstracts 2
  • Key Recommendations

  • Confirm diagnosis through gastrointestinal biopsy demonstrating eosinophilic infiltration (Evidence: Moderate) 2
  • Initiate corticosteroid therapy (e.g., prednisone) for symptomatic relief and reduction of eosinophilic infiltration (Evidence: Moderate) 2
  • Consider dietary interventions such as elemental diets for patients who do not respond to corticosteroids (Evidence: Weak) 2
  • References

    1 Peterson NE, Silverman A, Campbell JB. Eosinophilic cystitis and coexistent eosinophilic gastroenteritis in an infant. Pediatric radiology 1989. link 2 Owen-Smith MS. Eosinophilic gastroenteritis. The Australian and New Zealand journal of surgery 1975. link

    Original source

    1. [1]
      Eosinophilic cystitis and coexistent eosinophilic gastroenteritis in an infant.Peterson NE, Silverman A, Campbell JB Pediatric radiology (1989)
    2. [2]
      Eosinophilic gastroenteritis.Owen-Smith MS The Australian and New Zealand journal of surgery (1975)

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