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Psychiatry87 papers

Endocrine system complication of procedure

Last edited: 4/10/2026

Overview

Lithium therapy, commonly used for bipolar disorder, can trigger or worsen psoriasis 1. Psoriasis is also an independent risk factor for bipolar disorder 1.

Diagnosis

Management

  • Lithium therapy may trigger or worsen psoriasis 1.
  • Inositol supplementation may mitigate psoriasis in patients taking lithium 1.

    • Special Populations

    Key Recommendations

  • Lithium therapy may trigger or worsen psoriasis 1. (Evidence: Moderate)
  • Inositol supplementation may mitigate psoriasis in patients taking lithium 1. (Evidence: Moderate)

    • References

    1 Stamu-O'Brien C, Hoang M, Papoutsi I, Turk CB, Das A, Kroumpouzos G. Bipolar disorder in patients with psoriasis and the impact of lithium therapy on psoriasis. Clinics in dermatology 2025. link

    Original source

    1. [1]
      Bipolar disorder in patients with psoriasis and the impact of lithium therapy on psoriasis. — Stamu-O'Brien C, Hoang M, Papoutsi I, Turk CB, Das A, Kroumpouzos G Clinics in dermatology (2025)
    2. [2]
      Report of a patient with lithium-related alopecia and psoriasis. — Ghadirian AM, Lalinec-Michaud M The Journal of clinical psychiatry (1986)
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