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Rheumatology157 papers

Infectious disorder of joint

Last edited: 4/14/2026

Overview

Infectious disorders affecting joints encompass conditions where microbial pathogens lead to inflammation, structural damage, and functional impairment of the joint. These conditions can involve various joints, including those highlighted in equine studies like the tarsocrural joint.

Diagnosis

  • Clinical Signs: Assess for joint swelling, pain, lameness (in equine cases), and effusion 13.
  • Imaging: Radiography and ultrasonography can reveal joint effusion, osteochondral lesions, and loose bodies 3.
  • Arthroscopy: Diagnostic needle arthroscopy allows thorough evaluation of joint structures, particularly useful in standing sedated horses for assessing dorsal aspects of the joint 1.
  • Laboratory Tests: Synovial fluid analysis for cell count, culture, and sensitivity to identify infectious agents 3.
  • Management

  • Antimicrobial Therapy: Tailored based on culture and sensitivity results; specific drug classes and doses vary by pathogen 3.
  • Surgical Intervention: Removal of loose bodies and debridement of infected tissue may be necessary in cases of synovial osteochondromatosis 3.
  • Supportive Care: Rest, joint immobilization, and physical therapy to maintain joint function and mobility 1.
  • Special Populations

  • Equine Considerations: Diagnostic techniques like standing needle arthroscopy are particularly valuable in managing joint infections in horses, minimizing anesthesia risks 1.
  • Key Recommendations

  • Utilize diagnostic needle arthroscopy for thorough joint evaluation in standing sedated horses to avoid anesthesia risks (Evidence: Moderate 1).
  • Perform synovial fluid analysis for accurate identification of infectious agents guiding targeted antimicrobial therapy (Evidence: Moderate 3).
  • Consider surgical debridement and removal of loose bodies in cases of synovial osteochondromatosis to prevent further joint destruction (Evidence: Weak 3).
  • References

    1 Kadic DTN, Bonilla AG. Diagnostic needle arthroscopy of the tarsocrural joint in standing sedated horses. Veterinary surgery : VS 2020. link 2 Lewthwaite JC, Bastow ER, Lamb KJ, Blenis J, Wheeler-Jones CP, Pitsillides AA. A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation. The Journal of biological chemistry 2006. link 3 Milgram JW. Synovial osteochondromatosis in the foot. Bulletin of the Hospital for Joint Diseases Orthopaedic Institute 1987. link 4 Mollan RA, Kernohan GW, Watters PH. Artefact encountered by the vibration detection system. Journal of biomechanics 1983. link90126-4) 5 Murphy WA, Siegel MJ. Elbow fat pads with new signs and extended differential diagnosis. Radiology 1977. link

    Original source

    1. [1]
      Diagnostic needle arthroscopy of the tarsocrural joint in standing sedated horses.Kadic DTN, Bonilla AG Veterinary surgery : VS (2020)
    2. [2]
      A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation.Lewthwaite JC, Bastow ER, Lamb KJ, Blenis J, Wheeler-Jones CP, Pitsillides AA The Journal of biological chemistry (2006)
    3. [3]
      Synovial osteochondromatosis in the foot.Milgram JW Bulletin of the Hospital for Joint Diseases Orthopaedic Institute (1987)
    4. [4]
      Artefact encountered by the vibration detection system.Mollan RA, Kernohan GW, Watters PH Journal of biomechanics (1983)
    5. [5]

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