Overview
Pseudomonas species are Gram-negative bacilli that can cause urinary tract infections (UTIs), particularly in healthcare settings and in individuals with underlying urinary tract abnormalities or instrumentation 1. Pseudomonas aeruginosa is a common cause of complicated UTIs and is often associated with antibiotic resistance 1.Diagnosis
Diagnosis is typically made via urine culture, identifying Pseudomonas* species and determining antibiotic susceptibility 1. Complicated UTIs, often associated with Pseudomonas*, may require further investigation to identify underlying causes such as anatomical abnormalities or stones 1.Management
Treatment of Pseudomonas* UTIs generally requires antibiotics with appropriate activity against the specific isolate, often guided by susceptibility testing 1. Commonly used antibiotic classes for susceptible Pseudomonas* infections include fluoroquinolones, aminoglycosides, and extended-spectrum cephalosporins or carbapenems, depending on resistance patterns 1. Nonantibiotic interventions such as D-mannose, vaccines, probiotics, and cranberry products have shown efficacy in preventing recurrent UTIs, though their specific role in Pseudomonas* UTIs is not detailed 1.Special Populations
Key Recommendations
References
1 Han Z, Yi X, Li J, Liao D, Ai J. Nonantibiotic prophylaxis for urinary tract infections: a network meta-analysis of randomized controlled trials. Infection 2025. link