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Recurrent angina post rotational atherectomy

Last edited: 4/10/2026

Overview

Recurrent angina after rotational atherectomy (RA) for severely calcified coronary lesions may indicate incomplete revascularization or procedural complications. RA is a technique used during percutaneous coronary intervention (PCI) to debulk calcified plaque 13.

Diagnosis

Management

  • Rotational atherectomy followed by cutting balloon angioplasty before stenting demonstrated similar safety and efficacy regarding major adverse cardiovascular events (MACE) compared to RA with bare balloons 1.
  • Planned RA, compared to bailout RA, was associated with shorter procedural times, less contrast volume, fewer coronary dissections, and fewer stents used 3.
  • Fractional flow reserve (FFR)-guided revascularization was associated with lower rates of all-cause death, myocardial infarction, and MACE compared to angiography-guided revascularization in a meta-analysis of observational studies 2. However, when only randomized controlled trials (RCTs) were considered, no significant difference was observed for any endpoints 2.
  • Special Populations

    Key Recommendations

  • Rotational atherectomy followed by cutting balloon angioplasty before stenting is a viable strategy for severely calcified lesions, with outcomes similar to rotational atherectomy with bare balloons 1. (Evidence: Moderate)
  • Planned rotational atherectomy is associated with improved procedural efficiency and reduced complications compared to bailout rotational atherectomy 3. (Evidence: Moderate)
  • Fractional flow reserve-guided revascularization may reduce adverse cardiovascular outcomes compared to angiography-guided revascularization, particularly in settings with lower rates of revascularization and acute coronary syndromes 2. (Evidence: Moderate)
  • References

    1 Altobaishat O, Abouzid M, Tanashat M, Amin AM, Turkmani M, Abuelazm M. Rotational atherectomy with cutting balloon before stenting in severely calcified coronary lesions: a meta-analysis. Future cardiology 2024. link 2 Mangiacapra F, Paolucci L, Johnson NP, Viscusi MM, Ussia GP, Grigioni F et al.. Systematic review and meta-analysis of randomized and nonrandomized studies on fractional flow reserve-guided revascularization. Revista espanola de cardiologia (English ed.) 2024. link 3 Schwarz K, Lovatt S, Borovac JA, Parasuraman S, Kwok CS. Planned Versus Bailout Rotational Atherectomy: A Systematic Review and Meta-Analysis. Cardiovascular revascularization medicine : including molecular interventions 2022. link

    Original source

    1. [1]
      Rotational atherectomy with cutting balloon before stenting in severely calcified coronary lesions: a meta-analysis.Altobaishat O, Abouzid M, Tanashat M, Amin AM, Turkmani M, Abuelazm M Future cardiology (2024)
    2. [2]
      Systematic review and meta-analysis of randomized and nonrandomized studies on fractional flow reserve-guided revascularization.Mangiacapra F, Paolucci L, Johnson NP, Viscusi MM, Ussia GP, Grigioni F et al. Revista espanola de cardiologia (English ed.) (2024)
    3. [3]
      Planned Versus Bailout Rotational Atherectomy: A Systematic Review and Meta-Analysis.Schwarz K, Lovatt S, Borovac JA, Parasuraman S, Kwok CS Cardiovascular revascularization medicine : including molecular interventions (2022)

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