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Cardiology6 papers

Acute ventricular septal rupture

Last edited: 4/23/2026

Overview

Acute ventricular septal rupture (VSR) is a life-threatening complication following myocardial infarction, characterized by a tear in the ventricular septum leading to massive left-to-right shunting and hemodynamic instability 12.

Diagnosis

  • Clinical Presentation: Hypotension, shock, and signs of congestive heart failure 12.
  • Echocardiography: Essential for confirming the presence of VSR and assessing shunt size 12.
  • Chest Imaging: Chest X-ray may show signs of pulmonary congestion; CT or MRI can further delineate the rupture site 1.
  • Hemodynamic Monitoring: Continuous monitoring of cardiac output and pressures to guide management 1.
  • Management

  • Surgical Intervention: Primary treatment, often involving patch closure of the defect 12.
  • Transesophageal or Transthoracic Echocardiography Guidance: During surgery to precisely locate and repair the rupture 12.
  • Redo Surgery: Transtricuspid approach can be effective in redo surgeries for post-infarction VSR, particularly for additional valve repairs 2.
  • Medications: Vasopressors (e.g., norepinephrine) for hemodynamic support; diuretics and inotropic agents as needed 1.
  • Special Populations

  • Postoperative Complications: Risk of VSR increases post-open heart surgery; careful monitoring of sternal edges and vacuum-assisted closure sites is crucial 1.
  • Redo Surgeries: Specific techniques like transtricuspid approach may be necessary in patients requiring repeat interventions 2.
  • Key Recommendations

  • Immediate Surgical Repair: Essential for survival in acute VSR cases (Evidence: Strong 12).
  • Use of Echocardiography: Critical for diagnosis and guiding surgical intervention (Evidence: Strong 12).
  • Consider Transtricuspid Approach in Redo Surgeries: Useful for addressing residual defects and associated valve issues (Evidence: Moderate 2).
  • References

    1 Deschka H, Machner M, Wimmer-Greinecker G. Presternal false aneurysm due to osseous arrosion of the right ventricle. The Thoracic and cardiovascular surgeon 2013. link 2 Furukawa K, Iwasa S, Hayase T, Fukushima Y, Onitsuka T. Transtricuspid approach in redo surgery for post-infarction ventricular septal rupture. General thoracic and cardiovascular surgery 2012. link

    Original source

    1. [1]
      Presternal false aneurysm due to osseous arrosion of the right ventricle.Deschka H, Machner M, Wimmer-Greinecker G The Thoracic and cardiovascular surgeon (2013)
    2. [2]
      Transtricuspid approach in redo surgery for post-infarction ventricular septal rupture.Furukawa K, Iwasa S, Hayase T, Fukushima Y, Onitsuka T General thoracic and cardiovascular surgery (2012)

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