Diagnosis
Serial proximal 5 mm sections revealed consistent microscopic spread without discontinuous patterns, emphasizing the importance of thorough histological evaluation [PMID:10671885].
Management
A 10-mm clearance is adequate for grade 1 and 2 lesions, and 15 mm for grade 3 tumours, potentially allowing more patients to undergo partial penectomy instead of total penectomy [PMID:10671885].
Grade 3 tumours showed a maximum proximal histological extent of 10 mm, necessitating a 15 mm clearance to avoid recurrence [PMID:10671885].
Partial penectomy is effective in treating T1 and T2 penile carcinoma, yielding 80% five-year survival rates in the absence of inguinal metastases, with the residual stump maintaining functionality for urination and sexual activity [PMID:7498037].
Micrographic surgery, introduced by Mohs, achieves outcomes comparable to partial penectomy for small, distally located lesions up to 1 cm in diameter [PMID:7498037].
Radiotherapy is recommended for T1 and T2 primary penile carcinoma, with salvage partial penectomy addressing treatment failures [PMID:7498037].
References
1 Agrawal A, Pai D, Ananthakrishnan N, Smile SR, Ratnakar C. The histological extent of the local spread of carcinoma of the penis and its therapeutic implications. BJU international 2000. link 2 Magoha GA. Management of carcinoma of the penis: a review. East African medical journal 1995. link
2 papers cited of 3 indexed.