← Back to guidelines
Rheumatology5913 papers

Arthritis

Last edited: 4/23/2026

Overview

Arthritis encompasses a diverse group of conditions characterized by joint inflammation, pain, and functional impairment, including osteoarthritis, rheumatoid arthritis, gout, and crystal deposition diseases. Early diagnosis and tailored management are crucial for mitigating symptoms and preventing joint damage.

Diagnosis

  • Clinical Presentation: Assess joint pain, swelling, stiffness, and functional limitations. 1023
  • Laboratory Tests: Evaluate inflammatory markers (ESR, CRP), synovial fluid analysis for crystal identification, and specific biomarkers for different types of arthritis. 122223
  • Imaging: Utilize X-rays, MRI, and ultrasound for structural joint damage and to differentiate between inflammatory and non-inflammatory causes. 272130
  • Musculoskeletal Ultrasound: Valuable for differentiating gouty arthritis from rheumatoid arthritis and assessing crystal deposition. 27
  • Management

  • First-Line Treatments:
  • - Osteoarthritis: Analgesics (e.g., acetaminophen), NSAIDs, physical therapy. 3363 - Rheumatoid Arthritis: Disease-modifying antirheumatic drugs (DMARDs) like methotrexate, biologics (e.g., TNF inhibitors). 1562 - Gout: Nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, urate-lowering therapies (e.g., allopurinol). 124041
  • Adjunctive Treatments:
  • - Corticosteroids: Intra-articular injections for acute flares; systemic use in severe cases. 3362 - Occupational Therapy: Enhance functional capacity and self-management skills. 1622 - Lifestyle Modifications: Weight management, physical activity, and dietary adjustments (e.g., low purine diet for gout). 411

    Special Populations

  • Pregnancy: Use of DMARDs and NSAIDs requires careful consideration; alternatives like physical therapy and intra-articular corticosteroid injections may be preferred. 15
  • Pediatrics: Juvenile idiopathic arthritis management focuses on DMARDs and biologics tailored to pediatric safety profiles. 8
  • Elderly: Increased risk of comorbidities; individualized treatment plans considering polypharmacy and functional limitations. 1559
  • Comorbidities: Cardiovascular risk management is essential, especially in patients with rheumatoid arthritis (e.g., adherence to Life's Crucial 9 score). 418
  • Key Recommendations

  • Utilize musculoskeletal ultrasound for differentiating gouty arthritis from rheumatoid arthritis to enhance diagnostic accuracy. (Evidence: Moderate) 27
  • Implement synovial fluid analysis for definitive diagnosis of crystal-induced arthritis, improving clinical outcomes. (Evidence: Moderate) 2223
  • Tailor treatment plans for arthritis patients considering cardiovascular risk factors, emphasizing comprehensive lifestyle interventions. (Evidence: Moderate) 418
  • Optimize methotrexate dosing based on pharmacokinetic profiles to improve efficacy and minimize toxicity in rheumatoid arthritis patients. (Evidence: Moderate) 15
  • Incorporate patient-reported outcome measures in assessing health-related quality of life to guide individualized care plans. (Evidence: Moderate) 3333
  • References

    Showing 100 most recent of 626 indexed papers.

    1 Ma S, Tang L, Guo H, Niu J, Tang H. Differential expression of bone metabolism biomarkers in various types of arthritis and their diagnostic performance: a cross-sectional study. BMC musculoskeletal disorders 2026. link 2 Pan X, Cui G, Wang L, Xiao Y, Mei Y, Huang C. The role of musculoskeletal ultrasound in differentiating gouty arthritis from rheumatoid arthritis. Clinical rheumatology 2026. link 3 Wei X, Yuan J, Zhang Y, Wang Z, Hua J, He B et al.. Case Report of Gouty Arthritis Complicated by Septic Arthritis. Journal of visualized experiments : JoVE 2026. link 4 Huang XM, Zou YW, Lu J, Yang KM, Jia PW, Yang Y et al.. Association of Life's Crucial 9 score with mortality among adults with arthritis: A prospective cohort analysis. Public health 2026. link 5 Bouterse A, Pruneski JA, Liwag J, Stocker-Downing TH, Cage JM. Acute Paraspinal Compartment Syndrome Following Arthroscopic Management of Shoulder Arthritis: A Case Report. JBJS case connector 2026. link 6 Kong M, Walters H, Teh J. Updates in Deposition Arthritis Other Than Gout. Seminars in musculoskeletal radiology 2025. link 7 Sakellariou G, Adinolfi A, Madruga Dias J, Damiani A, Carrara G, Scirè CA et al.. Development of an algorithm for optimizing the implementation of ultrasound in the diagnostic workflow in clinical practice: preliminary phase of the RADIAL study, a project of the US Study Group of the Italian Society for Rheumatology. Reumatismo 2025. link 8 Germe Dağlioğlu ŞA, Balik Z, Özsoy Z, Dalkiliç YE, Batu ED, Başaran Ö et al.. Transformation of juvenile idiopathic arthritis in adult-oriented rheumatology care. Turkish journal of medical sciences 2025. link 9 Shan S, Oon S, Foote A. Outcomes of rheumatology referrals seen in a general medicine clinic. Internal medicine journal 2025. link 10 Swisher J, Sitton Z, Burbank K, Nelson C. Acute Monoarthritis: Diagnosis in Adults. American family physician 2025. link 11 Wang R, Ji C, Chen J, Zhang X, Hu Q, Liu C. Research advances in the treatment of arthritis from natural products (2014-present). Chinese journal of natural medicines 2025. link60862-4) 12 Zhang F, Gan Y, Xie W, Lu S, Zha Y, Liang Y et al.. A novel zinc ferrite nanoparticle protects against MSU-induced gout arthritis via Nrf2/NF-κB/NLRP3 pathway. Life sciences 2025. link 13 Balasubramaniam B, Jones AM. Observational suspected adverse drug reaction profiles of fluoro-pharmaceuticals and potential mimicry of per- and polyfluoroalkyl substances (PFAS) in the United Kingdom. PloS one 2025. link 14 Ciaffi J, Torrigiani G, Ruscitti P, Zambon A, Ursini F. No disproportionate reporting of inflammatory arthritis following COVID-19 vaccination: a pharmacovigilance study using VAERS data. Seminars in arthritis and rheumatism 2025. link 15 Yang Y, Liu Z, Chen J, Wang X, Jiao Z, Wang Z. Factors influencing methotrexate pharmacokinetics highlight the need for individualized dose adjustment: a systematic review. European journal of clinical pharmacology 2024. link 16 Sheerin M, O'Riordan C, Conneely M, Carey L, Ryan D, Galvin R et al.. Effectiveness of occupational therapy interventions on function and occupational performance among adults with conditions of the hand, wrist, and forearm: A systematic review and meta-analysis. Australian occupational therapy journal 2024. link 17 Caliogna L, Berni M, Torriani C, Mancuso ME, Di Minno MND, Brancato AM et al.. Pathogenesis of osteoarthritis, rheumatoid arthritis, and hemophilic arthropathy: The role of angiogenesis. Haemophilia : the official journal of the World Federation of Hemophilia 2024. link 18 Maduro AI, Saraiva AP, Mendes B, Carones A, Luís M, Santiago T et al.. 10-year experience of early arthritis clinic at a tertiary rheumatology center: achievements and challenges. ARP rheumatology 2024. link 19 Thiele RG. New Developments in Imaging in Crystalline Arthritis. Rheumatic diseases clinics of North America 2024. link 20 Matos IA, Dallazen JL, Reis LR, Souza LF, Bevevino RC, de Moura RD et al.. Targeting Myeloperoxidase Ameliorates Gouty Arthritis: A Virtual Screening Success Story. Journal of medicinal chemistry 2024. link 21 Sudoł-Szopińska I, Lanckoroński M, Teh J, Diekhoff T, Giraudo C, Chaudhary SR. Advanced Imaging of Gout and Other Inflammatory Diseases Around the Knee. Seminars in musculoskeletal radiology 2024. link 22 Mukerji S, Ryan P, Simmonds H, Buckley J, Birdling J. Concomitant septic and crystal arthropathy: a single-centre 10-year retrospective observational study in New Zealand. The New Zealand medical journal 2024. link 23 Nima C, Wanma L, Jing X, Duojie C, Gazang D, Ren Z. Elucidating the mechanism of the Tibetan medicine sanguotang in treating gouty arthritis through network pharmacology and in vivo experiments. The American journal of the medical sciences 2024. link 24 Liang Z, Wu D, Zhang H, Gu J. Association between asymptomatic hyperuricemia and risk of arthritis, findings from a US National Survey 2007-2018. BMJ open 2024. link 25 Turner SG, Robinson JRM, Pillemer KA, Reid MC. Prevalence Estimates of Arthritis and Activity-Limiting Pain Among Family Caregivers to Older Adults. The Gerontologist 2024. link 26 Kaur J, Ostrovskiy G, Hajicharalambous C. Iatrogenic Vertebral Artery Dissection with Posterior Fossa and Lateral Medullary Stroke After Uncomplicated Cervical Nerve Ablation. The Journal of emergency medicine 2024. link 27 Subhas N, Wu F, Fox MG, Nacey N, Aslam F, Blankenbaker DG et al.. ACR Appropriateness Criteria® Chronic Extremity Joint Pain-Suspected Inflammatory Arthritis, Crystalline Arthritis, or Erosive Osteoarthritis: 2022 Update. Journal of the American College of Radiology : JACR 2023. link 28 Tang CH. Research of Pathogenesis and Novel Therapeutics in Arthritis 3.0. International journal of molecular sciences 2023. link 29 Chan KK. A "Gold Standard" in the Management of Arthritis. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2023. link 30 Mayordomo L, Molina-Collada J, Uson J, García Vivar ML, Áñez Sturchio GA, Corrales A et al.. Ultrasonography in rheumatology: time to learn from patient views. Clinical rheumatology 2023. link 31 Woodbury MJ, Smith JS, Merola JF. Dupilumab-Associated Arthritis: A Dermatology-Rheumatology Perspective. American journal of clinical dermatology 2023. link 32 Maugars Y, Bard H, Latourte A, Senbel É, Flipo RM, Eymard F. Musculoskeletal corticosteroid injections: Recommendations of the French Society for Rheumatology (SFR). Joint bone spine 2023. link 33 Knight E, Schifferdecker KE, Eakin GS, Reeve BB. Selecting patient-reported outcome measures of health-related quality of life in adult rheumatology: quality and breadth of coverage. Rheumatology international 2023. link 34 Chua CG, Thong BY. Inflammatory Arthritis Among Military Servicemen From a Rheumatology Center in Singapore. Military medicine 2023. link 35 Oliviero F, Mandell BF. Synovial fluid analysis: Relevance for daily clinical practice. Best practice & research. Clinical rheumatology 2023. link 36 Xiao Y, Zhang L. Mechanistic and therapeutic insights into the function of NLRP3 inflammasome in sterile arthritis. Frontiers in immunology 2023. link 37 Ghaddaf AA, Alomari MS, AlHarbi FA, Alquhaibi MS, Alsharef JF, Alsharef NK et al.. Public awareness about arthritic diseases in Saudi Arabia: a systematic review and meta-analysis. International orthopaedics 2023. link 38 Zaninelli TH, Martelossi-Cebinelli G, Saraiva-Santos T, Borghi SM, Fattori V, Casagrande R et al.. New drug targets for the treatment of gout arthritis: what's new?. Expert opinion on therapeutic targets 2023. link 39 Wei Q, Zhu X, Wang L, Zhang W, Yang X, Wei W. Extracellular matrix in synovium development, homeostasis and arthritis disease. International immunopharmacology 2023. link 40 Laosuksri P, Phrintrakul N, Gumtorntip W, Na-Nan K, Wongthanee A, Kasitanon N et al.. Non-loading versus loading low-dose colchicine in acute crystal-associated arthritis: A double-blinded randomized controlled study. International journal of rheumatic diseases 2023. link 41 Lafforgue A, Lambert C, Dubost JJ, Tournadre A, Soubrier M, Couderc M. Performance of a diagnostic score for gouty arthritis: results from a cohort of acute arthritis suspected of being septic. Rheumatology international 2023. link 42 Sudah SY, Moverman MA, Masood R, Mojica ES, Pagani NR, Puzzitiello RN et al.. The Majority of Sports Medicine and Arthroscopy-Related Randomized Controlled Trials Reporting Nonsignificant Results Are Statistically Fragile. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2023. link 43 Hinz M, Lutter C, Mueller-Rath R, Niemeyer P, Miltner O, Tischer T. The German Arthroscopy Registry DART: what has happened after 5 years?. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 2023. link 44 Roulet S, Nguyen MV, Cohen G, Sos C, Servasier L, Laulan J et al.. Total arthrodesis for non-rheumatoid wrists: Outcomes at 5 and 20years of follow-up. Orthopaedics & traumatology, surgery & research : OTSR 2023. link 45 Upfill-Brown A, Paisner N, Sassoon A. Racial disparities in post-operative complications and discharge destination following total joints arthroplasty: a national database study. Archives of orthopaedic and trauma surgery 2023. link 46 Ghosh N, Couette N, van Binsbergen WH, Weinmann SC, Jivanelli B, Shea B et al.. Identification of outcome domains in immune checkpoint inhibitor-induced inflammatory arthritis and polymyalgia rheumatica: A scoping review by the OMERACT irAE working group. Seminars in arthritis and rheumatism 2023. link 47 Dubin JA, Bains SS, Chen Z, Salib CG, Nace J, Mont MA et al.. Race Associated With Increased Complication Rates After Total Knee Arthroplasty. The Journal of arthroplasty 2023. link 48 Fratini S, Meena A, Alesi D, Cammisa E, Zaffagnini S, Marcheggiani Muccioli GM. Does Implant Design Influence Failure Rate of Lateral Unicompartmental Knee Arthroplasty? A Meta-Analysis. The Journal of arthroplasty 2022. link 49 Zeng L, Yang T, Yang K, Yu G, Li J, Xiang W et al.. Efficacy and Safety of Curcumin and . Frontiers in immunology 2022. link 50 Dunham K, Tesoriero P, Wollstein R. The Use of Ultrasound to Differentiate Between Gout and Infection in the Wrist. Current rheumatology reviews 2022. link 51 Lubowitz JH, Brand JC, Rossi MJ. Medical Journal Websites Include Online-Only Content Plus Intriguing and Unique Features. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2022. link 52 Brownlee J, Sheridan E, Synnott A, McCormack A, Bell M, Fitzgerald O. A Lifestyle Management for Arthritis Group education intervention for people with inflammatory and degenerative arthritis: An observational study. Musculoskeletal care 2022. link 53 Ho JSY, Zhou AK, Tran C, Jou E, Girish M, Thahir A et al.. Management of a Hot Swollen Joint in the Acute Setting. Current rheumatology reviews 2022. link 54 Reed M, Le Souëf T, Rampono E. Pilot study of a machine-learning tool to assist in the diagnosis of hand arthritis. Internal medicine journal 2022. link 55 Reed M, Rampono B, Turner W, Harsanyi A, Lim A, Paramalingam S et al.. A multicentre validation study of a smartphone application to screen hand arthritis. BMC musculoskeletal disorders 2022. link 56 Houck EL, Petritz OA, Chen LR, Fletcher OJ, Thomson AE, Flammer K. Clinicopathologic, Gross Necropsy, and Histopathologic Effects of High-Dose, Repeated Meloxicam Administration in Rhode Island Red Chickens (. Journal of avian medicine and surgery 2022. link 57 Rasheed Kayani R, Shamim R, Sultana Munir S, Sultana M, Nazir SUR, Riaz H et al.. Medicinal Plants and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) in Treatment of Arthritis: A Literature Review. Alternative therapies in health and medicine 2022. link 58 Scanu A, Lorenzin M, Luisetto R, Galozzi P, Ortolan A, Oliviero F et al.. Identification in synovial fluid of a new potential pathogenic player in arthropathies. Experimental biology and medicine (Maywood, N.J.) 2022. link 59 Alvandi B, Hartwell M, Butler B, Johnson D, Christian RA, Castle J et al.. Arthroscopic Case Volumes Among Orthopaedic Surgery Residents and Orthopaedic Sports Medicine Fellows: An Analysis of ACGME Case Log Data. Journal of surgical orthopaedic advances 2022. link 60 Calmes SH. Women of the First Anesthesia Journal. Anesthesia and analgesia 2022. link 61 Sapkota B, Shrestha R, Giri S. Community pharmacy-based SOAP notes documentation. Medicine 2022. link 62 Uson J, Rodriguez-García SC, Castellanos-Moreira R, O'Neill TW, Doherty M, Boesen M et al.. EULAR recommendations for intra-articular therapies. Annals of the rheumatic diseases 2021. link 63 Stone S, Malanga GA, Capella T. Corticosteroids: Review of the History, the Effectiveness, and Adverse Effects in the Treatment of Joint Pain. Pain physician 2021. link 64 Luzzi A, Hellwinkel J, O'Connor M, Crutchfield C, Lynch TS. The Efficacy of Arthroscopic Simulation Training on Clinical Ability: A Systematic Review. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2021. link 65 Baron JE, Parker EA, Wolf BR, Duchman KR, Westermann RW. PROMIS Versus Legacy Patient-Reported Outcome Measures for Sports Medicine Patients Undergoing Arthroscopic Knee, Shoulder, and Hip Interventions: A Systematic Review. The Iowa orthopaedic journal 2021. link 66 Rustad AM, Nolan BE, Ollech A, Boctor MJ, Paller AS. Incorporating joint pain screening into the pediatric dermatologic examination. Pediatric dermatology 2021. link 67 Dey M, Zhao SS. Google search data as a novel adjunct to patient and public involvement in rheumatology research. Rheumatology international 2021. link 68 Cordeiro JV, Lopes CA, Faria PL, Aguiar P, Cercas MJ, Victorino G et al.. Biobanks for aging research - perceptions and choices among rheumatology outpatients. Acta reumatologica portuguesa 2021. link 69 Baggio C, Sfriso P, Cignarella A, Galozzi P, Scanu A, Mastrotto F et al.. Phagocytosis and inflammation in crystal-induced arthritis: a synovial fluid and in vitro study. Clinical and experimental rheumatology 2021. link 70 Li WH, Han JR, Ren PP, Xie Y, Jiang DY. Exploration of the mechanism of Zisheng Shenqi decoction against gout arthritis using network pharmacology. Computational biology and chemistry 2021. link 71 Xue Y, Li R, Fang P, Ye ZQ, Zhao Y, Zhou Y et al.. NLRP3 inflammasome inhibitor cucurbitacin B suppresses gout arthritis in mice. Journal of molecular endocrinology 2021. link 72 Zamudio-Cuevas Y, Martínez-Nava GA, Martínez-Flores K, Ventura-Ríos L, Vazquez-Mellado J, Rodríguez-Henríquez P et al.. Synovial fluid analysis for the enhanced clinical diagnosis of crystal arthropathies in a tertiary care institution. Clinical rheumatology 2021. link 73 O'Brien P, Conley B, Bunzli S, Bullen J, Coffin J, Persaud J et al.. Staying moving, staying strong: Protocol for developing culturally appropriate information for Aboriginal people with osteoarthritis, rheumatoid arthritis, lupus and gout. PloS one 2021. link 74 Liu W, Ma W, Liu H, Li C, Zhang Y, Liu J et al.. Stroke risk in arthritis: A systematic review and meta-analysis of cohort studies. PloS one 2021. link 75 Grobelski J, Recker F, Wilsmann-Theis D, Hartung W, Karakostas P, Brossart P et al.. Establishment and validation of a didactic musculoskeletal ultrasound course for dermatologists using an innovative handheld ultrasound system - the MUDE study (Musculoskeletal Ultrasound in Dermatology). Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2021. link 76 Ge R, Zhang J, Yang Z. Evaluation of Minimally Invasive Arthroscopy Technology in Sports Medicine-An Evaluation of Nano Silver Disinfectants. Journal of nanoscience and nanotechnology 2021. link 77 Chellamuthu G, Muthu S, Damodaran UK, Rangabashyam R. "Only 50% of randomized trials have high level of confidence in arthroscopy and sports medicine"-a spin-based assessment. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 2021. link 78 Cushman DM, Teramoto M, Asay A, Clements ND, McCormick ZL. Corticosteroid and Local Anesthetic Use Trends for Large Joint and Bursa Injections: Results of a Survey of Sports Medicine Physicians. PM & R : the journal of injury, function, and rehabilitation 2021. link 79 Evans CH, Ghivizzani SC, Robbins PD. Orthopaedic Gene Therapy: Twenty-Five Years On. JBJS reviews 2021. link 80 Yang KH, Kaufmann CN, Nafsu R, Lifset ET, Nguyen K, Sexton M et al.. Cannabis: An Emerging Treatment for Common Symptoms in Older Adults. Journal of the American Geriatrics Society 2021. link 81 Robertson DS. A hypothesis of bone joint defects. Medical hypotheses 2020. link 82 Lubowitz JH, Brand JC, Rossi MJ. AANA20: The 2020 Annual Meeting of the Arthroscopy Association of North America. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2020. link 83 Loyola-Sanchez A, Pelaez-Ballestas I, Crowshoe L, Lacaille D, Henderson R, Rame A et al.. "There are still a lot of things that I need": a qualitative study exploring opportunities to improve the health services of First Nations People with arthritis seen at an on-reserve outreach rheumatology clinic. BMC health services research 2020. link 84 Chisari E, Yaghmour KM, Peat F, Khan W. Patients Presenting with a Hot, Swollen Joint: A Single-Centre Retrospective Analysis. Current rheumatology reviews 2020. link 85 Bai B, Wang H, Liu T, Rivenson Y, FitzGerald J, Ozcan A. Pathological crystal imaging with single-shot computational polarized light microscopy. Journal of biophotonics 2020. link 86 Zhang J, Jiang J, Bao G, Xu G, Wang L, Chen J et al.. Interaction between C/EBPβ and RUNX2 promotes apoptosis of chondrocytes during human lumbar facet joint degeneration. Journal of molecular histology 2020. link 87 Heyer JH, Perim DA, Amdur RL, Pandarinath R. Impact of smoking on outcomes following knee and shoulder arthroscopy. European journal of orthopaedic surgery & traumatology : orthopedie traumatologie 2020. link 88 Atkinson TJ, Fudin J. Nonsteroidal Antiinflammatory Drugs for Acute and Chronic Pain. Physical medicine and rehabilitation clinics of North America 2020. link 89 Suissa M, LeLorier J. Pharmacologically pertinent period of effect (PPPE). Pharmacoepidemiology and drug safety 2020. link 90 Butenas ALE, Rollins KS, Matney JE, Williams AC, Kleweno TE, Parr SK et al.. No effect of endoperoxide 4 or thromboxane A. Experimental physiology 2020. link 91 Venuturupalli RS, Sufka P, Bhana S. Digital Medicine in Rheumatology: Challenges and Opportunities. Rheumatic diseases clinics of North America 2019. link 92 Nelson R. Stem Cell Joint Therapy: Promising, but Not Ready for Prime Time. The American journal of nursing 2019. link 93 Lubowitz JH, Brand JC, Rossi MJ. Arthroscopy, Sports Medicine, and Rehabilitation (ASMAR): A New, Open Access, Electronic Journal. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2019. link 94 Bhushan D, Agarwal M. Guaiacum Toxicity: An Unusal Poisoning. The Journal of the Association of Physicians of India 2019. link 95 Martinez-Arroyo G, Ramos-Gomez S, Rojero-Gil EK, Rojas-Gongora JA, Barajas-Ochoa A, Bustamante-Montes LP et al.. Potential uses of an infodemiology approach for health-care services for rheumatology. Clinical rheumatology 2019. link 96 Desmarais J, Chu CQ. Utility of Anakinra in Acute Crystalline Diseases: A Retrospective Study Comparing a University Hospital with a Veterans Affairs Medical Center. The Journal of rheumatology 2019. link 97 Chen XM, Zhao Y, Wu XD, Wang MJ, Yu H, Lu JJ et al.. Novel findings from determination of common expressed plasma exosomal microRNAs in patients with psoriatic arthritis, psoriasis vulgaris, rheumatoid arthritis, and gouty arthritis. Discovery medicine 2019. link 98 Ellis JM. Acute monoarthritis. JAAPA : official journal of the American Academy of Physician Assistants 2019. link 99 Stamp LK, Anderson NG, Becce F, Rajeswari M, Polson M, Guyen O et al.. Clinical Utility of Multi-Energy Spectral Photon-Counting Computed Tomography in Crystal Arthritis. Arthritis & rheumatology (Hoboken, N.J.) 2019. link 100 Lu CH, Hsiao YF, Hsu HC, Ko YL, Lin TS, Chen LF et al.. Can ultrasound differentiate acute erosive arthritis associated with osteomyelitis, rheumatoid arthritis, or gouty arthritis?. International journal of rheumatic diseases 2019. link

    Original source

    1. [1]
    2. [2]
      The role of musculoskeletal ultrasound in differentiating gouty arthritis from rheumatoid arthritis.Pan X, Cui G, Wang L, Xiao Y, Mei Y, Huang C Clinical rheumatology (2026)
    3. [3]
      Case Report of Gouty Arthritis Complicated by Septic Arthritis.Wei X, Yuan J, Zhang Y, Wang Z, Hua J, He B et al. Journal of visualized experiments : JoVE (2026)
    4. [4]
      Association of Life's Crucial 9 score with mortality among adults with arthritis: A prospective cohort analysis.Huang XM, Zou YW, Lu J, Yang KM, Jia PW, Yang Y et al. Public health (2026)
    5. [5]
      Acute Paraspinal Compartment Syndrome Following Arthroscopic Management of Shoulder Arthritis: A Case Report.Bouterse A, Pruneski JA, Liwag J, Stocker-Downing TH, Cage JM JBJS case connector (2026)
    6. [6]
      Updates in Deposition Arthritis Other Than Gout.Kong M, Walters H, Teh J Seminars in musculoskeletal radiology (2025)
    7. [7]
    8. [8]
      Transformation of juvenile idiopathic arthritis in adult-oriented rheumatology care.Germe Dağlioğlu ŞA, Balik Z, Özsoy Z, Dalkiliç YE, Batu ED, Başaran Ö et al. Turkish journal of medical sciences (2025)
    9. [9]
      Outcomes of rheumatology referrals seen in a general medicine clinic.Shan S, Oon S, Foote A Internal medicine journal (2025)
    10. [10]
      Acute Monoarthritis: Diagnosis in Adults.Swisher J, Sitton Z, Burbank K, Nelson C American family physician (2025)
    11. [11]
      Research advances in the treatment of arthritis from natural products (2014-present).Wang R, Ji C, Chen J, Zhang X, Hu Q, Liu C Chinese journal of natural medicines (2025)
    12. [12]
      A novel zinc ferrite nanoparticle protects against MSU-induced gout arthritis via Nrf2/NF-κB/NLRP3 pathway.Zhang F, Gan Y, Xie W, Lu S, Zha Y, Liang Y et al. Life sciences (2025)
    13. [13]
    14. [14]
      No disproportionate reporting of inflammatory arthritis following COVID-19 vaccination: a pharmacovigilance study using VAERS data.Ciaffi J, Torrigiani G, Ruscitti P, Zambon A, Ursini F Seminars in arthritis and rheumatism (2025)
    15. [15]
      Factors influencing methotrexate pharmacokinetics highlight the need for individualized dose adjustment: a systematic review.Yang Y, Liu Z, Chen J, Wang X, Jiao Z, Wang Z European journal of clinical pharmacology (2024)
    16. [16]
    17. [17]
      Pathogenesis of osteoarthritis, rheumatoid arthritis, and hemophilic arthropathy: The role of angiogenesis.Caliogna L, Berni M, Torriani C, Mancuso ME, Di Minno MND, Brancato AM et al. Haemophilia : the official journal of the World Federation of Hemophilia (2024)
    18. [18]
      10-year experience of early arthritis clinic at a tertiary rheumatology center: achievements and challenges.Maduro AI, Saraiva AP, Mendes B, Carones A, Luís M, Santiago T et al. ARP rheumatology (2024)
    19. [19]
      New Developments in Imaging in Crystalline Arthritis.Thiele RG Rheumatic diseases clinics of North America (2024)
    20. [20]
      Targeting Myeloperoxidase Ameliorates Gouty Arthritis: A Virtual Screening Success Story.Matos IA, Dallazen JL, Reis LR, Souza LF, Bevevino RC, de Moura RD et al. Journal of medicinal chemistry (2024)
    21. [21]
      Advanced Imaging of Gout and Other Inflammatory Diseases Around the Knee.Sudoł-Szopińska I, Lanckoroński M, Teh J, Diekhoff T, Giraudo C, Chaudhary SR Seminars in musculoskeletal radiology (2024)
    22. [22]
      Concomitant septic and crystal arthropathy: a single-centre 10-year retrospective observational study in New Zealand.Mukerji S, Ryan P, Simmonds H, Buckley J, Birdling J The New Zealand medical journal (2024)
    23. [23]
      Elucidating the mechanism of the Tibetan medicine sanguotang in treating gouty arthritis through network pharmacology and in vivo experiments.Nima C, Wanma L, Jing X, Duojie C, Gazang D, Ren Z The American journal of the medical sciences (2024)
    24. [24]
    25. [25]
      Prevalence Estimates of Arthritis and Activity-Limiting Pain Among Family Caregivers to Older Adults.Turner SG, Robinson JRM, Pillemer KA, Reid MC The Gerontologist (2024)
    26. [26]
    27. [27]
      ACR Appropriateness Criteria® Chronic Extremity Joint Pain-Suspected Inflammatory Arthritis, Crystalline Arthritis, or Erosive Osteoarthritis: 2022 Update.Subhas N, Wu F, Fox MG, Nacey N, Aslam F, Blankenbaker DG et al. Journal of the American College of Radiology : JACR (2023)
    28. [28]
      Research of Pathogenesis and Novel Therapeutics in Arthritis 3.0.Tang CH International journal of molecular sciences (2023)
    29. [29]
      A "Gold Standard" in the Management of Arthritis.Chan KK Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases (2023)
    30. [30]
      Ultrasonography in rheumatology: time to learn from patient views.Mayordomo L, Molina-Collada J, Uson J, García Vivar ML, Áñez Sturchio GA, Corrales A et al. Clinical rheumatology (2023)
    31. [31]
      Dupilumab-Associated Arthritis: A Dermatology-Rheumatology Perspective.Woodbury MJ, Smith JS, Merola JF American journal of clinical dermatology (2023)
    32. [32]
      Musculoskeletal corticosteroid injections: Recommendations of the French Society for Rheumatology (SFR).Maugars Y, Bard H, Latourte A, Senbel É, Flipo RM, Eymard F Joint bone spine (2023)
    33. [33]
    34. [34]
    35. [35]
      Synovial fluid analysis: Relevance for daily clinical practice.Oliviero F, Mandell BF Best practice & research. Clinical rheumatology (2023)
    36. [36]
    37. [37]
      Public awareness about arthritic diseases in Saudi Arabia: a systematic review and meta-analysis.Ghaddaf AA, Alomari MS, AlHarbi FA, Alquhaibi MS, Alsharef JF, Alsharef NK et al. International orthopaedics (2023)
    38. [38]
      New drug targets for the treatment of gout arthritis: what's new?Zaninelli TH, Martelossi-Cebinelli G, Saraiva-Santos T, Borghi SM, Fattori V, Casagrande R et al. Expert opinion on therapeutic targets (2023)
    39. [39]
      Extracellular matrix in synovium development, homeostasis and arthritis disease.Wei Q, Zhu X, Wang L, Zhang W, Yang X, Wei W International immunopharmacology (2023)
    40. [40]
      Non-loading versus loading low-dose colchicine in acute crystal-associated arthritis: A double-blinded randomized controlled study.Laosuksri P, Phrintrakul N, Gumtorntip W, Na-Nan K, Wongthanee A, Kasitanon N et al. International journal of rheumatic diseases (2023)
    41. [41]
      Performance of a diagnostic score for gouty arthritis: results from a cohort of acute arthritis suspected of being septic.Lafforgue A, Lambert C, Dubost JJ, Tournadre A, Soubrier M, Couderc M Rheumatology international (2023)
    42. [42]
      The Majority of Sports Medicine and Arthroscopy-Related Randomized Controlled Trials Reporting Nonsignificant Results Are Statistically Fragile.Sudah SY, Moverman MA, Masood R, Mojica ES, Pagani NR, Puzzitiello RN et al. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association (2023)
    43. [43]
      The German Arthroscopy Registry DART: what has happened after 5 years?Hinz M, Lutter C, Mueller-Rath R, Niemeyer P, Miltner O, Tischer T Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA (2023)
    44. [44]
      Total arthrodesis for non-rheumatoid wrists: Outcomes at 5 and 20years of follow-up.Roulet S, Nguyen MV, Cohen G, Sos C, Servasier L, Laulan J et al. Orthopaedics & traumatology, surgery & research : OTSR (2023)
    45. [45]
    46. [46]
      Identification of outcome domains in immune checkpoint inhibitor-induced inflammatory arthritis and polymyalgia rheumatica: A scoping review by the OMERACT irAE working group.Ghosh N, Couette N, van Binsbergen WH, Weinmann SC, Jivanelli B, Shea B et al. Seminars in arthritis and rheumatism (2023)
    47. [47]
      Race Associated With Increased Complication Rates After Total Knee Arthroplasty.Dubin JA, Bains SS, Chen Z, Salib CG, Nace J, Mont MA et al. The Journal of arthroplasty (2023)
    48. [48]
      Does Implant Design Influence Failure Rate of Lateral Unicompartmental Knee Arthroplasty? A Meta-Analysis.Fratini S, Meena A, Alesi D, Cammisa E, Zaffagnini S, Marcheggiani Muccioli GM The Journal of arthroplasty (2022)
    49. [49]
      Efficacy and Safety of Curcumin and Zeng L, Yang T, Yang K, Yu G, Li J, Xiang W et al. Frontiers in immunology (2022)
    50. [50]
      The Use of Ultrasound to Differentiate Between Gout and Infection in the Wrist.Dunham K, Tesoriero P, Wollstein R Current rheumatology reviews (2022)
    51. [51]
      Medical Journal Websites Include Online-Only Content Plus Intriguing and Unique Features.Lubowitz JH, Brand JC, Rossi MJ Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association (2022)
    52. [52]
      A Lifestyle Management for Arthritis Group education intervention for people with inflammatory and degenerative arthritis: An observational study.Brownlee J, Sheridan E, Synnott A, McCormack A, Bell M, Fitzgerald O Musculoskeletal care (2022)
    53. [53]
      Management of a Hot Swollen Joint in the Acute Setting.Ho JSY, Zhou AK, Tran C, Jou E, Girish M, Thahir A et al. Current rheumatology reviews (2022)
    54. [54]
      Pilot study of a machine-learning tool to assist in the diagnosis of hand arthritis.Reed M, Le Souëf T, Rampono E Internal medicine journal (2022)
    55. [55]
      A multicentre validation study of a smartphone application to screen hand arthritis.Reed M, Rampono B, Turner W, Harsanyi A, Lim A, Paramalingam S et al. BMC musculoskeletal disorders (2022)
    56. [56]
      Clinicopathologic, Gross Necropsy, and Histopathologic Effects of High-Dose, Repeated Meloxicam Administration in Rhode Island Red Chickens (Houck EL, Petritz OA, Chen LR, Fletcher OJ, Thomson AE, Flammer K Journal of avian medicine and surgery (2022)
    57. [57]
      Medicinal Plants and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) in Treatment of Arthritis: A Literature Review.Rasheed Kayani R, Shamim R, Sultana Munir S, Sultana M, Nazir SUR, Riaz H et al. Alternative therapies in health and medicine (2022)
    58. [58]
      Identification in synovial fluid of a new potential pathogenic player in arthropathies.Scanu A, Lorenzin M, Luisetto R, Galozzi P, Ortolan A, Oliviero F et al. Experimental biology and medicine (Maywood, N.J.) (2022)
    59. [59]
      Arthroscopic Case Volumes Among Orthopaedic Surgery Residents and Orthopaedic Sports Medicine Fellows: An Analysis of ACGME Case Log Data.Alvandi B, Hartwell M, Butler B, Johnson D, Christian RA, Castle J et al. Journal of surgical orthopaedic advances (2022)
    60. [60]
      Women of the First Anesthesia Journal.Calmes SH Anesthesia and analgesia (2022)
    61. [61]
      Community pharmacy-based SOAP notes documentation.Sapkota B, Shrestha R, Giri S Medicine (2022)
    62. [62]
      EULAR recommendations for intra-articular therapies.Uson J, Rodriguez-García SC, Castellanos-Moreira R, O'Neill TW, Doherty M, Boesen M et al. Annals of the rheumatic diseases (2021)
    63. [63]
    64. [64]
      The Efficacy of Arthroscopic Simulation Training on Clinical Ability: A Systematic Review.Luzzi A, Hellwinkel J, O'Connor M, Crutchfield C, Lynch TS Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association (2021)
    65. [65]
    66. [66]
      Incorporating joint pain screening into the pediatric dermatologic examination.Rustad AM, Nolan BE, Ollech A, Boctor MJ, Paller AS Pediatric dermatology (2021)
    67. [67]
    68. [68]
      Biobanks for aging research - perceptions and choices among rheumatology outpatients.Cordeiro JV, Lopes CA, Faria PL, Aguiar P, Cercas MJ, Victorino G et al. Acta reumatologica portuguesa (2021)
    69. [69]
      Phagocytosis and inflammation in crystal-induced arthritis: a synovial fluid and in vitro study.Baggio C, Sfriso P, Cignarella A, Galozzi P, Scanu A, Mastrotto F et al. Clinical and experimental rheumatology (2021)
    70. [70]
      Exploration of the mechanism of Zisheng Shenqi decoction against gout arthritis using network pharmacology.Li WH, Han JR, Ren PP, Xie Y, Jiang DY Computational biology and chemistry (2021)
    71. [71]
      NLRP3 inflammasome inhibitor cucurbitacin B suppresses gout arthritis in mice.Xue Y, Li R, Fang P, Ye ZQ, Zhao Y, Zhou Y et al. Journal of molecular endocrinology (2021)
    72. [72]
      Synovial fluid analysis for the enhanced clinical diagnosis of crystal arthropathies in a tertiary care institution.Zamudio-Cuevas Y, Martínez-Nava GA, Martínez-Flores K, Ventura-Ríos L, Vazquez-Mellado J, Rodríguez-Henríquez P et al. Clinical rheumatology (2021)
    73. [73]
    74. [74]
      Stroke risk in arthritis: A systematic review and meta-analysis of cohort studies.Liu W, Ma W, Liu H, Li C, Zhang Y, Liu J et al. PloS one (2021)
    75. [75]
      Establishment and validation of a didactic musculoskeletal ultrasound course for dermatologists using an innovative handheld ultrasound system - the MUDE study (Musculoskeletal Ultrasound in Dermatology).Grobelski J, Recker F, Wilsmann-Theis D, Hartung W, Karakostas P, Brossart P et al. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG (2021)
    76. [76]
    77. [77]
      "Only 50% of randomized trials have high level of confidence in arthroscopy and sports medicine"-a spin-based assessment.Chellamuthu G, Muthu S, Damodaran UK, Rangabashyam R Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA (2021)
    78. [78]
      Corticosteroid and Local Anesthetic Use Trends for Large Joint and Bursa Injections: Results of a Survey of Sports Medicine Physicians.Cushman DM, Teramoto M, Asay A, Clements ND, McCormick ZL PM & R : the journal of injury, function, and rehabilitation (2021)
    79. [79]
      Orthopaedic Gene Therapy: Twenty-Five Years On.Evans CH, Ghivizzani SC, Robbins PD JBJS reviews (2021)
    80. [80]
      Cannabis: An Emerging Treatment for Common Symptoms in Older Adults.Yang KH, Kaufmann CN, Nafsu R, Lifset ET, Nguyen K, Sexton M et al. Journal of the American Geriatrics Society (2021)
    81. [81]
      A hypothesis of bone joint defects.Robertson DS Medical hypotheses (2020)
    82. [82]
      AANA20: The 2020 Annual Meeting of the Arthroscopy Association of North America.Lubowitz JH, Brand JC, Rossi MJ Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association (2020)
    83. [83]
    84. [84]
      Patients Presenting with a Hot, Swollen Joint: A Single-Centre Retrospective Analysis.Chisari E, Yaghmour KM, Peat F, Khan W Current rheumatology reviews (2020)
    85. [85]
      Pathological crystal imaging with single-shot computational polarized light microscopy.Bai B, Wang H, Liu T, Rivenson Y, FitzGerald J, Ozcan A Journal of biophotonics (2020)
    86. [86]
      Interaction between C/EBPβ and RUNX2 promotes apoptosis of chondrocytes during human lumbar facet joint degeneration.Zhang J, Jiang J, Bao G, Xu G, Wang L, Chen J et al. Journal of molecular histology (2020)
    87. [87]
      Impact of smoking on outcomes following knee and shoulder arthroscopy.Heyer JH, Perim DA, Amdur RL, Pandarinath R European journal of orthopaedic surgery & traumatology : orthopedie traumatologie (2020)
    88. [88]
      Nonsteroidal Antiinflammatory Drugs for Acute and Chronic Pain.Atkinson TJ, Fudin J Physical medicine and rehabilitation clinics of North America (2020)
    89. [89]
      Pharmacologically pertinent period of effect (PPPE).Suissa M, LeLorier J Pharmacoepidemiology and drug safety (2020)
    90. [90]
      No effect of endoperoxide 4 or thromboxane AButenas ALE, Rollins KS, Matney JE, Williams AC, Kleweno TE, Parr SK et al. Experimental physiology (2020)
    91. [91]
      Digital Medicine in Rheumatology: Challenges and Opportunities.Venuturupalli RS, Sufka P, Bhana S Rheumatic diseases clinics of North America (2019)
    92. [92]
      Stem Cell Joint Therapy: Promising, but Not Ready for Prime Time.Nelson R The American journal of nursing (2019)
    93. [93]
      Arthroscopy, Sports Medicine, and Rehabilitation (ASMAR): A New, Open Access, Electronic Journal.Lubowitz JH, Brand JC, Rossi MJ Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association (2019)
    94. [94]
      Guaiacum Toxicity: An Unusal Poisoning.Bhushan D, Agarwal M The Journal of the Association of Physicians of India (2019)
    95. [95]
      Potential uses of an infodemiology approach for health-care services for rheumatology.Martinez-Arroyo G, Ramos-Gomez S, Rojero-Gil EK, Rojas-Gongora JA, Barajas-Ochoa A, Bustamante-Montes LP et al. Clinical rheumatology (2019)
    96. [96]
    97. [97]
    98. [98]
      Acute monoarthritis.Ellis JM JAAPA : official journal of the American Academy of Physician Assistants (2019)
    99. [99]
      Clinical Utility of Multi-Energy Spectral Photon-Counting Computed Tomography in Crystal Arthritis.Stamp LK, Anderson NG, Becce F, Rajeswari M, Polson M, Guyen O et al. Arthritis & rheumatology (Hoboken, N.J.) (2019)
    100. [100]
      Can ultrasound differentiate acute erosive arthritis associated with osteomyelitis, rheumatoid arthritis, or gouty arthritis?Lu CH, Hsiao YF, Hsu HC, Ko YL, Lin TS, Chen LF et al. International journal of rheumatic diseases (2019)

    HemoChat

    by SPINAI

    Evidence-based clinical decision support powered by SNOMED-CT, Neo4j GraphRAG, and NASS/AO/NICE guidelines.

    ⚕ For clinical reference only. Not a substitute for professional judgment.

    © 2026 HemoChat. All rights reserved.
    Research·Pricing·Privacy & Terms·Refund·SNOMED-CT · NASS · AO Spine · NICE · GraphRAG