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Infectious Disease44 papers

Infection caused by Mycobacterium bovis

Last edited: 4/10/2026

Overview

Mycobacterium bovis is a species within the Mycobacterium tuberculosis complex that primarily infects cattle but poses a zoonotic risk to humans 1. M. bovis infection in cattle, known as bovine tuberculosis (bTB), is a significant public health concern 2.

Diagnosis

Management

Special Populations

Key Recommendations

  • The pooled prevalence of M. bovis among human Mycobacterium tuberculosis complex isolates was 12.1% across all included studies, but significantly lower at 1.4% when considering only genotyping-based studies 1.
  • The overall prevalence of bTB in dairy cattle in China from 2010-2019 was estimated at 2.4% 2.
  • Prevalence of bTB in dairy cattle was lowest in 2017 or later (0.8%) and in Northwestern China (0.7%) 2.
  • Heifer cows had the highest prevalence of bTB (27.1%), and prevalence was higher in scale farming (3.7%) compared to free-range farming (1.7%) 2.
  • Prevalence of bTB in dairy cattle was highest in summer (4.0%) 2.

    • References

    1 Taye H, Alemu K, Mihret A, Wood JLN, Shkedy Z, Berg S et al.. Global prevalence of Mycobacterium bovis infections among human tuberculosis cases: Systematic review and meta-analysis. Zoonoses and public health 2021. link 2 Gong QL, Chen Y, Tian T, Wen X, Li D, Song YH et al.. Prevalence of bovine tuberculosis in dairy cattle in China during 2010-2019: A systematic review and meta-analysis. PLoS neglected tropical diseases 2021. link

    Original source

    1. [1]
      Global prevalence of Mycobacterium bovis infections among human tuberculosis cases: Systematic review and meta-analysis. — Taye H, Alemu K, Mihret A, Wood JLN, Shkedy Z, Berg S et al. Zoonoses and public health (2021)
    2. [2]
      Prevalence of bovine tuberculosis in dairy cattle in China during 2010-2019: A systematic review and meta-analysis. — Gong QL, Chen Y, Tian T, Wen X, Li D, Song YH et al. PLoS neglected tropical diseases (2021)
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