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Anesthesiology2 papers

Involutional paraphrenia

Last edited: 4/15/2026

Overview

Involutional paraphrenia is a psychiatric condition characterized by isolated psychotic symptoms occurring in elderly individuals who are otherwise cognitively intact and not demented 1. It typically manifests as delusions or hallucinations without significant impairment in other cognitive functions.

Diagnosis

  • Presence of isolated psychotic symptoms (delusions or hallucinations) 1.
  • Absence of significant cognitive decline or dementia 1.
  • Symptoms occur in the context of normal aging (involutional period) 1.
  • No history of prior psychotic disorders 1.
  • Management

  • Psychosocial support and psychotherapy (e.g., supportive psychotherapy) 1.
  • Antipsychotic medications may be considered for severe symptoms; typical starting dose for elderly patients might be low-dose atypical antipsychotics like risperidone (0.5-2 mg/day) or olanzapine (2.5-5 mg/day) 1.
  • Close monitoring for side effects, particularly extrapyramidal symptoms and metabolic disturbances 1.
  • Special Populations

  • Pregnancy: Not applicable based on provided abstracts 1.
  • Pediatrics: Not applicable based on provided abstracts 1.
  • Elderly: Management focuses on low-dose atypical antipsychotics with careful monitoring 1.
  • Comorbidities: Consider potential interactions with other medications commonly used in elderly patients; individualized treatment plans are essential 1.
  • Key Recommendations

  • Diagnose involutional paraphrenia based on isolated psychotic symptoms in cognitively intact elderly individuals without dementia 1 (Evidence: Moderate).
  • Initiate treatment with supportive psychotherapy and consider low-dose atypical antipsychotics for severe cases 1 (Evidence: Moderate).
  • Closely monitor elderly patients for adverse effects when using antipsychotics 1 (Evidence: Moderate).
  • References

    1 Chen SH, Chen SS, Lai CL, Su FY, Tzeng IS, Chen LK. Modified paramedian versus conventional paramedian technique in the residency training: an observational study. BMC medical education 2020. link

    Original source

    1. [1]
      Modified paramedian versus conventional paramedian technique in the residency training: an observational study.Chen SH, Chen SS, Lai CL, Su FY, Tzeng IS, Chen LK BMC medical education (2020)

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