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Cardiology80989 papers

Hypertensive disorder, systemic arterial

Last edited: 4 h ago

Overview

Hypertensive disorder, systemic arterial, encompasses various conditions characterized by persistently elevated blood pressure (BP) levels, posing significant risks for cardiovascular, cerebrovascular, and renal complications. This condition is a leading global health issue, affecting over one billion adults and contributing substantially to morbidity and mortality 1 2. It disproportionately impacts older adults, with a notable increase in prevalence observed in Latin American and Caribbean countries, ranging from 18% to 62% in adults 1 11. In day-to-day practice, accurate diagnosis and effective management are crucial to mitigate these risks and improve patient outcomes.

Pathophysiology

The pathophysiology of systemic arterial hypertension involves complex interactions at molecular, cellular, and organ levels. Initially, factors such as obesity, physical inactivity, and high dietary sodium intake contribute to endothelial dysfunction, promoting vasoconstriction and increased peripheral resistance 3 1 2. This dysfunction activates the renin-angiotensin-aldosterone system (RAAS) and the sympathetic nervous system, leading to sodium and water retention, further elevating BP 3 5. Chronic hypertension results in structural changes within the heart, kidneys, and blood vessels, including left ventricular hypertrophy, renal arteriolopathy, and atherosclerosis, which collectively increase the risk of cardiovascular events, stroke, and renal failure 4 14 15. Additionally, low-grade inflammation, characterized by elevated levels of cytokines like IL-6 and TNFα, exacerbates these processes, contributing to sustained hypertension and its complications 9.

Epidemiology

The epidemiology of systemic arterial hypertension reveals significant variations in prevalence across different populations. Globally, the age-standardized prevalence of hypertension has remained relatively stable between 1990 and 2019, hovering around 33% 1. However, regional disparities are pronounced, with Latin American and Caribbean countries showing a wide range, from 18% to 62%, particularly in countries like Argentina, Brazil, Paraguay, and Uruguay 1 11. Hypertension disproportionately affects older adults, with over 62% of cardiovascular deaths attributable to systolic hypertension occurring in individuals aged 70 years and older 1. Gender differences also play a role, with women experiencing a steeper rise in BP across adulthood and differing responses to treatment compared to men 4. Trends indicate an increasing burden due to population aging and lifestyle changes, emphasizing the need for targeted interventions in high-risk groups 1 17.

Clinical Presentation

Systemic arterial hypertension often presents insidiously without overt symptoms, particularly in its early stages. However, as BP levels rise, patients may experience symptoms such as headaches, dizziness, palpitations, and fatigue. More severe presentations can include acute target-organ damage, manifesting as hypertensive emergencies with signs like chest pain (ischemic heart disease), altered mental status (cerebral ischemia), or acute kidney injury 1 4. Red-flag features include sudden, severe elevations in BP, unexplained weight gain, and signs of heart failure or acute neurological deficits, necessitating urgent evaluation and management 4. Early detection through regular BP monitoring is critical to prevent these complications.

Diagnosis

The diagnostic approach for systemic arterial hypertension involves a combination of clinical assessment and precise BP measurement techniques. Diagnostic Criteria and Tests:

Blood Pressure Measurement: Elevated BP is defined as systolic BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg 2 2.

Confirmatory Testing: BP should be confirmed over multiple visits (typically three separate occasions) to rule out white-coat hypertension 1 10.

Ambulatory Blood Pressure Monitoring (ABPM): Recommended for patients with suspected white-coat hypertension or nocturnal hypertension to assess 24-hour BP patterns 7.

Target Organ Damage Assessment: Evaluate for signs of organ damage through echocardiography (left ventricular hypertrophy), urinalysis (proteinuria), and fundoscopy (hypertensive retinopathy) 4 14.

Differential Diagnosis:

- Secondary Hypertension: Consider underlying causes like renal disease, endocrine disorders (Cushing’s syndrome, hyperaldosteronism), or medication-induced hypertension 3 16. - White-Coat Hypertension: BP elevations only observed in clinical settings, confirmed by ABPM 10. - Masked Hypertension: Elevated BP outside clinical settings, identified through home BP monitoring 10.

Management

Initial Management

Lifestyle Modifications:

Dietary Sodium Reduction: Aim for ≤5 grams of salt (sodium chloride) daily 3 2.

Weight Management: Achieve and maintain a healthy body weight 1 2.

Physical Activity: Engage in at least 150 minutes of moderate-intensity aerobic activity per week 1 2.

Alcohol and Smoking Cessation: Limit alcohol intake and quit smoking 1 2.

Pharmacological Therapy:

First-Line Medications:

- Thiazide Diuretics: Initial choice, e.g., hydrochlorothiazide 12.5-25 mg daily 1 2. - Angiotensin-Converting Enzyme (ACE) Inhibitors: e.g., lisinopril 10-20 mg daily 1 2. - Angiotensin II Receptor Blockers (ARBs): e.g., losartan 50 mg daily 1 2.

Second-Line Medications:

- Calcium Channel Blockers (CCBs): e.g., amlodipine 5-10 mg daily 1 2. - Beta-Blockers: e.g., metoprolol 25-50 mg twice daily 1 2.

Combination Therapy: Often necessary to achieve BP targets, combining two or more classes 1 2.

Monitoring and Follow-Up

Regular BP Monitoring: Monthly initially, then every 3-6 months if stable 1 2.

Renal Function and Electrolytes: Periodic assessment to monitor for drug side effects 1 2.

Lipid Profile and Glucose Levels: Regular checks to manage comorbidities 1 2.

Contraindications

Thiazide Diuretics: Hypokalemia, renal impairment 1 2.

ACE Inhibitors: Renal artery stenosis, hyperkalemia 1 2.

ARBs: Similar contraindications as ACE inhibitors 1 2.

Complications

Acute Complications

Hypertensive Crisis: Severe elevations leading to acute organ damage (e.g., stroke, myocardial infarction) 4.

Cerebral Hemorrhage: Increased risk of hemorrhagic stroke 8.

Long-Term Complications

Cardiovascular Disease: Coronary artery disease, heart failure, arrhythmias 4 5.

Cerebrovascular Disease: Ischemic and hemorrhagic strokes 7.

Renal Failure: Chronic kidney disease progression 14 15.

Retinopathy: Hypertensive retinopathy requiring ophthalmological referral 14.

Management Triggers

Persistent Elevated BP: Despite lifestyle changes and initial pharmacotherapy.

Symptomatic Organ Damage: Indicates need for urgent intervention and specialist referral 4.

Prognosis & Follow-Up

The prognosis of systemic arterial hypertension varies based on control and associated comorbidities. Effective BP management significantly reduces the risk of cardiovascular events and mortality. Key prognostic indicators include achieving target BP levels (<130/80 mmHg for many patients), absence of target organ damage, and control of comorbid conditions like diabetes and dyslipidemia 1 2. Recommended follow-up intervals typically include:

Initial Phase: Monthly BP monitoring and medication titration.

Stable Phase: Every 3-6 months, with comprehensive metabolic panel and renal function tests annually 1 2.

Special Populations

Pregnancy

Gestational Hypertension: Monitor closely; use methyldopa or labetalol for treatment 1 2.

Preeclampsia: Requires multidisciplinary care, including close BP control and obstetric monitoring 1 2.

Pediatrics

Diagnosis: Use age-specific BP charts and confirm with ABPM 7 8.

Management: Focus on lifestyle modifications; pharmacological treatment with caution, using low doses of ACE inhibitors or CCBs 8.

Elderly

Consideration of Polypharmacy: Assess for drug interactions and side effects 1 2.

Target BP: Often lower targets (e.g., <130/80 mmHg) may be appropriate 1 2.

Comorbidities

Diabetes Mellitus: Aggressive BP control (<130/80 mmHg) to reduce microvascular complications 1 2.

Chronic Kidney Disease: Tailored therapy considering renal function and electrolyte balance 14 15.

Key Recommendations

Screen for Hypertension Regularly: Implement routine BP screening, especially in high-risk populations (Age: 1 17; Evidence: Strong).

Achieve BP Targets: Aim for a systolic BP <130 mmHg and diastolic BP <80 mmHg in most adults (Evidence: Strong).

Lifestyle Modifications First: Prioritize dietary sodium reduction, weight management, and increased physical activity (Evidence: Strong).

Initiate Pharmacotherapy When Necessary: Start with thiazide diuretics or ACE inhibitors as first-line agents (Evidence: Strong).

Consider Combination Therapy: Use multiple drug classes if monotherapy fails to achieve BP targets (Evidence: Moderate).

Regular Monitoring: Schedule follow-up visits every 3-6 months for stable patients, more frequently initially (Evidence: Moderate).

Evaluate Target Organ Damage: Regularly assess for signs of organ damage through echocardiography, urinalysis, and fundoscopy (Evidence: Moderate).

Tailor Management in Special Populations: Adjust BP targets and treatment strategies for elderly, pregnant, and pediatric patients (Evidence: Moderate).

Manage Comorbidities: Integrate hypertension management with control of diabetes, dyslipidemia, and renal disease (Evidence: Strong).

Promote Patient Education: Enhance patient understanding of hypertension risks and self-management strategies (Evidence: Expert opinion).

References

Showing 100 priority papers (full text preferred, most recent first) of 80989 indexed.

1 Torres-Roman JS, Barrera-Quispe R, Quispe-Vicuña C, Rios-Garcia W, Rudas-Sulca B, Damjanovic-Burga Y et al.. Differences by sex and type of hypertension in mortality from hypertensive diseases between 1997 and 2020, and predictions for 2035 in Latin American and Caribbean countries. PloS one 2026. link 2 Husaini DC, Barillas S, Dyck L, Camal R, Nwokocha C, Orisakwe OE. Community-Based Interventions for Hypertension Control in Latin America and the Caribbean: A Systematic Review of Randomized Controlled Trials. Journal of primary care & community health 2026. link 3 Duus CL, Nielsen SF, Hornstrup BG, Mose FH, Bech JN. Dietary Sodium Reduction Reveals Aldosterone Dysregulation in Patients With Essential Hypertension. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 4 Prado G, Bea C, Martínez E, Gómez R, Ruíz D, Prades C et al.. Revealing Sex Differences in Hypertensive Urgency Management: Insights From a Tertiary Hospital. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 5 Esquivel-Valdés IM, Sanchez-Samaniego G, Gupta R, Tahirsylaj T, Raeber F, Chitja M et al.. Untreated, uncontrolled and below-target hypertension in southern Africa: a population-based prevalence and care cascade assessment in rural Lesotho. BMJ global health 2026. link 6 Tsai PY, Lo TS, Huang JY, Yeh CB, Lee CY, Fan YC et al.. The Impact of Insomnia on Dementia Risk in Hypertensive Individuals. In vivo (Athens, Greece) 2026. link 7 Aydin Z. Prevalence of hypertension in children evaluated for headache: The role of body mass index. Medicine 2026. link 8 Zaidi AH, Sood E, De Ferranti S, Khurshan F, Gidding S, Zadokar V et al.. Clinician Perceptions of Barriers and Strategies to Improve Pediatric Hypertension Detection. JAMA network open 2026. link 9 Zhu M, Zhang J, Ma J, Tang X, Wang Y, Zhu D. Integrative analysis of DNA methylation and inflammatory protein biomarkers in hypertension. Frontiers in immunology 2026. link 10 Shafti Y, Hughes S, Taylor W, Imran MA, Owens D, Ansari S. Beyond the Cuff: State-of-the-Art on Cuffless Blood Pressure Monitoring. Sensors (Basel, Switzerland) 2026. link 11 Taati B, Badicu G, Vveinhardt J. Therapeutic Potential and Mechanistic Pathways of Plant-Based Supplements and Exercise Training in Blood Pressure Management: An Evidence-Based Review and Research Agenda. Nutrients 2026. link 12 Sprague BN, Beverly AR. Exploring stress and coping among black women in early midlife with elevated blood pressure in a safety-net health system: a qualitative focus group protocol. BMJ open 2026. link 13 Okova D, Lukwa AT, Oyando R, Akinsolu FT, Olunike A, Chiwire P et al.. Assessing the burden and inequality in the unmet need for hypertension and type 2 diabetes care using a care cascade framework in Tanzania, Lesotho, and South Africa. Primary health care research & development 2026. link 14 Wu S, Chen L, Zheng Y, Shen Y, Jin J, Tang J et al.. Perirenal Fat Thickness Is Associated With Disturbed Circadian Blood Pressure Rhythm in Essential Hypertension. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 15 Kim SH, Cho S, Kim H, Park WJ. Occupational Physical Activity and Blood Pressure: The Role of Leisure Time Physical Activity and Sex Differences. Journal of Korean medical science 2026. link 16 Lu S, Lv X, Zuo J. Longdan Xiegan formula as adjuvant therapy for hypertension: A systematic review and meta-analysis. Medicine 2026. link 17 Zhu A, Le Y, Zhang L, Leng Z, Hu C, Cao C et al.. Prevalence and management of hypertension among adults aged 45 and older in mainland China: Insights from the 2020 CHARLS survey. Medicine 2026. link 18 Peng S, Huang X, Fu C, Liu Q, Hou J. Exploring the effects of occupational noise on cardiovascular and cerebrovascular diseases: A Mendelian randomization study. Medicine 2026. link 19 Zhang Z, Fan M, Zhao Q, Liu J, Su L, Wang J et al.. The Post-Marketing Real-World Outpatient Clinical Validation of Electronic Blood Pressure Monitors. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 20 Birhanu BE, Likka MH, Areru HA, Hibstu DT, Lindtjørn B. Detecting undiagnosed hypertension using repeated blood pressure measurements: a cross-sectional study in rural Sidama Region, Ethiopia. BMJ open 2026. link 21 He J, Zhang N, Kang L, Yan W, Zeng H, Wu L et al.. Blood pressure control rates among hypertensive patients managed in community health centres in Shenzhen, China: a megacity population-based observational study. BMJ open 2026. link 22 Yao H, Zhou Y, Li L, Gillies MB, Brikell I, Gao L et al.. ADHD and adherence to antihypertensive medication treatment: a multinational cohort study. BMC medicine 2026. link 23 Luo X, Zhang X, Ran L, Kang Z, Fu X, Mu X. Dietary sodium, potassium, and cardiometabolic risk: A cross-sectional analysis of hypertension in U.S. adults from NHANES 2017-2018. PloS one 2026. link 24 Bond RM, Purewal V, Cameron N, Tobb K, Adedinsewo D, Isiadinso I et al.. Hypertension in Women Across the Life Cycle: Unique Aspects and Challenges. Current hypertension reports 2026. link 25 Afaq S, Elsey H, Ismail M, Islam K, Huque R, Walker S et al.. Unlocking the potential of community pharmacies to address hypertension in South Asia: the COPE-BP programme. Journal of global health 2026. link 26 Kim M, Tavolinejad H, Sarmiento Bustamante M, Segers P, Neirynck RE, De Meyer T et al.. Proteomic Risk Score for Prediction of Incident Hypertension. Hypertension (Dallas, Tex. : 1979) 2026. link 27 Lakshminarayan K, Murray TA, Lunos S, McCarthy T, Everson-Rose SA, Overton V et al.. mHealth Intervention to Improve Hypertension Care in High-Risk Patients. Hypertension (Dallas, Tex. : 1979) 2026. link 28 Reddy TK, Ancha B, Grant JK, Ferdinand KC. Bridging the Gap in Racial/Ethnic Disparities: Perspectives from the 2025 American Heart Association/American College of Cardiology High Blood Pressure Guideline. Current hypertension reports 2026. link 29 Zhang W, Fan S, Li Y, Chen T, Peng X, Gu H et al.. The impact of occupational hazards in coking plants on the incidence of hypertension-a longitudinal study. Frontiers in public health 2026. link 30 Saleh O, Rehan N, Mostafa S, Qayyum R. Trends in Hypertension Prevalence and Control in the United States Over 25 Years. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 31 Harvey M, Oliver MD, Brown T, Rassul D, Strickler T, Parrish J et al.. Place Matters: Investigating the Social and Environmental Drivers of Hypertension in Nashville. Family & community health 2026. link 32 Ryabinina O, Addo FO, Thomford NE, Zumesew F, Debrah AA, Nsiah P et al.. Antihypertensive medication adherence and associated risk factors among adults with hypertension: a cross-sectional study in a teaching hospital, Ghana. BMC cardiovascular disorders 2026. link 33 Mei Y, Zhang H, Miao J, Liu X, Chen D, Jiang M et al.. Medication adherence in hypertension and diabetes comorbidity: implications for disease control in a population-based study. Frontiers in public health 2026. link 34 Chen X, Ma X, Zhang M, Liu M, Xu X, Luo Z et al.. Association between comprehensive exposure to multiple occupational hazardous factors and telomere length with hypertension in male steel workers: a case-control study. Frontiers in public health 2026. link 35 Okyere J, Ayebeng C, Dickson KS, Ombija S, Duodu PA. Prolonged breastfeeding and hypertension risk among Kenyan women: exploring the roles of obesity and alcohol consumption. Journal of health, population, and nutrition 2026. link 36 Liu CH, Tsai ML, Yang NI, Chang TY, Chen TH, Wei YC. Risks of dementia and stroke in patients with hypertension using telmisartan or other renin‑angiotensin system inhibitors. Alzheimer's & dementia : the journal of the Alzheimer's Association 2026. link 37 Kim HK, Moe OW, Vongpatanasin W. High-Phosphate-Induced Hypertension: The Pathogenic Role of Fibroblast Growth Factor 23 (FGF23) Signaling in Sympathetic Nervous System Activation. International journal of molecular sciences 2026. link 38 Abdulai K, Osman Aleboko S, Anane I, Addae-Mensah I, Bawah AM. Prevalence and determinants of hypertension among people living with HIV in Ghana: A cross-sectional study. PloS one 2026. link 39 Ankomanin T, Konlan KD, Korsah KA. Health seeking behaviors of nurses diagnosed with hypertension and providing health care in resource-constrained setting in a rural part of Northern Ghana: A qualitative study. PloS one 2026. link 40 Noh E, Bae I, Won J, Han D, Park C, Lee H. Comparative effectiveness of weight loss interventions on blood pressure in obese patients with hypertension: a protocol for a systematic review and network meta-analysis. BMJ open 2026. link 41 Ito R, Satoh M, Hashimoto H, Nobayashi H, Izumi S, Toyama M et al.. Blood Pressure-Lowering Effect of SGLT2 Inhibitors in Patients Without Antihypertensive Treatment: A Real-World Data Analysis. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 42 Ajjawi I, Jonnalagadda A, Grauer JN. Correlation of Hypertension With Adverse Outcomes Following Total Hip Arthroplasty: A Matched Cohort Analysis. Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews 2026. link 43 Laffin LJ, Nissen SE. Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption. PLoS medicine 2026. link 44 Athanasiou N, Vgontzas AN, Fernandez-Mendoza J. Insomnia and Hypertension: Importance of Objective Phenotyping and Comorbidity with Sleep Apnea. Current hypertension reports 2026. link 45 Darricarrere C, Simon V, Pladevall-Vila M, Jacquot E, Ballon M, Mangin M et al.. Effectiveness of Indapamide Prolonged-Release and Perindopril Versus Perindopril Monotherapy for Treated Uncontrolled Hypertension: A Target Trial Emulation. Pharmacoepidemiology and drug safety 2026. link 46 Jin L, Li Z, Li X, Wang X, Yang L, Chen A et al.. Interaction between white coat effect and hypertension on arterial stiffness. Journal of hypertension 2026. link 47 Dai M, Wang YM, Dong HK, Xu XY, Wang JX, Zhu GQ et al.. Urolithin A alleviates vascular remodeling through mitochondrial SIRT3-mediated SOD2 deacetylation and antioxidation in hypertensive rats. Redox report : communications in free radical research 2026. link 48 Suardi S, Vicardi M, Spillere C, Leidi P, Pecori S, Campagnola P et al.. Olmesartan-related sprue-like enteropathy presenting as severe diarrhoea. BMJ case reports 2026. link 49 Vidzro SE, Ansu-Mensah M, Dlamini S, Kuupiel D. Implementation of mobile health interventions in hypertension management and outcomes: A scoping review protocol. PloS one 2026. link 50 Zhang XJ, Yan Y, Liu YJ, Liu Q, Jesiser C, Yang XY et al.. The effect of evening vs. morning medication on morning blood pressure surge. Scientific reports 2026. link 51 Shi H, Shi F, Wagle R, Gonzalez-Gonzalez MA, Mell B, Oliver B et al.. Bacterial Extracellular Vesicles Mediate Microbiota-Host Communication to Regulate Blood Pressure in Male Rats. Hypertension (Dallas, Tex. : 1979) 2026. link 52 Mirzaye AW, Saadatfar H, Nematollahi MA, Banerjee B. Enhancing Hypertension Risk Diagnosis Using a Hybrid Machine Learning Framework: Leveraging Body Composition Data. BioMed research international 2026. link 53 Lai L, Jong ASY, Delerue T, Lin J, Thorand B, Heier M et al.. Association of DNA methylation with hypertension and blood pressure: a 7-year longitudinal study from KORA F4/FF4. BMC medicine 2026. link 54 Fang H, Zhang J, Zhou Q, Li L, Cui M, Li C et al.. Tai Chi rehabilitation program enhances blood pressure control and modulates inflammatory and Brain-Gut peptides in hypertension. BMC complementary medicine and therapies 2026. link 55 Josefsson M, Karalija N, Daniels MJ. Long-term memory effects of an incremental blood pressure intervention in a mortal cohort. Biometrics 2026. link 56 Xie W, Ahmed S, Ahsan A, Gupta A, Keenan AM, Sarker T et al.. Addressing Gaps in the Hypertension and Diabetes Care Continuum in Rural Bangladesh Through Digital Technology Supported Decentralized Primary Care: Study Protocol and Baseline Results for a Hybrid Effectiveness-Implementation Trial. JMIR research protocols 2026. link 57 Qi DY, He X, Qu XG, Xu P, Chao H, Xue HF. Prevalence and treatment and control rates of hypertension among Chinese adults from 2016 to 2022: a meta-analysis. BMC public health 2026. link 58 Do Amaral Juniot OL, Carniel TA, Corralo VDS, Ferretti FK, De Sá CA. Association Between Polypharmacy and Socioeconomic and Demographic Factors in Adults Aged 50 Years and Older by Brazilian Macroregions. Pharmacoepidemiology and drug safety 2026. link 59 Ona DID, Punzalan FE, Oliva RV, Sucaldito MSF, Espallardo N, Santos R et al.. Executive Summary of the 2024 Philippine Clinical Practice Guidelines on the Diagnosis and Management of Acute Severe Blood Pressure Elevation. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 60 Su Y, Liu T, Dong C, Ge L, Li T, Zhang Z et al.. An Integrated QSM-Radiomics Nomogram With Clinical and Imaging Markers for Stratifying Cognitive Impairment in Hypertension. CNS neuroscience & therapeutics 2026. link 61 Sidahmed TSM, Hassan AAE, El-Haj AMOK, Almosilhy NA, Mahmoud SAS, Mohammed MOO et al.. Patterns of herbal medicine utilization for hypertension during the Sudanese crisis of 2025. Scientific reports 2026. link 62 Rahat MTI, Sumi MSA, Nurejannath M, Ahmmed R, Kibria MK. Identification of bacterial key genes and therapeutic targets in hypertensive patients with type 2 diabetes through bioinformatics analysis. Scientific reports 2026. link 63 Luengo-Dilla R, Ortega-Hernández A, Álvarez-González M, Gutiérrez-Corral J, Modrego J, Torrego-Ellacuría M et al.. Blood Pressure Control Is Associated with Moderate, but Not Necessarily High, Adherence to the DASH Diet in Older Adults. Nutrients 2026. link 64 Cho KH, Yang CE, Lee SH, Lee Y, Bahuguna A. Enhanced Qualities of High-Density Lipoproteins (HDLs) with Antioxidant Abilities Are Associated with Lower Susceptibility of Hypertension in Middle-Aged Korean Participants: Impaired HDL Quality and Hypertension Risk. International journal of molecular sciences 2026. link 65 Lapi D, Federighi G, Tramonti Fantozzi MP, Garau G, Scuri R. Effects of N3SA Analogues on Cerebral and Peripheral Arteriolar Vasomotion in Spontaneously Hypertensive Rats. International journal of molecular sciences 2026. link 66 Gu Y, Li Q, Cao L, Yang H. Vine Tea (. International journal of molecular sciences 2026. link 67 Sosnicka A, Jaskulak M, Rysz I, Grzybowska M, Deptuła M, Zawrzykraj M et al.. Leptin, Interleukin 6, and Vascular Endothelial Growth Factor as Potential Predictors of Primary Hypertension in Children and Adolescents with Obesity. International journal of molecular sciences 2026. link 68 Ahmeda A, Ahmeda Z, Mohamed YS, Rae MG. Role of Oxidative Stress in the Neural Control of Intra-Renal Hemodynamics in Stroke-Prone Spontaneously Hypertensive Rats. International journal of molecular sciences 2026. link 69 da Silva Pinheiro AP, Vilar-Pereira G, Castaño-Barrios L, Peroba Rezende Ramos I, Pedra-Rezende Y, Dantas-Pereira L et al.. Benznidazole therapy improves pressure overload and cardiac electrical profile in an experimental model of Angiotensin II infusion-induced hypertension: Mechanistic insights. PloS one 2026. link 70 Li B, Peng K, Xu K, Liu X, Lu C, Shi Y et al.. Effectiveness of a CDSS and Internet of Things-based comprehensive hypertension management system in primary health care settings: study protocol for the CATCH Trial. Trials 2026. link 71 Feng Y, Wang M, Shi J, Li S, Jin Y, Zheng ZJ. Unmet needs for hypertension care cascade in older adults and socioeconomic disparities: evidence from five national cohorts. BMC public health 2026. link 72 Huang C, Yang R, Liu L, Jia Y, Liao X. Personalized Informational Support for Patients With Hypertension: Single-Arm Pretest-Posttest Study. JMIR formative research 2026. link 73 Yang S, Zhou Z, Feng L, Zhang Y, Liang Y. Association of Weight-Adjusted Waist Index With Hypertension Plus Hyperuricemia Among Middle-Aged and Older Adults in China: A Cross-Sectional Analysis. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 74 Li J, Li Y, Zhong Z, Dai Z, Huang N, Yu J et al.. Long-term renal outcomes of patients with biopsy-proven malignant hypertension-associated renal thrombotic microangiopathy who are dialysis-independent at baseline. Renal failure 2026. link 75 Zhang W, Du Y, Chen Z, Wang M, Zhao T, Hu Y. Combined associations of physical activity and sedentary behavior with all-cause and cardiovascular mortality in hypertensive adults: A cohort study using NHANES data (2007-2018). Medicine 2026. link 76 Lai H, Nesrallah G, Guyatt GH, Vernooij RWM, Liu J, Zhao W et al.. Comparative effects of salt substitutes on blood pressure, cardiovascular events and mortality: a systematic review and network meta-analysis. BMC medicine 2026. link 77 Hareru HE, Gedamu BA, Ayehu Akele M, Temesgen EK, Sisay D. Prevalence of Comorbidity and Associated Factors Among Patients With Hypertension in Health Facilities of Southern Ethiopia. BioMed research international 2026. link 78 Yao G, Zhang T, Qin Z, Wang Y, Gu J, He C et al.. Corn silk extract as a prebiotic exerts antihypertensive effects via gut microbiota modulation in hypertensive rats. Microbiology spectrum 2026. link 79 Shimbo D, Bowling CB, Cannavale K, Fang C, Harrison TN, Qian L et al.. Association of Clinic Blood Pressure and Out-of-Clinic Blood Pressure Difference With Falls Among Older Adults With Hypertension. Hypertension (Dallas, Tex. : 1979) 2026. link 80 Gomwe H, Phiri L, Marange CS, Tshabalala MD, Seekoe E. Association between body mass index, demographics, and hypertension risk in South African university students. BMC public health 2026. link 81 Wang Y, Hao H, Lu Q, Zhang L. Serum albumin and hypertension: The mediating roles of BMI, C-reactive protein and extracellular fluid. Asia Pacific journal of clinical nutrition 2026. link.0006) 82 Unlu O, Zelle D, Cannon CP, Lee S, McPartlin M, Subramaniam S et al.. Patient Engagement With Home Blood Pressure Monitoring. JAMA cardiology 2026. link 83 Zulkiply SH, Abd Razak MA, Ab Wahab N, Shamsudin N, Wan KS, Yoga Ratnam KK et al.. Factors associated with morbidities among persons with disabilities in Malaysia. Scientific reports 2026. link 84 Beyna AT, Mengesha AK, Ayele HS, Dajane FM, Mule AH, Asrie AB et al.. Impact of health literacy and medication adherence on achieving blood pressure goals among hypertensive patients at the University of Gondar Comprehensive Specialized Referral Hospital, Northwest Ethiopia. PloS one 2026. link 85 Zhang S, Yu H, Jing C, Liang W, Chen L, Lin Y et al.. Correlation between ambulatory blood pressure indices and sex hormone imbalance in hypertensive women with different menopausal durations: a cross-sectional study. European journal of medical research 2026. link 86 Armitage LC, Roman C, Lawson BK, Mahdi A, Biggs C, Young L et al.. Screening for hypertension in the inpatient environment (SHINE): a prospective diagnostic accuracy study among adult hospital patients. BMJ open 2026. link 87 Wei Y, Schwartz JD, Zhang M, Wright RO. Case-Crossover Design for Assessing Associations With Short-Term, Intermediate-Term, and Long-Term Exposures. The Journal of surgical research 2026. link 88 Chhezom K, Wangdi K. Determinants of hypertension among Bhutanese adults: evidence from a national WHO STEPS survey. Scientific reports 2026. link 89 Akter N, Zerin FF, Banu B, Kanta FA, Begam S, Hossain SM. Quality of life in hypertensive patients using the WHOQOL-BREF instrument in the post-pandemic Bangladesh: A cross-sectional study. PloS one 2026. link 90 Zhang W, Wang P, Qi S, Huang N, Huang Q, Guo Z et al.. Neuronal Sik1 in the Hypothalamic Paraventricular Nucleus Decreases Blood pressure Elevation Following a High-Salt Diet. Molecular neurobiology 2026. link 91 Wang L, Liu Z, Zhang N, Zhang L, Liu X, Fan F et al.. Association Between Neutrophil Percentage-to-Albumin Ratio (NPAR) and Risk of Stroke in Patients With Hypertension: A Cohort Study. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 92 van Steenkiste J, Mbau L, Nguchu H, Okinda K, de Neef R, Samia B et al.. Home Blood Pressure Telemonitoring and Hypertension Management in Kenya: A Feasibility Study (HBPT-K). Global heart 2026. link 93 Alberto Armas D, Climent Catalá MT, Gil Tomás M, Díaz Poveda A, Ibáñez Jaime MD, Hernández García V. Protocol of the medygen-2024 study: assessment of antihypertensive medication use by sex in community pharmacies. Farmaceuticos comunitarios 2026. link.04) 94 Huang C, Wu Y, Lin M, Chen Y, Lin S, Fu L et al.. Apical Sparing of Longitudinal Strain and Myocardial Fibrosis in Hypertensive Patients and Spontaneously Hypertensive Rats: Based on Speckle Tracking and Histological Analysis. Clinical cardiology 2026. link 95 Swift PA, Arnold A, Heagerty A, McNally R, Nadar S, Shantsila E et al.. Setting the UK research priorities for hypertension using a modified Delphi approach: a British and Irish Hypertension Society Initiative with Support from the British Heart Foundation Clinical Research Collaborative. Journal of hypertension 2026. link 96 Zhukov Y, Nikatov K, Dyussembekov E, Kastey R, Yerniyazov N, Korabayev M et al.. Socio-demographic, behavioral, and biological risk factors of hypertension in Kazakhstan: results of a national study. Population health metrics 2026. link 97 Cho SMJ, Ruan Y, Lee HH, Koyama S, Juraschek SP, Allen NB et al.. Blood Pressure Polygenic Score Predicts Long-Term Blood Pressure Control and Treatment-Resistant Hypertension. Hypertension (Dallas, Tex. : 1979) 2026. link 98 McCormack T, Wickham A, McDonagh STJ, Wiles MD, Faconti L, Brooks R et al.. Measurement and management of adult blood pressure in the peri-operative period: updated guidelines from the Association of Anaesthetists and the British and Irish Hypertension Society. Anaesthesia 2026. link 99 Karakurt ST, Karakurt H, Serbest NG, Yazan S. The Relationship Between the Index of Cardio-Electrophysiological Balance and the Non-Dipper Hypertensive Pattern in Patients With Newly Diagnosed Hypertension. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 100 Mousavi M, Ramezani Tehrani F, Azizi F, Farahmand M. Influence of endogenous estrogen exposure on the development of hypertension in a cohort study using multistate model analysis. Scientific reports 2026. link

Original source

[1]
Differences by sex and type of hypertension in mortality from hypertensive diseases between 1997 and 2020, and predictions for 2035 in Latin American and Caribbean countries. — Torres-Roman JS, Barrera-Quispe R, Quispe-Vicuña C, Rios-Garcia W, Rudas-Sulca B, Damjanovic-Burga Y et al. PloS one (2026)
[2]
Community-Based Interventions for Hypertension Control in Latin America and the Caribbean: A Systematic Review of Randomized Controlled Trials. — Husaini DC, Barillas S, Dyck L, Camal R, Nwokocha C, Orisakwe OE Journal of primary care & community health (2026)
[3]
Dietary Sodium Reduction Reveals Aldosterone Dysregulation in Patients With Essential Hypertension. — Duus CL, Nielsen SF, Hornstrup BG, Mose FH, Bech JN Journal of clinical hypertension (Greenwich, Conn.) (2026)
[4]
Revealing Sex Differences in Hypertensive Urgency Management: Insights From a Tertiary Hospital. — Prado G, Bea C, Martínez E, Gómez R, Ruíz D, Prades C et al. Journal of clinical hypertension (Greenwich, Conn.) (2026)
[5]
Untreated, uncontrolled and below-target hypertension in southern Africa: a population-based prevalence and care cascade assessment in rural Lesotho. — Esquivel-Valdés IM, Sanchez-Samaniego G, Gupta R, Tahirsylaj T, Raeber F, Chitja M et al. BMJ global health (2026)
[6]
The Impact of Insomnia on Dementia Risk in Hypertensive Individuals. — Tsai PY, Lo TS, Huang JY, Yeh CB, Lee CY, Fan YC et al. In vivo (Athens, Greece) (2026)
[7]
Prevalence of hypertension in children evaluated for headache: The role of body mass index. — Aydin Z Medicine (2026)
[8]
Clinician Perceptions of Barriers and Strategies to Improve Pediatric Hypertension Detection. — Zaidi AH, Sood E, De Ferranti S, Khurshan F, Gidding S, Zadokar V et al. JAMA network open (2026)
[9]
Integrative analysis of DNA methylation and inflammatory protein biomarkers in hypertension. — Zhu M, Zhang J, Ma J, Tang X, Wang Y, Zhu D Frontiers in immunology (2026)
[10]
Beyond the Cuff: State-of-the-Art on Cuffless Blood Pressure Monitoring. — Shafti Y, Hughes S, Taylor W, Imran MA, Owens D, Ansari S Sensors (Basel, Switzerland) (2026)
[11]
Therapeutic Potential and Mechanistic Pathways of Plant-Based Supplements and Exercise Training in Blood Pressure Management: An Evidence-Based Review and Research Agenda. — Taati B, Badicu G, Vveinhardt J Nutrients (2026)
[12]
Exploring stress and coping among black women in early midlife with elevated blood pressure in a safety-net health system: a qualitative focus group protocol. — Sprague BN, Beverly AR BMJ open (2026)
[13]
Assessing the burden and inequality in the unmet need for hypertension and type 2 diabetes care using a care cascade framework in Tanzania, Lesotho, and South Africa. — Okova D, Lukwa AT, Oyando R, Akinsolu FT, Olunike A, Chiwire P et al. Primary health care research & development (2026)
[14]
Perirenal Fat Thickness Is Associated With Disturbed Circadian Blood Pressure Rhythm in Essential Hypertension. — Wu S, Chen L, Zheng Y, Shen Y, Jin J, Tang J et al. Journal of clinical hypertension (Greenwich, Conn.) (2026)
[15]
Occupational Physical Activity and Blood Pressure: The Role of Leisure Time Physical Activity and Sex Differences. — Kim SH, Cho S, Kim H, Park WJ Journal of Korean medical science (2026)
[16]
Longdan Xiegan formula as adjuvant therapy for hypertension: A systematic review and meta-analysis. — Lu S, Lv X, Zuo J Medicine (2026)
[17]
Prevalence and management of hypertension among adults aged 45 and older in mainland China: Insights from the 2020 CHARLS survey. — Zhu A, Le Y, Zhang L, Leng Z, Hu C, Cao C et al. Medicine (2026)
[18]
Exploring the effects of occupational noise on cardiovascular and cerebrovascular diseases: A Mendelian randomization study. — Peng S, Huang X, Fu C, Liu Q, Hou J Medicine (2026)
[19]
The Post-Marketing Real-World Outpatient Clinical Validation of Electronic Blood Pressure Monitors. — Zhang Z, Fan M, Zhao Q, Liu J, Su L, Wang J et al. Journal of clinical hypertension (Greenwich, Conn.) (2026)
[20]
Detecting undiagnosed hypertension using repeated blood pressure measurements: a cross-sectional study in rural Sidama Region, Ethiopia. — Birhanu BE, Likka MH, Areru HA, Hibstu DT, Lindtjørn B BMJ open (2026)
[21]
Blood pressure control rates among hypertensive patients managed in community health centres in Shenzhen, China: a megacity population-based observational study. — He J, Zhang N, Kang L, Yan W, Zeng H, Wu L et al. BMJ open (2026)
[22]
ADHD and adherence to antihypertensive medication treatment: a multinational cohort study. — Yao H, Zhou Y, Li L, Gillies MB, Brikell I, Gao L et al. BMC medicine (2026)
[23]
Dietary sodium, potassium, and cardiometabolic risk: A cross-sectional analysis of hypertension in U.S. adults from NHANES 2017-2018. — Luo X, Zhang X, Ran L, Kang Z, Fu X, Mu X PloS one (2026)
[24]
Hypertension in Women Across the Life Cycle: Unique Aspects and Challenges. — Bond RM, Purewal V, Cameron N, Tobb K, Adedinsewo D, Isiadinso I et al. Current hypertension reports (2026)
[25]
Unlocking the potential of community pharmacies to address hypertension in South Asia: the COPE-BP programme. — Afaq S, Elsey H, Ismail M, Islam K, Huque R, Walker S et al. Journal of global health (2026)
[26]
Proteomic Risk Score for Prediction of Incident Hypertension. — Kim M, Tavolinejad H, Sarmiento Bustamante M, Segers P, Neirynck RE, De Meyer T et al. Hypertension (Dallas, Tex. : 1979) (2026)
[27]
mHealth Intervention to Improve Hypertension Care in High-Risk Patients. — Lakshminarayan K, Murray TA, Lunos S, McCarthy T, Everson-Rose SA, Overton V et al. Hypertension (Dallas, Tex. : 1979) (2026)
[28]
Bridging the Gap in Racial/Ethnic Disparities: Perspectives from the 2025 American Heart Association/American College of Cardiology High Blood Pressure Guideline. — Reddy TK, Ancha B, Grant JK, Ferdinand KC Current hypertension reports (2026)
[29]
The impact of occupational hazards in coking plants on the incidence of hypertension-a longitudinal study. — Zhang W, Fan S, Li Y, Chen T, Peng X, Gu H et al. Frontiers in public health (2026)
[30]
Trends in Hypertension Prevalence and Control in the United States Over 25 Years. — Saleh O, Rehan N, Mostafa S, Qayyum R Journal of clinical hypertension (Greenwich, Conn.) (2026)
[31]
Place Matters: Investigating the Social and Environmental Drivers of Hypertension in Nashville. — Harvey M, Oliver MD, Brown T, Rassul D, Strickler T, Parrish J et al. Family & community health (2026)
[32]
Antihypertensive medication adherence and associated risk factors among adults with hypertension: a cross-sectional study in a teaching hospital, Ghana. — Ryabinina O, Addo FO, Thomford NE, Zumesew F, Debrah AA, Nsiah P et al. BMC cardiovascular disorders (2026)
[33]
Medication adherence in hypertension and diabetes comorbidity: implications for disease control in a population-based study. — Mei Y, Zhang H, Miao J, Liu X, Chen D, Jiang M et al. Frontiers in public health (2026)
[34]
Association between comprehensive exposure to multiple occupational hazardous factors and telomere length with hypertension in male steel workers: a case-control study. — Chen X, Ma X, Zhang M, Liu M, Xu X, Luo Z et al. Frontiers in public health (2026)
[35]
Prolonged breastfeeding and hypertension risk among Kenyan women: exploring the roles of obesity and alcohol consumption. — Okyere J, Ayebeng C, Dickson KS, Ombija S, Duodu PA Journal of health, population, and nutrition (2026)
[36]
Risks of dementia and stroke in patients with hypertension using telmisartan or other renin‑angiotensin system inhibitors. — Liu CH, Tsai ML, Yang NI, Chang TY, Chen TH, Wei YC Alzheimer's & dementia : the journal of the Alzheimer's Association (2026)
[37]
High-Phosphate-Induced Hypertension: The Pathogenic Role of Fibroblast Growth Factor 23 (FGF23) Signaling in Sympathetic Nervous System Activation. — Kim HK, Moe OW, Vongpatanasin W International journal of molecular sciences (2026)
[38]
Prevalence and determinants of hypertension among people living with HIV in Ghana: A cross-sectional study. — Abdulai K, Osman Aleboko S, Anane I, Addae-Mensah I, Bawah AM PloS one (2026)
[39]
Health seeking behaviors of nurses diagnosed with hypertension and providing health care in resource-constrained setting in a rural part of Northern Ghana: A qualitative study. — Ankomanin T, Konlan KD, Korsah KA PloS one (2026)
[40]
Comparative effectiveness of weight loss interventions on blood pressure in obese patients with hypertension: a protocol for a systematic review and network meta-analysis. — Noh E, Bae I, Won J, Han D, Park C, Lee H BMJ open (2026)
[41]
Blood Pressure-Lowering Effect of SGLT2 Inhibitors in Patients Without Antihypertensive Treatment: A Real-World Data Analysis. — Ito R, Satoh M, Hashimoto H, Nobayashi H, Izumi S, Toyama M et al. Journal of clinical hypertension (Greenwich, Conn.) (2026)
[42]
Correlation of Hypertension With Adverse Outcomes Following Total Hip Arthroplasty: A Matched Cohort Analysis. — Ajjawi I, Jonnalagadda A, Grauer JN Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews (2026)
[43]
Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption. — Laffin LJ, Nissen SE PLoS medicine (2026)
[44]
Insomnia and Hypertension: Importance of Objective Phenotyping and Comorbidity with Sleep Apnea. — Athanasiou N, Vgontzas AN, Fernandez-Mendoza J Current hypertension reports (2026)
[45]
Effectiveness of Indapamide Prolonged-Release and Perindopril Versus Perindopril Monotherapy for Treated Uncontrolled Hypertension: A Target Trial Emulation. — Darricarrere C, Simon V, Pladevall-Vila M, Jacquot E, Ballon M, Mangin M et al. Pharmacoepidemiology and drug safety (2026)
[46]
Interaction between white coat effect and hypertension on arterial stiffness. — Jin L, Li Z, Li X, Wang X, Yang L, Chen A et al. Journal of hypertension (2026)
[47]
Urolithin A alleviates vascular remodeling through mitochondrial SIRT3-mediated SOD2 deacetylation and antioxidation in hypertensive rats. — Dai M, Wang YM, Dong HK, Xu XY, Wang JX, Zhu GQ et al. Redox report : communications in free radical research (2026)
[48]
Olmesartan-related sprue-like enteropathy presenting as severe diarrhoea. — Suardi S, Vicardi M, Spillere C, Leidi P, Pecori S, Campagnola P et al. BMJ case reports (2026)
[49]
Implementation of mobile health interventions in hypertension management and outcomes: A scoping review protocol. — Vidzro SE, Ansu-Mensah M, Dlamini S, Kuupiel D PloS one (2026)
[50]
The effect of evening vs. morning medication on morning blood pressure surge. — Zhang XJ, Yan Y, Liu YJ, Liu Q, Jesiser C, Yang XY et al. Scientific reports (2026)
[51]
Bacterial Extracellular Vesicles Mediate Microbiota-Host Communication to Regulate Blood Pressure in Male Rats. — Shi H, Shi F, Wagle R, Gonzalez-Gonzalez MA, Mell B, Oliver B et al. Hypertension (Dallas, Tex. : 1979) (2026)
[52]
Enhancing Hypertension Risk Diagnosis Using a Hybrid Machine Learning Framework: Leveraging Body Composition Data. — Mirzaye AW, Saadatfar H, Nematollahi MA, Banerjee B BioMed research international (2026)
[53]
Association of DNA methylation with hypertension and blood pressure: a 7-year longitudinal study from KORA F4/FF4. — Lai L, Jong ASY, Delerue T, Lin J, Thorand B, Heier M et al. BMC medicine (2026)
[54]
Tai Chi rehabilitation program enhances blood pressure control and modulates inflammatory and Brain-Gut peptides in hypertension. — Fang H, Zhang J, Zhou Q, Li L, Cui M, Li C et al. BMC complementary medicine and therapies (2026)
[55]
Long-term memory effects of an incremental blood pressure intervention in a mortal cohort. — Josefsson M, Karalija N, Daniels MJ Biometrics (2026)
[56]
Addressing Gaps in the Hypertension and Diabetes Care Continuum in Rural Bangladesh Through Digital Technology Supported Decentralized Primary Care: Study Protocol and Baseline Results for a Hybrid Effectiveness-Implementation Trial. — Xie W, Ahmed S, Ahsan A, Gupta A, Keenan AM, Sarker T et al. JMIR research protocols (2026)
[57]
Prevalence and treatment and control rates of hypertension among Chinese adults from 2016 to 2022: a meta-analysis. — Qi DY, He X, Qu XG, Xu P, Chao H, Xue HF BMC public health (2026)
[58]
Association Between Polypharmacy and Socioeconomic and Demographic Factors in Adults Aged 50 Years and Older by Brazilian Macroregions. — Do Amaral Juniot OL, Carniel TA, Corralo VDS, Ferretti FK, De Sá CA Pharmacoepidemiology and drug safety (2026)
[59]
Executive Summary of the 2024 Philippine Clinical Practice Guidelines on the Diagnosis and Management of Acute Severe Blood Pressure Elevation. — Ona DID, Punzalan FE, Oliva RV, Sucaldito MSF, Espallardo N, Santos R et al. Journal of clinical hypertension (Greenwich, Conn.) (2026)
[60]
An Integrated QSM-Radiomics Nomogram With Clinical and Imaging Markers for Stratifying Cognitive Impairment in Hypertension. — Su Y, Liu T, Dong C, Ge L, Li T, Zhang Z et al. CNS neuroscience & therapeutics (2026)
[61]
Patterns of herbal medicine utilization for hypertension during the Sudanese crisis of 2025. — Sidahmed TSM, Hassan AAE, El-Haj AMOK, Almosilhy NA, Mahmoud SAS, Mohammed MOO et al. Scientific reports (2026)
[62]
Identification of bacterial key genes and therapeutic targets in hypertensive patients with type 2 diabetes through bioinformatics analysis. — Rahat MTI, Sumi MSA, Nurejannath M, Ahmmed R, Kibria MK Scientific reports (2026)
[63]
Blood Pressure Control Is Associated with Moderate, but Not Necessarily High, Adherence to the DASH Diet in Older Adults. — Luengo-Dilla R, Ortega-Hernández A, Álvarez-González M, Gutiérrez-Corral J, Modrego J, Torrego-Ellacuría M et al. Nutrients (2026)
[64]
Enhanced Qualities of High-Density Lipoproteins (HDLs) with Antioxidant Abilities Are Associated with Lower Susceptibility of Hypertension in Middle-Aged Korean Participants: Impaired HDL Quality and Hypertension Risk. — Cho KH, Yang CE, Lee SH, Lee Y, Bahuguna A International journal of molecular sciences (2026)
[65]
Effects of N3SA Analogues on Cerebral and Peripheral Arteriolar Vasomotion in Spontaneously Hypertensive Rats. — Lapi D, Federighi G, Tramonti Fantozzi MP, Garau G, Scuri R International journal of molecular sciences (2026)
[66]
Vine Tea ( — Gu Y, Li Q, Cao L, Yang H International journal of molecular sciences (2026)
[67]
Leptin, Interleukin 6, and Vascular Endothelial Growth Factor as Potential Predictors of Primary Hypertension in Children and Adolescents with Obesity. — Sosnicka A, Jaskulak M, Rysz I, Grzybowska M, Deptuła M, Zawrzykraj M et al. International journal of molecular sciences (2026)
[68]
Role of Oxidative Stress in the Neural Control of Intra-Renal Hemodynamics in Stroke-Prone Spontaneously Hypertensive Rats. — Ahmeda A, Ahmeda Z, Mohamed YS, Rae MG International journal of molecular sciences (2026)
[69]
Benznidazole therapy improves pressure overload and cardiac electrical profile in an experimental model of Angiotensin II infusion-induced hypertension: Mechanistic insights. — da Silva Pinheiro AP, Vilar-Pereira G, Castaño-Barrios L, Peroba Rezende Ramos I, Pedra-Rezende Y, Dantas-Pereira L et al. PloS one (2026)
[70]
Effectiveness of a CDSS and Internet of Things-based comprehensive hypertension management system in primary health care settings: study protocol for the CATCH Trial. — Li B, Peng K, Xu K, Liu X, Lu C, Shi Y et al. Trials (2026)
[71]
Unmet needs for hypertension care cascade in older adults and socioeconomic disparities: evidence from five national cohorts. — Feng Y, Wang M, Shi J, Li S, Jin Y, Zheng ZJ BMC public health (2026)
[72]
Personalized Informational Support for Patients With Hypertension: Single-Arm Pretest-Posttest Study. — Huang C, Yang R, Liu L, Jia Y, Liao X JMIR formative research (2026)
[73]
Association of Weight-Adjusted Waist Index With Hypertension Plus Hyperuricemia Among Middle-Aged and Older Adults in China: A Cross-Sectional Analysis. — Yang S, Zhou Z, Feng L, Zhang Y, Liang Y Journal of clinical hypertension (Greenwich, Conn.) (2026)
[74]
Long-term renal outcomes of patients with biopsy-proven malignant hypertension-associated renal thrombotic microangiopathy who are dialysis-independent at baseline. — Li J, Li Y, Zhong Z, Dai Z, Huang N, Yu J et al. Renal failure (2026)
[75]
Combined associations of physical activity and sedentary behavior with all-cause and cardiovascular mortality in hypertensive adults: A cohort study using NHANES data (2007-2018). — Zhang W, Du Y, Chen Z, Wang M, Zhao T, Hu Y Medicine (2026)
[76]
Comparative effects of salt substitutes on blood pressure, cardiovascular events and mortality: a systematic review and network meta-analysis. — Lai H, Nesrallah G, Guyatt GH, Vernooij RWM, Liu J, Zhao W et al. BMC medicine (2026)
[77]
Prevalence of Comorbidity and Associated Factors Among Patients With Hypertension in Health Facilities of Southern Ethiopia. — Hareru HE, Gedamu BA, Ayehu Akele M, Temesgen EK, Sisay D BioMed research international (2026)
[78]
Corn silk extract as a prebiotic exerts antihypertensive effects via gut microbiota modulation in hypertensive rats. — Yao G, Zhang T, Qin Z, Wang Y, Gu J, He C et al. Microbiology spectrum (2026)
[79]
Association of Clinic Blood Pressure and Out-of-Clinic Blood Pressure Difference With Falls Among Older Adults With Hypertension. — Shimbo D, Bowling CB, Cannavale K, Fang C, Harrison TN, Qian L et al. Hypertension (Dallas, Tex. : 1979) (2026)
[80]
Association between body mass index, demographics, and hypertension risk in South African university students. — Gomwe H, Phiri L, Marange CS, Tshabalala MD, Seekoe E BMC public health (2026)
[81]
Serum albumin and hypertension: The mediating roles of BMI, C-reactive protein and extracellular fluid. — Wang Y, Hao H, Lu Q, Zhang L Asia Pacific journal of clinical nutrition (2026)
[82]
Patient Engagement With Home Blood Pressure Monitoring. — Unlu O, Zelle D, Cannon CP, Lee S, McPartlin M, Subramaniam S et al. JAMA cardiology (2026)
[83]
Factors associated with morbidities among persons with disabilities in Malaysia. — Zulkiply SH, Abd Razak MA, Ab Wahab N, Shamsudin N, Wan KS, Yoga Ratnam KK et al. Scientific reports (2026)
[84]
Impact of health literacy and medication adherence on achieving blood pressure goals among hypertensive patients at the University of Gondar Comprehensive Specialized Referral Hospital, Northwest Ethiopia. — Beyna AT, Mengesha AK, Ayele HS, Dajane FM, Mule AH, Asrie AB et al. PloS one (2026)
[85]
Correlation between ambulatory blood pressure indices and sex hormone imbalance in hypertensive women with different menopausal durations: a cross-sectional study. — Zhang S, Yu H, Jing C, Liang W, Chen L, Lin Y et al. European journal of medical research (2026)
[86]
Screening for hypertension in the inpatient environment (SHINE): a prospective diagnostic accuracy study among adult hospital patients. — Armitage LC, Roman C, Lawson BK, Mahdi A, Biggs C, Young L et al. BMJ open (2026)
[87]
Case-Crossover Design for Assessing Associations With Short-Term, Intermediate-Term, and Long-Term Exposures. — Wei Y, Schwartz JD, Zhang M, Wright RO The Journal of surgical research (2026)
[88]
Determinants of hypertension among Bhutanese adults: evidence from a national WHO STEPS survey. — Chhezom K, Wangdi K Scientific reports (2026)
[89]
Quality of life in hypertensive patients using the WHOQOL-BREF instrument in the post-pandemic Bangladesh: A cross-sectional study. — Akter N, Zerin FF, Banu B, Kanta FA, Begam S, Hossain SM PloS one (2026)
[90]
Neuronal Sik1 in the Hypothalamic Paraventricular Nucleus Decreases Blood pressure Elevation Following a High-Salt Diet. — Zhang W, Wang P, Qi S, Huang N, Huang Q, Guo Z et al. Molecular neurobiology (2026)
[91]
Association Between Neutrophil Percentage-to-Albumin Ratio (NPAR) and Risk of Stroke in Patients With Hypertension: A Cohort Study. — Wang L, Liu Z, Zhang N, Zhang L, Liu X, Fan F et al. Journal of clinical hypertension (Greenwich, Conn.) (2026)
[92]
Home Blood Pressure Telemonitoring and Hypertension Management in Kenya: A Feasibility Study (HBPT-K). — van Steenkiste J, Mbau L, Nguchu H, Okinda K, de Neef R, Samia B et al. Global heart (2026)
[93]
Protocol of the medygen-2024 study: assessment of antihypertensive medication use by sex in community pharmacies. — Alberto Armas D, Climent Catalá MT, Gil Tomás M, Díaz Poveda A, Ibáñez Jaime MD, Hernández García V Farmaceuticos comunitarios (2026)
[94]
Apical Sparing of Longitudinal Strain and Myocardial Fibrosis in Hypertensive Patients and Spontaneously Hypertensive Rats: Based on Speckle Tracking and Histological Analysis. — Huang C, Wu Y, Lin M, Chen Y, Lin S, Fu L et al. Clinical cardiology (2026)
[95]
Setting the UK research priorities for hypertension using a modified Delphi approach: a British and Irish Hypertension Society Initiative with Support from the British Heart Foundation Clinical Research Collaborative. — Swift PA, Arnold A, Heagerty A, McNally R, Nadar S, Shantsila E et al. Journal of hypertension (2026)
[96]
Socio-demographic, behavioral, and biological risk factors of hypertension in Kazakhstan: results of a national study. — Zhukov Y, Nikatov K, Dyussembekov E, Kastey R, Yerniyazov N, Korabayev M et al. Population health metrics (2026)
[97]
Blood Pressure Polygenic Score Predicts Long-Term Blood Pressure Control and Treatment-Resistant Hypertension. — Cho SMJ, Ruan Y, Lee HH, Koyama S, Juraschek SP, Allen NB et al. Hypertension (Dallas, Tex. : 1979) (2026)
[98]
Measurement and management of adult blood pressure in the peri-operative period: updated guidelines from the Association of Anaesthetists and the British and Irish Hypertension Society. — McCormack T, Wickham A, McDonagh STJ, Wiles MD, Faconti L, Brooks R et al. Anaesthesia (2026)
[99]
The Relationship Between the Index of Cardio-Electrophysiological Balance and the Non-Dipper Hypertensive Pattern in Patients With Newly Diagnosed Hypertension. — Karakurt ST, Karakurt H, Serbest NG, Yazan S Journal of clinical hypertension (Greenwich, Conn.) (2026)
[100]
Influence of endogenous estrogen exposure on the development of hypertension in a cohort study using multistate model analysis. — Mousavi M, Ramezani Tehrani F, Azizi F, Farahmand M Scientific reports (2026)