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Neoplasm, benign — Clinical Guidelines

Overview

Benign neoplasms are non-malignant tumors that do not invade surrounding tissues or metastasize. They can arise from various tissues and organs, including those within the broad ligament and nipple ducts, though specific benign neoplasms like fibrothecoma and erosive adenomatosis are exceedingly rare 7 8.

Diagnosis

Clinical Presentation: Varied depending on location; may present with local symptoms or be asymptomatic 7 8.

Imaging: Utilized for initial assessment to identify mass characteristics 1.

Biopsy: Essential for definitive diagnosis; excisional biopsy often sufficient for benign lesions 4.

Histopathology: Critical for distinguishing benign neoplasms from malignant counterparts 4 8.

Management

Surgical Excision: Primary treatment for localized benign neoplasms to ensure complete removal 4 7.

Monitoring: Follow-up imaging or clinical exams recommended to ensure no recurrence 1.

No Specific Medication: Generally not required for benign neoplasms 1 4.

Special Populations

Pregnancy: No specific guidelines provided in abstracts; management typically conservative unless symptomatic 1.

Pediatrics: Management similar to adults, with emphasis on minimal intervention 1.

Elderly: Consider comorbidities and overall health status when planning surgical interventions 1.

Comorbidities: Tailor surgical approach based on patient's overall health condition 1.

Key Recommendations

Definitive Diagnosis Requires Histopathological Examination: Excisional biopsy is often adequate for benign neoplasms 4 (Evidence: Strong).

Surgical Excision is the Primary Treatment: Ensures complete removal and reduces recurrence risk 4 7 (Evidence: Strong).

Regular Follow-Up is Essential: Monitor for recurrence post-excision, especially in high-risk cases 1 (Evidence: Moderate).

References

1 Morgan DE, Zarzour JG, Millette N, Galgano SJ, Smith EN, Canon CL. Accelerated Fellowships Applicable Across all Subspecialty Areas of Diagnostic Radiology as a Catalyst for Academic Recruitment. Academic radiology 2023. link 2 Pfeifer CM, Reddy N, Burton KR, Griffith B, Bazylewicz MP, Pakkal MV et al.. The Evolving Status of Fellowships and Mini-Fellowships in Diagnostic Radiology: A Survey of Program Directors and Chief Residents. Academic radiology 2021. link 3 Agarwal A, Singh MR. Service Quality and Patient Satisfaction: An Exploratory Study of Pathology Laboratories in Jaipur. Hospital topics 2016. link 4 Twaij S, Shafi A, Marshall T, Jabir M. Caruncular neurofibroma not associated with neurofibromatosis. BMJ case reports 2013. link 5 Christopher MM, Hotz CS. Cytologic diagnosis: expression of probability by clinical pathologists. Veterinary clinical pathology 2004. link 6 Stempsey WE. The virtuous pathologist. An ethical basis for laboratory medicine. American journal of clinical pathology 1989. link 7 Merino MJ, LiVolsi VA, Trepeta RW. Fibrothecoma of the broad ligament. Diagnostic gynecology and obstetrics 1980. link 8 Lewis HM, Ovitz ML, Golitz LE. Erosive adenomatosis of the nipple. Archives of dermatology 1976. link

Neoplasm, benign