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Dermatology16 papers

Basal cell carcinoma - micronodular

Last edited: 4/10/2026

Overview

Micronodular basal cell carcinoma (BCC) is a subtype of BCC characterized by small, discrete nests of basaloid cells within the dermis 1. It is considered a more aggressive subtype with a higher risk of recurrence and deeper invasion compared to other BCC subtypes 1.

Diagnosis

  • Histopathological examination is required for definitive diagnosis 1.
  • Key features include small nests of basaloid cells with peripheral palisading and stromal retraction 1.

    • Management

  • Surgical excision with adequate margins is the primary treatment modality 1.
  • Mohs micrographic surgery may be considered for micronodular BCC due to its aggressive nature and potential for subclinical spread 1.
  • Other treatment options may include topical therapies or radiation, particularly for unresectable or recurrent cases 1.

    • Key Recommendations

  • Histopathological examination is essential for the diagnosis of micronodular basal cell carcinoma 1. (Evidence: Moderate)
  • Surgical excision with appropriate margins is the recommended first-line treatment for micronodular basal cell carcinoma 1. (Evidence: Moderate)
  • Mohs micrographic surgery should be considered for micronodular basal cell carcinoma due to its aggressive behavior 1. (Evidence: Moderate)

    • References

    1 Bhadale RS, Londhe VY. A systematic review of carbohydrate-based microneedles: current status and future prospects. Journal of materials science. Materials in medicine 2021. link

    Original source

    1. [1]
      A systematic review of carbohydrate-based microneedles: current status and future prospects. — Bhadale RS, Londhe VY Journal of materials science. Materials in medicine (2021)
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