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Infectious Disease1 paper

Primary herpes simplex infection of genitalia

Last edited: 4/10/2026

Overview

Genital herpes is a common sexually transmitted infection globally 1. Early recognition and treatment are crucial for reducing illness duration and preventing complications such as urinary retention, meningism, or severe systemic illness 1.

Diagnosis

  • Early recognition and initiation of therapy are key 1.
  • Diagnostic strategies are covered in the guideline 1.
  • Management

  • Antiviral therapy is recommended 1.
  • Management strategies for recurrent genital herpes are covered 1.
  • Special Populations

  • Management of genital herpes during pregnancy is covered 1.
  • Management of genital herpes in coinfection with human immunodeficiency virus is covered 1.
  • Key Recommendations

  • Early recognition and initiation of therapy may reduce the duration of illness or avoid hospitalization with complications 1. (Evidence: Expert opinion)
  • The guideline recommends strategies for diagnosis, management, and follow-up of genital herpes 1. (Evidence: Expert opinion)
  • Strategies for minimizing transmission of genital herpes are recommended 1. (Evidence: Expert opinion)
  • References

    1 Patel R, Moran B, Clarke E, Geretti AM, Lautenschlager S, Green J et al.. 2024 European guidelines for the management of genital herpes. Journal of the European Academy of Dermatology and Venereology : JEADV 2025. link

    Original source

    1. [1]
      2024 European guidelines for the management of genital herpes.Patel R, Moran B, Clarke E, Geretti AM, Lautenschlager S, Green J et al. Journal of the European Academy of Dermatology and Venereology : JEADV (2025)

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