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Cardiology30 papers

Rift valley fever

Last edited: 4/23/2026

Overview

Rift Valley fever (RVF) is a viral zoonosis caused by the RVF virus, primarily affecting livestock but also humans, manifesting with febrile, encephalitic, and hemorrhagic syndromes, and can include severe ocular complications 1.

Diagnosis

  • Serological diagnosis (IgM/IgG antibodies) is crucial 1.
  • Ocular manifestations include bilateral macular, paramacular, and extramacular retinal lesions, often with hemorrhage, edema, vasculitis, retinitis, and vascular occlusion, identifiable via color photography and fluorescein angiography 1.
  • Management

  • Supportive care is essential for managing systemic manifestations 1.
  • Specific antiviral treatments are not detailed in the provided abstracts; focus on symptom management and monitoring 1.
  • For ocular complications, close ophthalmological follow-up is necessary, though specific therapeutic interventions are not specified in the abstracts 1.
  • Special Populations

  • No specific data provided regarding pregnancy, pediatrics, elderly, or comorbidities in the given abstracts 1.
  • Key Recommendations

  • Conduct serological testing (IgM/IgG antibodies) for definitive diagnosis of RVF 1.
  • Implement comprehensive supportive care measures for systemic RVF symptoms 1.
  • Provide close ophthalmological monitoring for patients with ocular manifestations due to potential permanent visual impairment 1 (Evidence: Moderate).
  • References

    1 Siam AL, Meegan JM, Gharbawi KF. Rift Valley fever ocular manifestations: observations during the 1977 epidemic in Egypt. The British journal of ophthalmology 1980. link

    Original source

    1. [1]
      Rift Valley fever ocular manifestations: observations during the 1977 epidemic in Egypt.Siam AL, Meegan JM, Gharbawi KF The British journal of ophthalmology (1980)

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