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Musculoskeletal257 papers

Postconcussion syndrome

Last edited: 4/14/2026

Overview

Postconcussion syndrome (PCS) refers to the persistence of symptoms beyond 4 weeks following a concussion, affecting cognitive, emotional, and physical functioning 14.

Diagnosis

  • Symptoms persist for >4 weeks post-injury 14.
  • No specific diagnostic tests; clinical assessment is key 14.
  • Grading systems often rely on symptom severity and functional impairment 1.
  • Management

  • First-line treatments:
  • - Early information and advice 1. - Graduated physical exercise 1. - Vestibular rehabilitation 1. - Manual treatment of neck and back 1. - Oculomotor vision treatment 1.
  • Adjunctive treatments:
  • - Psychological interventions 1. - Interdisciplinary coordinated rehabilitation programs 1.

    Special Populations

  • Pediatrics: High economic burden with costs including sports medicine visits, therapy, and tutoring, totaling approximately $3557 per patient 2.
  • Comorbidities: No specific management details provided in abstracts 124.
  • Key Recommendations

  • Implement early information and advice for patients with persistent postconcussion symptoms (Evidence: Moderate 1).
  • Incorporate graded physical exercise as a core component of rehabilitation (Evidence: Moderate 1).
  • Utilize interdisciplinary coordinated rehabilitation programs to address multifaceted symptoms (Evidence: Moderate 1).
  • Consider vestibular rehabilitation and manual therapy for musculoskeletal symptoms (Evidence: Moderate 1).
  • Psychological treatments should be integrated into comprehensive care plans (Evidence: Moderate 1).
  • Monitor and manage economic impacts, particularly in pediatric populations, through targeted therapeutic interventions (Evidence: Strong 2).
  • References

    1 Rytter HM, Graff HJ, Henriksen HK, Aaen N, Hartvigsen J, Hoegh M et al.. Nonpharmacological Treatment of Persistent Postconcussion Symptoms in Adults: A Systematic Review and Meta-analysis and Guideline Recommendation. JAMA network open 2021. link 2 Corwin DJ, Master CL, Grady MF, Zonfrillo MR. The Economic Burden of Pediatric Postconcussive Syndrome. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine 2020. link 3 Sainani KL. The Problem with "Magnitude-based Inference". Medicine and science in sports and exercise 2018. link 4 Maroon JC, Lepere DB, Blaylock RL, Bost JW. Postconcussion syndrome: a review of pathophysiology and potential nonpharmacological approaches to treatment. The Physician and sportsmedicine 2012. link

    Original source

    1. [1]
      Nonpharmacological Treatment of Persistent Postconcussion Symptoms in Adults: A Systematic Review and Meta-analysis and Guideline Recommendation.Rytter HM, Graff HJ, Henriksen HK, Aaen N, Hartvigsen J, Hoegh M et al. JAMA network open (2021)
    2. [2]
      The Economic Burden of Pediatric Postconcussive Syndrome.Corwin DJ, Master CL, Grady MF, Zonfrillo MR Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine (2020)
    3. [3]
      The Problem with "Magnitude-based Inference".Sainani KL Medicine and science in sports and exercise (2018)
    4. [4]
      Postconcussion syndrome: a review of pathophysiology and potential nonpharmacological approaches to treatment.Maroon JC, Lepere DB, Blaylock RL, Bost JW The Physician and sportsmedicine (2012)

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