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Hematology27 papers

Retroperitoneal infection

Last edited: 4/15/2026

Overview

Retroperitoneal infections encompass a range of inflammatory conditions affecting the retroperitoneal space, often requiring precise diagnostic approaches to differentiate from other masses like lymphadenopathy or adrenal lesions. 1

Diagnosis

  • CT Scan: Essential for evaluating retroperitoneal masses and lymphadenopathy; guides biopsy procedures. 1
  • Transretroperitoneal Core Biopsy: Preferred for diagnosing primary retroperitoneal masses under CT guidance. 1
  • Open Biopsy: Recommended for undiagnosed lymphadenopathy. 1
  • Colour Doppler Ultrasound: Useful for distinguishing retroperitoneal varices from masses, avoiding unnecessary invasive procedures. 2
  • Management

  • Biopsy and Resection: Large or enlarging nonfunctional primary adrenal masses should be resected without prior biopsy. 1
  • Avoid Unnecessary Biopsies: Particularly in suspected retroperitoneal varices to prevent complications; colour Doppler can confirm diagnosis safely. 2
  • Special Populations

  • No Specific Guidance Provided: The abstracts do not cover management specifics for pregnancy, pediatrics, elderly, or comorbidities related to retroperitoneal infections.
  • Key Recommendations

  • Utilize CT scan-guided transretroperitoneal core biopsy for diagnosing primary retroperitoneal masses (Evidence: Moderate) 1
  • Employ colour Doppler ultrasound to safely differentiate retroperitoneal varices from masses, avoiding risky biopsies (Evidence: Weak) 2
  • Resect large or enlarging nonfunctional primary adrenal masses without prior biopsy (Evidence: Expert opinion) 1
  • References

    1 Storm FK, Mahvi DM, Hafez GR. Retroperitoneal masses, adenopathy, and adrenal glands. Surgical oncology clinics of North America 1995. link 2 Kedar RP, Cosgrove DO. Case report: retroperitoneal varices mimicking a mass: diagnosis on colour Doppler. The British journal of radiology 1994. link

    Original source

    1. [1]
      Retroperitoneal masses, adenopathy, and adrenal glands.Storm FK, Mahvi DM, Hafez GR Surgical oncology clinics of North America (1995)
    2. [2]
      Case report: retroperitoneal varices mimicking a mass: diagnosis on colour Doppler.Kedar RP, Cosgrove DO The British journal of radiology (1994)

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