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Allergy & Immunology19 papers

Infection caused by Vibrio

Last edited: 4/15/2026

Overview

Vibriosis encompasses infections caused by marine bacteria, primarily Vibrio species, including Vibrio vulnificus, which can lead to severe systemic infections and cholera 1.

Diagnosis

  • Suspect vibriosis in patients with chronic underlying diseases, recent raw seafood ingestion, and characteristic skin lesions 2.
  • Clinical presentation may include diffuse pulmonary infiltrates in cases of septicemia 2.
  • Laboratory tests should include blood cultures to identify Vibrio species 2.
  • Imaging studies like chest X-rays may reveal pulmonary infiltrates in severe cases 2.
  • Management

  • First-line treatment typically involves empiric broad-spectrum antibiotics such as third-generation cephalosporins or fluoroquinolones pending culture results 2.
  • Specific antibiotic choices may need adjustment based on susceptibility testing results 2.
  • Supportive care is crucial, including fluid resuscitation and management of organ dysfunction 2.
  • Monitoring for and addressing complications like sepsis and respiratory failure is essential 2.
  • Special Populations

  • No specific details provided regarding management in pregnancy, pediatrics, elderly, or patients with comorbidities 12.
  • Key Recommendations

  • Suspect vibriosis in patients with predisposing conditions, recent raw seafood exposure, and characteristic clinical features (Evidence: Expert opinion 2).
  • Initiate empiric broad-spectrum antibiotic therapy pending culture results for suspected Vibrio septicemia (Evidence: Expert opinion 2).
  • Closely monitor for and manage complications such as pulmonary infiltrates and sepsis in affected patients (Evidence: Expert opinion 2).
  • References

    1 Marques PH, Rodrigues TCV, Santos EH, Bleicher L, Aburjaile FF, Martins FS et al.. Design of a multi-epitope vaccine (vme-VAC/MST-1) against cholera and vibriosis based on reverse vaccinology and immunoinformatics approaches. Journal of biomolecular structure & dynamics 2025. link 2 Cunningham LW, Promisloff RA, Cichelli AV. Pulmonary infiltrates associated with Vibrio vulnificus septicemia. The Journal of the American Osteopathic Association 1991. link

    Original source

    1. [1]
      Design of a multi-epitope vaccine (vme-VAC/MST-1) against cholera and vibriosis based on reverse vaccinology and immunoinformatics approaches.Marques PH, Rodrigues TCV, Santos EH, Bleicher L, Aburjaile FF, Martins FS et al. Journal of biomolecular structure & dynamics (2025)
    2. [2]
      Pulmonary infiltrates associated with Vibrio vulnificus septicemia.Cunningham LW, Promisloff RA, Cichelli AV The Journal of the American Osteopathic Association (1991)

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