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Cardiology146 papers

Disease caused by Gram-negative bacillus

Last edited: 4/15/2026

Overview

Infections caused by Gram-negative bacilli encompass a broad spectrum of diseases, often presenting with systemic symptoms and requiring prompt antimicrobial therapy. Aeromonas hydrophila, a notable pathogen, can lead to severe localized infections following trauma such as snake bites 1.

Diagnosis

  • Clinical presentation includes fulminant local infection symptoms (e.g., severe swelling, redness, pain) 1.
  • Microbiological confirmation through culture and sensitivity testing of infected tissue samples 1.
  • Imaging (e.g., X-ray, ultrasound) may be necessary to assess extent of tissue damage 1.

    • Management

  • First-line treatment: Intravenous antimicrobial therapy targeting Aeromonas hydrophila, such as fluoroquinolones or third-generation cephalosporins 1.
  • Adjunctive measures: Surgical debridement or intervention to manage tissue necrosis or abscess formation 1.
  • Supportive care including fluid resuscitation and pain management 1.

    • Special Populations

  • Pediatrics: Fulminant infections can occur in children, necessitating early aggressive intervention 1.
  • Comorbidities: No specific comorbidities highlighted in the provided abstracts 1.

    • Key Recommendations

  • Initiate prompt intravenous antimicrobial therapy targeting Aeromonas species following suspected infection 1 (Evidence: Weak).
  • Consider surgical intervention for severe tissue damage or abscess formation 1 (Evidence: Weak).
  • Provide supportive care including fluid management and pain relief alongside antimicrobial treatment 1 (Evidence: Weak).

    • References

    1 Thisyakorn U, Thisyakorn C. Aeromonas infection following a snake bite: a case report. The Southeast Asian journal of tropical medicine and public health 1988. link

    Original source

    1. [1]
      Aeromonas infection following a snake bite: a case report. — Thisyakorn U, Thisyakorn C The Southeast Asian journal of tropical medicine and public health (1988)
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