Overview
Verrucous carcinoma (VC) is a rare, slow-growing mucocutaneous malignancy with a low reported rate of metastasis 1. It is characterized by relentless growth 1.Diagnosis
No specific diagnostic criteria, recommended tests, or grading systems are mentioned in the provided abstracts.Management
Surgical management is the first-line therapy for verrucous carcinoma 1.
Wide local excision is commonly utilized, with reported margins ranging from 0.5 to 3.0 cm 1.
Mohs Micrographic Surgery (MMS) is an alternative, particularly for recurrent tumors 1.
Recurrence rates after wide local excision are highly variable (4.6-75.0%), while the recurrence rate after MMS is reported as 12.9% 1.
Tissue-sparing therapies are desirable due to the sensitive locations often involved 1.
Randomized controlled trials are needed to develop evidence-based guidelines 1.Special Populations
No information is available on special populations.Key Recommendations
Surgery is the treatment of choice for verrucous carcinoma, either via Mohs Micrographic Surgery or wide local excision 1. (Evidence: Moderate)
Wide local excision is a commonly utilized surgical approach 1. (Evidence: Moderate)
Mohs Micrographic Surgery may be used, especially for recurrent tumors 1. (Evidence: Moderate)References
1 Fawaz B, Vieira C, Decker A, Lawrence N. Surgical treatment of verrucous carcinoma: a review. The Journal of dermatological treatment 2022. link