Overview
Spirochetal infections, such as syphilis, can be transmitted from a pregnant individual to their fetus, leading to congenital syphilis. Untreated congenital syphilis can result in severe adverse outcomes for the infant, including premature birth, low birth weight, stillbirth, neonatal death, and significant developmental abnormalities 1.Diagnosis
Screening for syphilis infection in pregnant individuals is recommended 1.Management
(No information provided in abstracts)Special Populations
Pregnancy:
* Universal screening for syphilis infection during pregnancy is recommended 1.
* If not screened early in pregnancy, screening should occur at the first available opportunity 1.Key Recommendations
Screening for syphilis infection in pregnancy has a substantial net benefit 1. (Evidence: Strong)
The US Preventive Services Task Force recommends early, universal screening for syphilis infection during pregnancy 1. (Evidence: Strong)
If an individual is not screened early in pregnancy, screening should occur at the first available opportunity 1. (Evidence: Strong)References
1 Silverstein M, Wong JB, Davis EM, Chelmow D, Coker TR, Fernandez A et al.. Screening for Syphilis Infection During Pregnancy: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA 2025. link