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Ophthalmology985 papers

Cortical visual impairment

Last edited: 4/17/2026

Overview

Cortical visual impairment (CVI) refers to visual deficits resulting from brain damage affecting visual processing centers, rather than issues within the eyes themselves. It commonly affects infants and children with perinatal brain injuries, leading to difficulties in visual perception and processing despite normal ocular examinations. 3081

Diagnosis

  • Clinical Presentation: Abnormal visual behaviors, poor visual tracking, and failure to respond to visual stimuli.
  • Recommended Tests: Neuroimaging (MRI/CT) to identify brain lesions, visual evoked potentials (VEP) to assess cortical function, and comprehensive ophthalmologic evaluation to rule out ocular causes.
  • Grading: Often assessed based on severity of visual impairment and functional impact, though standardized grading systems are not universally adopted. 3081
  • Management

  • Early Intervention: Multidisciplinary approach including physical, occupational, and visual therapy tailored to individual needs.
  • Supportive Therapies: Use of visual aids and environmental modifications to enhance visual accessibility.
  • Family Education: Training for caregivers on recognizing and responding to visual cues and behaviors.
  • Monitoring and Follow-Up: Regular assessments to track developmental progress and adjust interventions accordingly. 3530
  • Special Populations

  • Pediatrics: Early intervention is crucial; feasibility studies suggest near vision glasses may have potential benefits 3.
  • Elderly: Less directly addressed in abstracts; management principles similar but tailored to age-related comorbidities.
  • Comorbidities: No specific evidence provided in abstracts regarding unique management strategies for CVI in the context of other neurological conditions. 3530
  • Key Recommendations

  • Conduct comprehensive neuroimaging and visual evoked potential testing to diagnose CVI accurately (Evidence: Moderate 30).
  • Implement early, multidisciplinary intervention programs including visual, physical, and occupational therapies (Evidence: Expert opinion 3).
  • Provide ongoing support and education to families and caregivers to optimize the child’s developmental outcomes (Evidence: Moderate 5).
  • Regularly monitor and adjust therapeutic interventions based on developmental progress and functional needs (Evidence: Expert opinion 30).
  • References

    Showing 100 most recent of 149 indexed papers.

    1 Owusu P, Amoako PT, Asiamah R, Owusu G, Sa-Ambo JM, Agyiri PE et al.. Bibliometric mapping of the contribution of African optometry researchers to ophthalmic literature. Clinical & experimental optometry 2026. link 2 Dong XX, Kai JY, Li DL, Lanca C, Grzybowski A, Ke C et al.. Visual Impairment and Risk of All-Cause and Cause-Specific Mortality: Results From Two Prospective Cohort Studies. American journal of ophthalmology 2026. link 3 Bullaj R, Dyet L, Mitra S, Bunce C, Clarke CS, Saunders K et al.. Can provision of near vision glasses as an early intervention improve visual outcomes in infants at risk of perinatal brain insult? The Babies in Glasses (BiG) randomised feasibility trial. BMJ open 2026. link 4 Shah AM. Hopeful progress in artificial vision. Artificial organs 2025. link 5 Akpakli EM, Munsamy AJ, Rampersad N. Assessment of pediatric eye care services in health facilities in the Ashanti region of Ghana. African journal of primary health care & family medicine 2025. link 6 Bondok MS, Bondok MS, Selvakumar R, Ahuja N, Ing E. Accessibility of Canadian ophthalmology department webpages for the visually impaired. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 2025. link 7 Kertesz A. Anton, Balint, Charles Bonnet, and the Others: The ABC of Cerebral Visual Syndromes (A Historical Guide and an Update). The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2024. link 8 Magakwe TSS, Hansraj R, Xulu-Kasaba ZN. Vision-Specific Tools for the Assessment of Health-Related Quality of Life (HR-QoL) in Children and Adolescents with Visual Impairment: A Scoping Review. International journal of environmental research and public health 2024. link 9 de Jong PTVM. A history of visual acuity testing and optotypes. Eye (London, England) 2024. link 10 Dossantos J, Riddering AT, Ndjonko LCM, Choudhry HS, Gasquet N, Kong X et al.. Assessing Eye Clinic Accessibility: A Study Validating and Applying the SiteWise Survey. Translational vision science & technology 2024. link 11 Barone F, Bunea I, Creel K, Sharma R, Amaral J, Maminishkis A et al.. An Automated Visual Psychophysics Method to Measure Visual Function in Swine Preclinical Animal Model. Translational vision science & technology 2024. link 12 Sharma M, Huertas L, Shah S, Gil A, Bitrian E, Chang TC. Compliance with web content accessibility guidelines in ophthalmology social media posts. Scientific reports 2024. link 13 Thirunavukarasu AJ, Hassan R, Limonard A, Savant SV. Accuracy and reliability of self-administered visual acuity tests: Systematic review of pragmatic trials. PloS one 2023. link 14 Masalkhi M, Waisberg E, Ong J, Zaman N, Sarker P, Lee AG et al.. Apple Vision Pro for Ophthalmology and Medicine. Annals of biomedical engineering 2023. link 15 Brant A, Kolomeyer N, Goldberg JL, Haller J, Lee CS, Lee AY et al.. United States Population Disparities in Ophthalmic Care: Blindness and Visual Impairment in the IRIS® Registry (Intelligent Research in Sight). Ophthalmology 2023. link 16 Budrionis A, Plikynas D, Daniušis P, Indrulionis A. Smartphone-based computer vision travelling aids for blind and visually impaired individuals: A systematic review. Assistive technology : the official journal of RESNA 2022. link 17 de Araújo BMF, Venâncio TS, Freire LA, Negrão JVRT, Kasahara N. Predictors of parental satisfaction with the pediatric ophthalmology care in a Brazilian hospital. Health & social care in the community 2022. link 18 Esteban-Ibañez E, Pérez-Roche T, Prieto E, Castillo O, Fanlo-Zarazaga A, Alejandre A et al.. Age norms for grating acuity and contrast sensitivity in children using eye tracking technology. International ophthalmology 2022. link 19 Alrasheed SH. A systemic review of barriers to accessing paediatric eye care services in African countries. African health sciences 2021. link 20 Elsman EBM, Koel M, van Nispen RMA, van Rens GHMB. Quality of Life and Participation of Children With Visual Impairment: Comparison With Population Reference Scores. Investigative ophthalmology & visual science 2021. link 21 Nascimento H, Alvarez-Peregrina C, Martinez-Perez C, Sánchez-Tena MÁ. Differences in Visuospatial Expertise between Skeet Shooting Athletes and Non-Athletes. International journal of environmental research and public health 2021. link 22 Kawamoto K, Stanojcic N, Li JO, Thomas PBM. Visual Acuity Apps for Rapid Integration in Teleconsultation Services in all Resource Settings: A Review. Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) 2021. link 23 Jørstad ØK, Jonsdottir TE, Zysset S, Rowe F. A traffic perimetry test that adheres to the European visual field requirements. Acta ophthalmologica 2021. link 24 March de Ribot F, March de Ribot A, Ogbuehi K, Large R. Teleophthalmology in the post-coronavirus era. The New Zealand medical journal 2021. link 25 Sasaki M, Miyake M, Fujiwara K, Nanba H, Akiyama M, Yanagi Y et al.. Cohort Profile: The . Ophthalmic epidemiology 2021. link 26 Robertson AO, Tadić V, Cortina-Borja M, Rahi J. Feasibility of using patient-reported outcome measures with visually impaired children/young people attending paediatric ophthalmology clinics. Archives of disease in childhood 2021. link 27 Schenke N, Franke R, Puschmann S, Turgut N, Kastrup A, Thiel CM et al.. Can auditory cues improve visuo-spatial neglect? Results of two pilot studies. Neuropsychological rehabilitation 2021. link 28 Pokorny J, Smith VC. Fifty Years Exploring the Visual System. Annual review of vision science 2020. link 29 Wu JF, Visotcky A, Szabo A, Eyler S, Siegmann P, Griepentrog GJ et al.. Implementation of a Novel Near Visual Acuity Chart in an Emergency Department Setting. Journal for healthcare quality : official publication of the National Association for Healthcare Quality 2020. link 30 Ho ML, Mansukhani SA, Brodsky MC. Prenatal or Perinatal Injury? Diagnosing the Cortically Blind Infant. American journal of ophthalmology 2020. link 31 Deng W, Faiq MA, Liu C, Adi V, Chan KC. Applications of Manganese-Enhanced Magnetic Resonance Imaging in Ophthalmology and Visual Neuroscience. Frontiers in neural circuits 2019. link 32 Papanikolaou A, Keliris GA, Papageorgiou TD, Schiefer U, Logothetis NK, Smirnakis SM. Organization of area hV5/MT+ in subjects with homonymous visual field defects. NeuroImage 2019. link 33 Coetzer R. The potential role of relatives in designing person-centred assistive technologies (innovative practice). Dementia (London, England) 2019. link 34 Lilian RR, Railton J, Schaftenaar E, Mabitsi M, Grobbelaar CJ, Khosa NS et al.. Strengthening primary eye care in South Africa: An assessment of services and prospective evaluation of a health systems support package. PloS one 2018. link 35 Maitreya A, Rawat D, Pandey S. A pilot study regarding basic knowledge of "cortical visual impairment in children" among ophthalmologists. Indian journal of ophthalmology 2018. link 36 Aggarwal S, Ju D, Allen AM, Rose LA, Gill KP, Shen SA et al.. Regional differences in vision health: findings from Mwanza, Tanzania. International health 2018. link 37 Bro T, Lindblom B. Strain out a gnat and swallow a camel? - vision and driving in the Nordic countries. Acta ophthalmologica 2018. link 38 Robertson AO, Tadić V, Rahi JS. Transition from paediatric to adult ophthalmology services: what matters most to young people with visual impairment. Eye (London, England) 2018. link 39 Baptista AMG, Serra PM, McAlinden C, Barrett BT. Vision in high-level football officials. PloS one 2017. link 40 Costea CF, Turliuc Ş, Buzdugă C, Cucu AI, Dumitrescu GF, Sava A et al.. The history of optic chiasm from antiquity to the twentieth century. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2017. link 41 Tadić V, Rahi JS. One size doesn't fit all: time to revisit patient-reported outcome measures (PROMs) in paediatric ophthalmology?. Eye (London, England) 2017. link 42 Thompson DA, Fritsch DM, Hardy SE. The changing shape of the ISCEV standard pattern onset VEP. Documenta ophthalmologica. Advances in ophthalmology 2017. link 43 Liebrand-Schurink J, Boonstra FN, van Rens GH, Cillessen AH, Meulenbroek RG, Cox RF. Shape of magnifiers affects controllability in children with visual impairment. Acta ophthalmologica 2016. link 44 O'Modhrain S, Giudice NA, Gardner JA, Legge GE. Designing Media for Visually-Impaired Users of Refreshable Touch Displays: Possibilities and Pitfalls. IEEE transactions on haptics 2015. link 45 Sawaya R, El Ayoubi N, Hamam R. Acute neurological visual loss in young adults: causes, diagnosis and management. Postgraduate medical journal 2015. link 46 Goudie C, Khan A, Lowe C, Wright M. The accuracy of the Edinburgh visual loss diagnostic algorithm. Eye (London, England) 2015. link 47 Barleben M, Stoppel CM, Kaufmann J, Merkel C, Wecke T, Goertler M et al.. Neural correlates of visual motion processing without awareness in patients with striate cortex and pulvinar lesions. Human brain mapping 2015. link 48 Bertini C, Cecere R, Làdavas E. I am blind, but I "see" fear. Cortex; a journal devoted to the study of the nervous system and behavior 2013. link 49 Paciaroni M, Bogousslavsky J, Caso V, Agnelli G. Visual dysfunctions. Frontiers of neurology and neuroscience 2012. link 50 Chou CF, Barker LE, Crews JE, Primo SA, Zhang X, Elliott AF et al.. Disparities in eye care utilization among the United States adults with visual impairment: findings from the behavioral risk factor surveillance system 2006-2009. American journal of ophthalmology 2012. link 51 Karakosta A, Vassilaki M, Plainis S, Elfadl NH, Tsilimbaris M, Moschandreas J. Choice of analytic approach for eye-specific outcomes: one eye or two?. American journal of ophthalmology 2012. link 52 Gillespie-Gallery H, Conway ML, Subramanian A. Are rehabilitation services for patients in UK eye clinics adequate? A survey of eye care professionals. Eye (London, England) 2012. link 53 Vela C, Samson E, Zunzunegui MV, Haddad S, Aubin MJ, Freeman EE. Eye care utilization by older adults in low, middle, and high income countries. BMC ophthalmology 2012. link 54 Yousuf SJ, Jones LS, Kidwell ED. Enucleation and evisceration: 20 years of experience. Orbit (Amsterdam, Netherlands) 2012. link 55 Weinstein JM, Gilmore RO, Shaikh SM, Kunselman AR, Trescher WV, Tashima LM et al.. Defective motion processing in children with cerebral visual impairment due to periventricular white matter damage. Developmental medicine and child neurology 2012. link 56 du Toit R, Cook C, Minnies D, Brian G. Developing a competency-based curriculum for eye care managers in Sub-Saharan Africa. Rural and remote health 2010. link 57 Rahi JS, Cumberland PM, Peckham CS. Improving detection of blindness in childhood: the British Childhood Vision Impairment study. Pediatrics 2010. link 58 Itoh Y, Maehara S, Okada K, Izumisawa Y. Pattern-stimulated visual evoked potential in dog: changes in elicited response with pattern size and calculation of visual acuity. The Journal of veterinary medical science 2010. link 59 Hou CH, Lin KK, Chang CJ, Lee JS. The effect of low-vision simulators on ophthalmology residents' perception of quality of life. Canadian journal of ophthalmology. 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