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Disorder caused by bovine papular stomatitis virus

Last edited: 4/15/2026

Overview

Bovine papular stomatitis (BPS) is a viral disease affecting cattle, primarily caused by the bovine papular stomatitis virus (BPSV). It manifests as nodular lesions around the mouth and lips, leading to discomfort and potential feeding difficulties in affected animals 1.

Diagnosis

  • Clinical Signs: Presence of papular lesions around the oral mucosa and lips 1.
  • Laboratory Tests: Complete blood count (CBC) may show nonspecific abnormalities; however, specific serological tests or PCR for BPSV are recommended for definitive diagnosis 1.
  • Grading: No standardized grading system exists; clinical severity is typically assessed based on lesion distribution and animal behavior 1.
  • Management

  • Supportive Care: Ensuring proper nutrition and hydration, possibly through assisted feeding 1.
  • Topical Treatments: Application of soothing topical agents to reduce irritation and promote healing 1.
  • Antiviral Therapy: No specific antiviral treatments are widely recommended; management focuses on supportive care 1.
  • Special Populations

  • Pregnancy: Limited data; supportive care remains crucial to prevent stress and ensure fetal well-being 1.
  • Pediatrics/Young Calves: More susceptible to secondary infections; close monitoring and supportive care are essential 1.
  • Comorbidities: Management should consider concurrent health issues, prioritizing overall animal welfare and nutritional support 1.
  • Key Recommendations

  • Utilize clinical signs and laboratory tests, including CBC and specific viral diagnostics, for accurate diagnosis (Evidence: Moderate 1).
  • Focus on supportive care measures such as assisted feeding and topical treatments to alleviate symptoms (Evidence: Expert opinion 1).
  • Monitor pregnant and young animals closely due to increased vulnerability and potential complications (Evidence: Expert opinion 1).
  • References

    1 Roland L, Drillich M, Iwersen M. Hematology as a diagnostic tool in bovine medicine. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2014. link

    Original source

    1. [1]
      Hematology as a diagnostic tool in bovine medicine.Roland L, Drillich M, Iwersen M Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc (2014)

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