Overview
Cerebral degeneration encompasses various pathological processes affecting brain structure and function, often exacerbated by aging and contributing to cerebrovascular diseases such as stroke, cognitive decline, and white matter lesions. These conditions are influenced by factors including inflammation, metabolic disturbances, vascular stiffness, and genetic predispositions. 217213050Diagnosis
Management
Special Populations
Key Recommendations
References
Showing 100 most recent of 2205 indexed papers.
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Amplified microglial dysfunction and brain lesions in mouse models for comorbidity of chronic stress and cerebral hypoperfusion. Brain, behavior, and immunity 2026. link 21 Lin CC, Li CI, Liu CS, Lin CH, Yang SY, Li TC. Glucose-Related Genetic Risk Score and Its Association With Cerebrovascular Abnormality, White-Matter Hyperintensity Volume, and Brain Microstructure Markers. Geriatrics & gerontology international 2026. link 22 Farhani N, Costa YS, Rozik M, Spruyt K, Walters AS, Boulos MI. Restless legs syndrome and periodic limb movements of sleep - the relationship with stroke and other cerebrovascular disease. Nature reviews. Neurology 2026. link 23 Shen CL, Huang LY, Chen JK, Tsai ST, Wu YF. Flow Cytometric Profiling Reveals Platelet Dysfunction and Impaired Immune Communication in Acute and Chronic Cerebrovascular Disease. Journal of clinical laboratory analysis 2026. link 24 Ramdani N, Kyselyova AA, MacMillan N, Ngo NT, Schmiech J, Wagner M et al.. Development and Validation of a Novel Stenosis Model for Percutaneous Transluminal Angioplasty Training of the Internal Carotid Artery. Clinical neuroradiology 2026. link 25 Funayama M, Sato K, Nakagawa Y. Thermoregulatory dysfunction in the chronic phase of cerebrovascular disease: Hypothalamus damage and behavior control deficits. Neuropsychology 2026. link 26 Grin EA, Sharashidze V, Chung C, Baranoski JF, Rutledge C, Riina HA et al.. Early experience with the Drivewire 24: a newly FDA-approved steerable microwire. Journal of neurointerventional surgery 2026. link 27 Hassan IN, Yaqub S, Ibrahim M, Abuassa N, Ibrahim M, Ahmed S et al.. National Trends in Cerebrovascular Disease-Related Mortality among Adults With Obesity in the United States, 1999-2020. Brain and behavior 2026. link 28 Adapa AR, Siddiqui FM, Pandey AS. Device use trends in neuroendovascular procedures in the United States from 2015 to 2020. 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Quality evaluation of health science popularization short videos related to cerebrovascular diseases on popular short video platforms in China: cross-sectional study. Frontiers in public health 2026. link 33 Kim MH, Gil JY, Min KH, Kim JH, Park JH, Park S et al.. Association between SGLT2 inhibitors and recurrence of cerebrovascular events in patients with type 2 diabetes: A population-based cohort study. Diabetes & vascular disease research 2026. link 34 Ururahy RDR, Justo AFO, Leite REP, Ribeiro Paes V, Conforto AB, Grinberg LT et al.. Microvascular and Macrovascular Cerebral Disease Profiles and Their Association With Cognitive Abilities: A Cross-Sectional Clinical Pathological Study. Stroke 2026. link 35 Ayadi N, Riegler C, Nawabi J, Radbruch H, Charidimou A, Nolte CH. Relationship Between Hematoma Location and Underlying Small Vessel Disease in Cerebellar Intracerebral Hemorrhage. 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Temporal trends and disparities in atherosclerosis-associated cerebrovascular disease mortality in the United States, 1999-2020. Current problems in cardiology 2025. link 45 McGuire LS, Abou-Mrad T, Atwal G, Amin-Hanjani S, Charbel FT. Does disease etiology matter in long-term patency in extracranial-intracranial bypass?. Journal of neurosurgery 2025. link 46 Wang S, Pan H, Yuan J, Zhang W. Effects of CICARE model combined with traditional Chinese medicine encapsulation on muscle strength and depression levels in hemiplegic patients with sequelae of cerebrovascular disease. The International journal of neuroscience 2025. link 47 Li X, Li Y, Wang T, Sun X, Lu G, Xu X et al.. Determining the Optimal Age for Extracranial-Intracranial Bypass Surgery: A Post Hoc Analysis of the CMOSS Randomized Trial. Stroke 2025. link 48 Dong HW, Ghahremani JS, Singh Rana SS, Safran BA, Lau DL, Brewer MB. Bow Hunter Phenomenon From Advanced Cerebrovascular Disease Treated With Subclavian Artery Stenting and Carotid Endarterectomy. Vascular and endovascular surgery 2025. link 49 Bijnen M, Sridhar S, Keller A, Greter M. Brain macrophages in vascular health and dysfunction. Trends in immunology 2025. link 50 Moghaddasi H, Rahimi F, Seddighi AS, Akbarpour L, Roshanpoor A. A decision support system to increase the compliance of diagnostic imaging examinations with imaging guidelines: focused on cerebrovascular diseases. Diagnosis (Berlin, Germany) 2025. link 51 Zvolanek KM, Moore JE, Jarvis K, Moum SJ, Bright MG. Macrovascular blood flow and microvascular cerebrovascular reactivity are regionally coupled in adolescence. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2025. link 52 Golub D, McBriar JD, Mehta SH, Shah HA, Turpin J, White TG et al.. The impact of cerebrovascular steno-occlusive disease subtype on surgical and clinical outcomes after direct STA-MCA bypass surgery. Journal of neurosurgery 2025. link 53 Qin Q, Feng M, Zhang K, Mo Z, Liu Y, Ma Y et al.. Basigin in cerebrovascular diseases: Roles, mechanisms, and therapeutic target potential. European journal of pharmacology 2025. link 54 Albertson AJ, Winkler EA, Yang AC, Buckwalter MS, Dingman AL, Fan H et al.. Single-Cell Analysis in Cerebrovascular Research: Primed for Breakthroughs and Clinical Impact. Stroke 2025. link 55 Uchiyama S, Hoshino T, Minematsu K, Meledje ML, Charles H, Albers GW et al.. Risk of major vascular events in patients without traditional risk factors after transient ischemic attack or minor ischemic stroke: An international prospective cohort. European stroke journal 2025. link 56 Chen Y, Chen C, Li X, Xiao R. SIAM: Spatial and Intensity Awareness Module for cerebrovascular segmentation. 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