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Fascicular ventricular tachycardia

Last edited: 4/23/2026

Overview

Fascicular ventricular tachycardia (FVT) is a specific type of ventricular tachycardia originating from the left ventricular Purkinje network, typically characterized by a narrow QRS complex and multiform morphology on the ECG 1.

Diagnosis

  • ECG Features: Narrow QRS complex, often multiform morphology 1.
  • Electrolyte Imbalance Consideration: Evaluate for digoxin toxicity, as it can precipitate FVT 1.
  • Electrophysiology Studies: May be necessary for definitive diagnosis and mapping of the tachycardia origin 1.
  • Management

  • First-Line Treatment: Administration of Fab fragments for digoxin toxicity can slow and morphologically standardize the tachycardia 1.
  • Adjunctive Treatments: Consider antiarrhythmic drugs like beta-blockers or class Ic agents (e.g., flecainide) if Fab fragments are ineffective 1.
  • Cardioversion: Indicated for hemodynamically unstable patients 1.
  • Special Populations

  • Digoxin Toxicity: Special attention to Fab fragment therapy in cases where digoxin toxicity is suspected 1.
  • Key Recommendations

  • Administer Fab fragments for suspected digoxin-induced fascicular ventricular tachycardia to slow and standardize the tachycardia morphology (Evidence: Moderate 1).
  • Consider cardioversion for patients with hemodynamic instability due to FVT (Evidence: Expert opinion 1).
  • Evaluate and manage electrolyte imbalances, particularly digoxin levels, in patients presenting with FVT (Evidence: Moderate 1).
  • References

    1 Wieland JM, Marchlinski FE. Electrocardiographic response of digoxin-toxic fascicular tachycardia to Fab fragments: implications for tachycardia mechanism. Pacing and clinical electrophysiology : PACE 1986. link

    Original source

    1. [1]

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