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Ophthalmology6 papers

Chalicosis

Last edited: 4/15/2026

Overview

Chalazion is a common inflammatory lesion of the eyelid caused by the retention of secretions from meibomian glands, leading to painless swelling of the eyelid 1.

Diagnosis

  • Clinical presentation: painless, localized swelling of the eyelid 1.
  • No specific diagnostic tests; clinical evaluation is typically sufficient 1.
  • Management

  • First-line treatments: Warm compresses applied several times daily 12.
  • Adjunctive treatments: Intralesional corticosteroid injections (dose specifics not provided) 2.
  • Surgical intervention: Tarsus trephination for persistent cases with minimal recurrences and complications 3.
  • Special Populations

  • Pediatrics: Vitamin A deficiency may be a potential risk factor for chalazion development in children 1.
  • Comorbidities: No specific management adjustments noted for elderly or comorbid conditions in the provided abstracts.
  • Key Recommendations

  • Evaluate vitamin A levels in pediatric patients with recurrent chalazions to assess deficiency as a contributing factor (Evidence: Moderate) 1.
  • Warm compresses should be the initial treatment approach for managing chalazia 2.
  • Consider intralesional corticosteroid injections for chalazia that do not respond to conservative management 2.
  • For refractory cases, surgical intervention such as tarsus trephination can be effective with low recurrence rates 3 (Evidence: Weak).
  • References

    1 Cheng H, Lv X, Yao J, Chen Z. Clinical Report: Correlation of Serum Vitamins and Chalazion. Optometry and vision science : official publication of the American Academy of Optometry 2022. link 2 Smythe D, Hurwitz JJ, Tayfour F. The management of chalazion: a survey of Ontario ophthalmologists. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 1990. link 3 Leachman JW, Boynton JR, Levin DB. Chalazion management by tarsus trephination. Ophthalmic surgery 1978. link

    Original source

    1. [1]
      Clinical Report: Correlation of Serum Vitamins and Chalazion.Cheng H, Lv X, Yao J, Chen Z Optometry and vision science : official publication of the American Academy of Optometry (2022)
    2. [2]
      The management of chalazion: a survey of Ontario ophthalmologists.Smythe D, Hurwitz JJ, Tayfour F Canadian journal of ophthalmology. Journal canadien d'ophtalmologie (1990)
    3. [3]
      Chalazion management by tarsus trephination.Leachman JW, Boynton JR, Levin DB Ophthalmic surgery (1978)

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