Overview
Acommissural unicuspid aortic valve is a congenital bicuspid aortic valve variant characterized by the absence of a commissure, resulting in a single raphe 1. This anatomical variation can lead to aortic stenosis or regurgitation 1.Diagnosis
Diagnosis is typically made via echocardiography, which can identify the unicuspid morphology and assess valve function 1.
Aortic valve stenosis and regurgitation are the primary hemodynamic consequences 1.Management
Transcatheter aortic valve implantation (TAVI) with the ACURATE neo valve has been studied for aortic valve replacement 1.
In a meta-analysis of TAVI with the ACURATE neo valve, device success was achieved in 94.5% of patients 1.
Thirty-day outcomes for TAVI with the ACURATE neo valve included all-cause mortality of 1.8%, stroke in 1.9%, myocardial infarction in 0.5%, new permanent pacemaker implantation in 7.7%, major bleeding in 5.0%, major vascular complications in 5.6%, acute kidney injury (stage ≥2) in 2.5%, and moderate or severe paravalvular leak in 4.3% 1.Key Recommendations
Transcatheter aortic valve implantation with the ACURATE neo valve is a viable option for aortic valve replacement, with high rates of device success 1. (Evidence: Moderate)
Clinicians should be aware of the potential 30-day complications associated with TAVI, including mortality, stroke, myocardial infarction, need for pacemaker, bleeding, vascular complications, acute kidney injury, and paravalvular leak 1. (Evidence: Moderate)References
1 Koliastasis L, Doundoulakis I, Kokkinidis DG, Milkas A, Kostopoulos G, Drakopoulou M et al.. Study Level Meta-Analysis of Transcatheter Aortic Valve Implantation With the ACURATE neo Self-Expanding Transcatheter Heart Valve. Cardiology in review 2023. link