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Ulcerative stomatitis

Last edited: 4/10/2026

Overview

Ulcerative stomatitis, commonly referred to as mucositis, is a significant toxicity of cancer therapy that can lead to numerous systemic sequelae 1. It is characterized by inflammation and ulceration of the mucous membranes of the oral cavity 1.

Diagnosis

  • Grading of mucositis is performed using established criteria 1.
  • Management

  • Management strategies are evidence-based and setting-specific for patients undergoing cancer therapy 1.
  • Guidelines cover various interventions for mucositis 1.
  • Key Recommendations

  • Guidelines are developed based on the level of evidence, with possible determinations of recommendation, suggestion, or no guideline possible 1.
  • The MASCC/ISOO Clinical Practice Guidelines provide a clinical setting-specific, evidence-based tool for managing mucositis in cancer patients 1.
  • Thirteen new guidelines were developed for or against the use of various interventions in specific treatment settings 1.
  • Eleven previous guidelines were confirmed after a review of new evidence 1.
  • Thirteen previously established guidelines were carried over due to a lack of new evidence 1.
  • References

    1 Elad S, Cheng KKF, Lalla RV, Yarom N, Hong C, Logan RM et al.. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer 2020. link

    Original source

    1. [1]
      MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy.Elad S, Cheng KKF, Lalla RV, Yarom N, Hong C, Logan RM et al. Cancer (2020)

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