Overview
End-stage renal disease (ESRD) is characterized by irreversible kidney failure requiring renal replacement therapy, typically dialysis or transplantation, due to loss of nearly all kidney function. Management focuses on preserving vascular access, mitigating cardiovascular risks, and improving quality of life.Diagnosis
Management
Special Populations
Key Recommendations
References
Showing 100 most recent of 902 indexed papers.
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Kidney Transplantation as Curative Therapy for Refractory Dialysis-induced Hypotension: A Case Report and Literature Review. Transplantation proceedings 2026. link 6 Yang C, Singh S, Ogami T, Kirilina D, Wang P, Stevens J et al.. Arterial Grafting Survival Benefit in Patients With End-Stage Renal Disease Undergoing Coronary Artery Bypass Grafting. The Annals of thoracic surgery 2026. link 7 Bołtuć-Dziugieł K, Dziugieł R, Roskal-Wałek J, Bociek A, Terpiłowska S, Dąbrowski W et al.. Cardiovascular implications of osmotic changes during hemodialysis: a potential risk factor. International urology and nephrology 2026. link 8 Miao Y, Chen W, Liao Y, Yao Y, Zhang Y. Impact of 2025 ASE Update Recommendations for the Evaluation of Left Ventricular Diastolic Function in Patients With End-Stage Renal Disease. Echocardiography (Mount Kisco, N.Y.) 2026. link 9 Gubbels M, van Nieuwenhuizen RC, Weijmer MC, Ter Meer M, Wust AFJ. Case series of seven delaminations in an Acuseal haemodialysis graft. The journal of vascular access 2026. link 10 Wang SF, Xu ZJ, Cui TL. A case of surgical treatment combined with interventional therapy for refractory hemodialysis access with catheter-related right atrial thrombosis. The journal of vascular access 2026. link 11 Chow SP, Donelenko S, Coppock C. Case Report: Buprenorphine for Palliation in a Patient with End Stage Renal Disease. Journal of pain & palliative care pharmacotherapy 2025. link 12 Kloppe A, Winter J, Prull M, Aweimer A, El-Battrawy I, Hanefeld C et al.. Subcutaneous cardioverter defibrillator implanted intermuscularly in patients with end-stage renal disease requiring hemodialysis: 5-year follow-up. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2025. link 13 Tozzi M, De Letter J, Krievins D, Jushinskis J, D'Haeninck A, Rucinskas K et al.. First-in-human feasibility study of the aXess graft (aXess-FIH): 6-Month results. The journal of vascular access 2025. link 14 Dawit H, Mehmood S, Hussain Z, Islam SR, Wang Z, Cao Y et al.. Fabrication of nanoparticle-reinforced composite hydrogel for improved durability, antifouling, and thrombosis-resistance in arteriovenous grafts. Colloids and surfaces. B, Biointerfaces 2025. link 15 Weiss R, Yu Q, Funaki B, Hammes M. Recurrent thrombosis and patency of the arteriovenous access in patients receiving hemodialysis. The journal of vascular access 2025. link 16 Huang J, Li Y, Shen S, Yu L, Sun Q. Study on causes of death and influencing factors in hemodialysis patients with End-Stage renal disease. BMC urology 2025. link 17 Jacobs CR, Lanka S, Erben Y, Clendenon J, Alsabbagh Y, Taner CB et al.. Novel modified iliac artery stent graft with side branch extension facilitating kidney transplant in severe aortoiliac occlusive disease. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2025. link 18 Hellwig K, Zicha S, Kopp C, Rother U, Papatheodorou N, Uder M et al.. The Delay of Recanalisation of Acutely Thrombosed Dialysis Arteriovenous Access Until the Next Workday has No Negative Impact on Clinical Outcome. Cardiovascular and interventional radiology 2025. link 19 Byun JH, Rennie A, Huang J, Raja J. Rotational thrombectomy versus balloon maceration in dialysis access salvage. The journal of vascular access 2025. link 20 Lei W, Huang W, Xin J. Successful management of fatal cardiac tamponade resulting from intravascular intervention for central vein occlusion in hemodialysis patients: A case report. The journal of vascular access 2025. link 21 Wu Z, Chen F, Li P, Zhao M. Impact of peritoneal dialysis and hemodialysis on mortality in patients with end-stage renal disease: A systematic review and meta-analysis. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2025. link 22 Zhao N, Zhang T, Zhang T, Wang B, Mu W, Wang F. Effect of blood viscosity on the hemodynamics of arteriovenous fistulae based on numerical investigation. Computer methods in biomechanics and biomedical engineering 2025. link 23 Araki S, Kitagawa K, Nakamura S, Michallek F, Kokawa T, Takafuji M et al.. Integrating myocardial CT perfusion with coronary CT angiography improves risk stratification in patients with dialysis-dependent end-stage renal disease. Japanese journal of radiology 2025. link 24 Wu J, Zeng Y, Yang J, Yao Y, Xu X, Song G et al.. Daily Treatment Monitoring for Patients Receiving Home-Based Peritoneal Dialysis and Prediction of Heart Failure Risk: mHealth Tool Development and Modeling Study. JMIR formative research 2025. link 25 Lin TH, Hung TY, Lin LY, Lin TC, Liou YJ, Hsu YJ et al.. Dipeptidyl Peptidase-4 Inhibitors and Risk of Heart Failure in Patients With Type 2 Diabetes Mellitus and End-Stage Renal Disease Requiring Dialysis. Pharmacoepidemiology and drug safety 2025. link 26 Yan S, Yao D, Wang Y, Zhang J. Risk factors of foot ulcers in patients with end-stage renal disease on dialysis: A meta-analysis. International wound journal 2024. link 27 Zhu Y, Li J, Lu H, Shi Z, Wang X. Effect of hemodiafiltration and hemodialysis on mortality of patients with end-stage kidney disease: a meta-analysis. BMC nephrology 2024. link 28 Alexandra N, Christos A, Miltos LK, George GS. A meta-analysis of vascular access outcomes in hemodialysis patients aged 75 years or older. The journal of vascular access 2024. link 29 Yao L, Ni L, Wu X. Does the Use of Gastric-Acid Suppressants Increase the Risk of Peritonitis in Patients Undergoing Peritoneal Dialysis? A Meta-Analysis. Seminars in dialysis 2024. link 30 Xu S, Wu W, Cheng J. Comparison of outcomes of incremental vs. standard peritoneal dialysis: a systematic review and meta-analysis. BMC nephrology 2024. link 31 Pauw EK, Walsh R. Development of a bleeding arteriovenous fistula task trainer. The Journal of emergency medicine 2024. link 32 Aurora J, Zheng T, Fortunati JR, Erenler F. Megestrol acetate as an overlooked cause of hyperglycemia in end-stage renal disease: A case of polypharmacy. Journal of the American Pharmacists Association : JAPhA 2024. link 33 Sridharan K. Assessment of drug utilization and potentially inappropriate medications in hemodialysis patients with end-stage renal dysfunction: A study in a tertiary care hospital in Bahrain. The International journal of risk & safety in medicine 2024. link 34 Yan Q, Davies MG. Outcomes of one-stage and two-stage aneurysm repair in arteriovenous fistulae. Journal of vascular surgery 2024. link 35 Bozzetto M, Remuzzi A, Valen-Sendstad K. Flow-induced high frequency vascular wall vibrations in an arteriovenous fistula: a specific stimulus for stenosis development?. Physical and engineering sciences in medicine 2024. link 36 Hunderup MM, Kampmann JD, Kristensen FB, Hafsund M. The short-term effect of hemodialysis on the level of high-sensitive cardiac troponin T - A systematic review. Seminars in dialysis 2024. link 37 Ito T, Akamatsu K. Echocardiographic manifestations in end-stage renal disease. Heart failure reviews 2024. link 38 Zhang TY, An DA, Zhou H, Chen B, Lu R, Fang W et al.. Left Ventricular Vertical Run-Length Nonuniformity MRI Adds Prognostic Value to MACE in Patients with End-Stage Renal Disease. Journal of magnetic resonance imaging : JMRI 2024. link 39 Du J, Li Y, Jia X, Kong X, Liang L, Wang D et al.. Elevated c-kit expression in failed autologous arteriovenous fistulas in end-stage renal disease patients. The journal of vascular access 2024. link 40 Hasselbalch RB, Alaour B, Kristensen JH, Couch LS, Kaier TE, Nielsen TL et al.. Hemodialysis and biomarkers of myocardial infarction - a cohort study. Clinical chemistry and laboratory medicine 2024. link 41 Zhang TY, An DA, Fang Y, Zhou H, Yan H, Chen B et al.. Assessment of the Prognostic Value of MRI Left Ventricular Global Function Index (LVGFI) in Patients With End-Stage Renal Disease Under Maintenance Dialysis. Journal of magnetic resonance imaging : JMRI 2024. link 42 Robbin V, Bansal V, Vellanki K, Siddiqui F, Hoppensteadt-Moorman D, Fareed J et al.. Angiopoietin-2 and Mortality Outcomes in End-Stage Renal Disease with Heart Failure as a Comorbidity. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2024. link 43 Karumanchi P, Sridharan D, Hoppensteadt D, Siddiqui F, Fareed J, Bansal V. Thromboinflammatory Biomarkers of Cardiorenal Syndrome in Patients With End-Stage Renal Disease. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2024. link 44 Higgins MCSS, Diamond M, Mauro DM, Kapoor BS, Steigner ML, Fidelman N et al.. ACR Appropriateness Criteria® Dialysis Fistula Malfunction. Journal of the American College of Radiology : JACR 2023. link 45 Puspitasari M, Sattwika PD, Rahari DS, Wijaya W, Hidayat ARP, Kertia N et al.. Outcomes of vaccinations against respiratory diseases in patients with end-stage renal disease undergoing hemodialysis: A systematic review and meta-analysis. PloS one 2023. link 46 Yang Q, Liu K, Ren X, Fang X, Yao L, Wang M et al.. Conscious sedation anesthesia using different doses of remifentanil combined with dexmedetomidine for peritoneal dialysis catheter implantation. Renal failure 2023. link 47 Brecher DB, Hopkins J. The Value of Recreation Therapy in End-of-Life Care: Case Studies From an Inpatient VA Hospice Program. The American journal of hospice & palliative care 2023. link 48 Yu TH, Lu FL, Wei CJ, Wu WW. The impacts of the scope of benefits expansion on hospice care among adult decedents: a nationwide longitudinal observational study. BMC palliative care 2023. link 49 Ernecoff NC, Anhang Price R. Concurrent Care as the Next Frontier in End-of-Life Care. JAMA health forum 2023. link 50 Khanfar O, Aydi R, Saada S, Shehada M, Hamdan Z, Sawalmeh O et al.. Mid-term cumulative patency of fistula and PTFE grafts among hemodialysis patients: A retrospective, single-center study from Palestine. The journal of vascular access 2023. link 51 Baltacı MA, Atmis V, Metin Y, Aktar M, Eren SA, Sengul S et al.. Sarcopenia and cardiovascular risk indices: Its impact on cardiovascular events and mortality in dialysis patients. Seminars in dialysis 2023. link 52 Pande A, Sen IM, Gupta A, Gupta A, Sharma A. Perineural low dexamethasone dose as adjuvant in supraclavicular brachial plexus block for arteriovenous fistula creation in end stage renal disease: a randomized controlled trial. Brazilian journal of anesthesiology (Elsevier) 2023. link 53 Attia MI, Atta EM, Elheneidy MA, Sallam EM. Salvage of infected autogenous arteriovenous fistulas, is it possible?. The journal of vascular access 2023. link 54 Mo H, Ahn S, Han A, Min S, Min SK, Jung IM. Outcome after early thrombotic occlusion of arteriovenous fistulas. The journal of vascular access 2023. link 55 Galarza Tapia A, Velescu A, Collado Nieto S, Cao Baduell H, Ruiz-Carmona C, Mateos Torres E et al.. Kidney transplantation reduces the risk of chronic limb threatening ischemia and amputation among patients with end-stage renal disease on hemodialysis. Vascular 2023. link 56 Ponchia PI, Ahmed R, Farag M, Alkhalil M. Antiplatelet Therapy in End-stage Renal Disease Patients on Maintenance Dialysis: a State-of-the-art Review. Cardiovascular drugs and therapy 2023. link 57 Tang TY, Soon SX, Yap CJ, Tan RY, Pang SC, Patel A et al.. Endovascular salvage of failing arterio-venous fistulas utilising sirolimus eluting balloons: Six months results from the ISABELLA trial. The journal of vascular access 2023. link 58 Kanbay M, Ureche C, Copur S, Covic AM, Tanriover C, Sekmen M et al.. Kidney transplantation: is it a solution to endothelial dysfunction?. International urology and nephrology 2023. link 59 Park BE, Bae MH, Park YJ, Kim HN, Kim N, Jang SY et al.. Preoperative cardiac troponin I as a predictor of postoperative cardiac events in patients with end stage renal disease undergoing non-cardiac surgery. Heart and vessels 2023. link 60 Ariss RW, Alhazmi L, Nazir S, Khouri SJ, Malhotra D, Rees M et al.. Brain-type natriuretic peptide levels and invasive hemodynamic parameters in dialysis dependent patients. The American journal of the medical sciences 2023. link 61 Krishnamurthy S, Sama NR, Soundararajan R. Entrapment of fractured balloon after angioplasty in an AV access using a covered stent. The journal of vascular access 2023. link 62 Soon SX, Tan RY, Pang SC, Yap CJ, Patel A, Gogna A et al.. Ranger™ paclitaxel-coated balloon versus conventional balloon angioplasty for treatment of failing arteriovenous fistulas and grafts in haemodialysis patients: A retrospective cohort study. The journal of vascular access 2023. link 63 Seet C, Lindsey B, Sivaprakasam R, McCafferty K, Forbes S, Akhtar MR et al.. The management of dialysis access thrombosis during the COVID-19 pandemic. The journal of vascular access 2023. link 64 Wang F, Fan X, Kong J, Wang C, Ma B, Sun W et al.. Inhibition of mitochondrial fission alters neo-intimal hyperplasia via PI3K/Akt signaling in arteriovenous fistulas. Vascular 2023. link 65 Suratako S, Matchim Y. Palliative care programmes for people with conditions other than cancer in Thailand: a literature review. International journal of palliative nursing 2023. link 66 Prabu P, Acree L, Waller JL, Linder DF, Bollag WB, Mohammed A et al.. Sleep apnea in end-stage renal disease patients: risk factors and mortality. Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2023. link 67 Shu X, Lin T, Wang H, Zhao Y, Jiang T, Peng X et al.. Diagnosis, prevalence, and mortality of sarcopenia in dialysis patients: a systematic review and meta-analysis. Journal of cachexia, sarcopenia and muscle 2022. link 68 Alessia S, Matilde SF, Chrystel I, Massimiliano S, Daniele D, Claudia F et al.. The quality of palliative sedation in end-stage disease: audit from a department of oncology and haematology. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2022. link 69 Milkowski A, Prystacki T, Marcinkowski W, Dryl-Rydzynska T, Zawierucha J, Malyszko JS et al.. Lack or insufficient predialysis nephrology care worsens the outcomes in dialyzed patients - call for action. Renal failure 2022. link 70 Paneerselvam GS, Aftab RA, Sirisinghe RG, Lai PSM, Lim SK. Study protocol: Effectiveness of patient centered pharmacist care in improving medication adherence, clinical parameters and quality of life among hemodialysis patients. PloS one 2022. link 71 Dyer V, Kirk TW. Engaging the Dignity of Risk in Home Hospice Care. Perspectives in biology and medicine 2022. link 72 Chuang MH, Lee FN, Shiau YT, Shen HY, Lee CC, Chen SS et al.. Physician Palliative Education Associated With High Use of Hospice Care Service. The American journal of hospice & palliative care 2022. link 73 Ahmed Sharif D. The Effectiveness of Vitamin D Supplementation on Oxidative and Inflammatory Markers in Patients Suffering from End-stage Renal Disease, a Randomized Controlled Trial. Cellular and molecular biology (Noisy-le-Grand, France) 2022. link 74 Sousa H, Bártolo A, Ribeiro O, Figueiredo D. A family-centred perspective on the arteriovenous fistula in end-stage renal disease: Findings from dyadic interviews. Scandinavian journal of caring sciences 2022. link 75 Sen I, Tripathi R. Dialysis-associated steal syndromes. The Journal of cardiovascular surgery 2022. link 76 Manov JJ, Mohan PP, Vazquez-Padron R. Arteriovenous fistulas for hemodialysis: Brief review and current problems. The journal of vascular access 2022. link 77 Mandwar M, Seth A, Sharma A, Kenwar DB, Patil SS, Singh S. Outcome of tibio-saphanous arteriovenous fistula in patients with failed upper extremity dialysis access: A report of two cases. The journal of vascular access 2022. link 78 Bautz J, Stypmann J, Reiermann S, Pavenstädt HJ, Suwelack B, Stegger L et al.. Prognostic implication of myocardial perfusion and contractile reserve in end-stage renal disease: A direct comparison of myocardial perfusion scintigraphy and dobutamine stress echocardiography. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2022. link 79 Tasopoulou KM, Argyriou C, Kakkos SK, Mourvati E, Georgakarakos EI, Thodis E et al.. Superficialization Methods of Arteriovenous Fistula in Obese Patients: A Review of the Literature. Annals of vascular surgery 2022. link 80 Grundmann D, Linder M, Goßling A, Voigtländer L, Ludwig S, Waldschmidt L et al.. End-stage renal disease, calcification patterns and clinical outcomes after TAVI. Clinical research in cardiology : official journal of the German Cardiac Society 2022. link 81 Khan MZ, Syed M, Agrawal P, Osman M, Khan MU, Alharbi A et al.. Baseline characteristics and outcomes of end-stage renal disease patients after in-hospital sudden cardiac arrest: a national perspective. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2022. link 82 De Siqueira J, Jones A, Waduud M, Troxler M, Stocken D, Scott DJA. Systematic review of interventions to increase the use of arteriovenous fistulae and grafts in incident haemodialysis patients. The journal of vascular access 2022. link 83 Ghosh NK, Bhattacharjee HK, Prajapati O, Krishna A, Kumar A, Mahajan S et al.. Impact of clinical parameters and vascular haemodynamics on arterio-venous fistula maturation in patients with end stage renal disease: A prospective study on Indian patients. The journal of vascular access 2022. link 84 Zhu F, Yao Y, Ci H, Shawuti A. Predictive value of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio for primary patency of percutaneous transluminal angioplasty in hemodialysis arteriovenous fistula stenosis. Vascular 2022. link 85 Brandt S, Fischer A, Kreutze C, Hempel D, Gorny X, Scurt FG et al.. Midkine release during hemodialysis is predictive of hypervolemia and associates with excess (cardiovascular) mortality in patients with end-stage renal disease: a prospective study. International urology and nephrology 2022. link 86 Qin L, Gu S, Xiao R, Liu P, Yan F, Yu H et al.. Value of native T1 mapping in the prediction of major adverse cardiovascular events in hemodialysis patients. European radiology 2022. link 87 Goldstein J, Dieter RS, Bansal V, Wieschhaus K, Dieter RS, Bontekoe E et al.. Arterial-renal Syndrome in Patients with ESRD, a New Disease Paradigm. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2022. link 88 Jha AK, Lata S. Kidney transplantation in valvular heart disease and pulmonary hypertension: Consensus in waiting. Clinical transplantation 2021. link 89 Lee HJ, Son YJ. Prevalence and Associated Factors of Frailty and Mortality in Patients with End-Stage Renal Disease Undergoing Hemodialysis: A Systematic Review and Meta-Analysis. International journal of environmental research and public health 2021. link 90 Mohamed I, Kamarizan MFA, Da Silva A. Medical adjuvant treatment to increase patency of arteriovenous fistulae and grafts. The Cochrane database of systematic reviews 2021. link 91 Dian S, Simeone M, Rossi B, Scaparrotta G, Fragasso A, Carretta G et al.. Going to war with COVID-19: Strategies for SARS-CoV-2 management in the Padua Nephrology and Dialysis Unit's hemodialysis facility. Clinical nephrology 2021. link 92 Michel LM, Baroux N, Frimat L, Quirin N. Telenephrology and on-site nephrology: Comparable adequate dialysis care to patients living in remote Pacific Islands. Journal of telemedicine and telecare 2021. link 93 Andersen-Hollekim T, Landstad BJ, Solbjør M, Kvangarsnes M, Hole T. Nephrologists' experiences with patient participation when long-term dialysis is required. BMC nephrology 2021. link 94 Chang GH, Lu A, Yang YH, Liu CY, Chang PJ, Lee CP et al.. High Risk of Peritonsillar Abscess in End-Stage Renal Disease Patients: A Nationwide Real-World Cohort Study. International journal of environmental research and public health 2021. link 95 Paik JM, Zhuo M, York C, Tsacogianis T, Kim SC, Desai RJ. Medication Burden and Prescribing Patterns in Patients on Hemodialysis in the USA, 2013-2017. American journal of nephrology 2021. link 96 Xiong B, Freeman S, Banner D, Spirgiene L. Hospice Utilization Among Residents in Long-Term Care Facilities. Journal of palliative care 2021. link 97 Chen HC, Wu CY, Hsieh HY, He JS, Hwang SJ, Hsieh HM. Predictors and Assessment of Hospice Use for End-Stage Renal Disease Patients in Taiwan. International journal of environmental research and public health 2021. link 98 Alshahawey M, El Borolossy R, El Wakeel L, Elsaid T, Sabri NA. The impact of cholecalciferol on markers of vascular calcification in hemodialysis patients: A randomized placebo controlled study. Nutrition, metabolism, and cardiovascular diseases : NMCD 2021. link 99 Tan CW, Tan RY, Pang SC, Tng ARK, Tang TY, Zhuang KD et al.. Single-Center Prospective Pilot Study of Sirolimus Drug-Coated Balloon Angioplasty in Maintaining the Patency of Thrombosed Arteriovenous Graft. Journal of vascular and interventional radiology : JVIR 2021. link 100 Georgakarakos E, Tasopoulou KM, Georgiadis GS. Introducing a "no-touch" maneuver to manage challenging anastomoses in arteriovenous fistulae. The journal of vascular access 2021. link