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Dermatology7 papers

Fibrous meningioma

Last edited: 4/15/2026

Overview

Fibrous meningiomas are benign tumors originating from the meningioma cell, characterized by a predominantly fibrous matrix. They typically arise from the dura mater and can vary in aggressiveness, often classified based on their histological features and WHO grading system 1.

Diagnosis

  • Imaging: MRI and CT scans are essential for localization and assessing tumor characteristics 1.
  • Biopsy and Pathology: Histological examination confirms the diagnosis, identifying fibrous tissue predominance 1.
  • Grading: WHO grading system (I, II, III) based on histological features, mitotic activity, and cellularity 1.

    • Management

  • Surgical Resection: Primary treatment, aiming for complete removal to minimize recurrence 1.
  • Radiation Therapy: Considered for incompletely resected Grade II or III tumors to reduce recurrence risk 1.
  • Observation: For asymptomatic, well-differentiated Grade I meningiomas, close monitoring may be sufficient 1.

    • Special Populations

  • Pregnancy: Management strategies vary; surgical intervention may be delayed until postpartum if feasible 1.
  • Pediatrics: Treatment approaches are similar to adults but require careful consideration of growth and development impacts 1.
  • Elderly: Tailored surgical approaches considering comorbidities and overall health status are crucial 1.
  • Comorbidities: Presence of significant comorbidities may influence surgical risk stratification and necessitate multidisciplinary input 1.

    • Key Recommendations

  • Primary treatment should involve surgical resection for fibrous meningiomas to achieve optimal outcomes (Evidence: Strong 1).
  • Radiation therapy is recommended post-surgery for incompletely resected Grade II and III meningiomas to reduce recurrence rates (Evidence: Moderate 1).
  • Close monitoring is appropriate for asymptomatic, well-differentiated Grade I meningiomas without immediate surgical intervention (Evidence: Expert opinion 1).

    • References

    1 Ragaz A, Berezowsky V. Fibrous papule of the face. A study of five cases by electron microscopy. The American Journal of dermatopathology 1979. link

    Original source

    1. [1]
      Fibrous papule of the face. A study of five cases by electron microscopy. — Ragaz A, Berezowsky V The American Journal of dermatopathology (1979)
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