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Emergency Medicine3 papers

Infantile lobar overinflation of lung

Last edited: 4/10/2026

Management

  • Sustained lung inflations (SI) for more than 5 seconds are not beneficial for preterm infants at birth 1.
  • The use of SI may increase mortality in preterm infants 1.
  • Special Populations

  • Preterm infants: The evidence reviewed pertains to preterm newborns, specifically those ≤28+0 weeks' gestation 1.
  • Key Recommendations

  • Sustained lung inflations (SI) for more than 5 seconds should not be used for preterm infants at birth 1. (Evidence: Strong)
  • Avoid sustained lung inflations (SI) in preterm infants due to a potential increase in mortality 1. (Evidence: Strong)
  • References

    1 Kapadia VS, Urlesberger B, Soraisham A, Liley HG, Schmölzer GM, Rabi Y et al.. Sustained Lung Inflations During Neonatal Resuscitation at Birth: A Meta-analysis. Pediatrics 2021. link

    Original source

    1. [1]
      Sustained Lung Inflations During Neonatal Resuscitation at Birth: A Meta-analysis.Kapadia VS, Urlesberger B, Soraisham A, Liley HG, Schmölzer GM, Rabi Y et al. Pediatrics (2021)

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