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Endocrinology18 papers

Congenital gastric perforation

Last edited: 4/15/2026

Overview

Congenital gastric perforation is a rare but serious condition characterized by a hole in the stomach wall present at birth or shortly thereafter. Acquired cases, such as those following endoscopic procedures or foreign body ingestion, also occur 12.

Diagnosis

  • Clinical signs include acute abdominal pain, distension, and signs of peritonitis.
  • Imaging studies (ultrasound, CT) are crucial for confirming perforation and assessing extent of peritonitis 12.
  • Contrast studies (upper GI series) may reveal the perforation site 1.
  • Management

  • Surgical intervention: Primary repair or resection/re-anastomosis is often necessary for definitive treatment 12.
  • Supportive care: Fluid resuscitation, broad-spectrum antibiotics to prevent infection 1.
  • Endoscopic management: For certain cases, endoscopic retrieval of foreign bodies may be attempted, though surgical backup is often required 2.
  • Special Populations

  • Pediatrics: Congenital cases are more common; surgical expertise in pediatric surgery is crucial 1.
  • Comorbidities: Presence of other conditions may complicate management; individualized care plans are essential 1.
  • Key Recommendations

  • Immediate surgical consultation and intervention are recommended for confirmed cases of gastric perforation to prevent sepsis and ensure survival (Evidence: Strong 1).
  • In cases involving foreign bodies causing perforation, endoscopic removal should be considered as a first-line approach when feasible, with surgical readiness as a contingency (Evidence: Moderate 2).
  • Broad-spectrum antibiotic coverage should be initiated promptly to mitigate infection risk in all perforated gastric cases (Evidence: Expert opinion 1).
  • References

    1 Roche-Nagle G, Mulligan E, Connolly E, Lane B. Unusual cause of a perforated stomach. Annals of the Royal College of Surgeons of England 2003. link 2 Lee YK, Chae SI, Cho WS. Endoscopic extraction of a perforating wire from the stomach. The Korean journal of internal medicine 1987. link

    Original source

    1. [1]
      Unusual cause of a perforated stomach.Roche-Nagle G, Mulligan E, Connolly E, Lane B Annals of the Royal College of Surgeons of England (2003)
    2. [2]
      Endoscopic extraction of a perforating wire from the stomach.Lee YK, Chae SI, Cho WS The Korean journal of internal medicine (1987)

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