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Cardiology11 papers

Bronchomalacia

Last edited: 4/15/2026

Overview

Bronchomalacia is a congenital disorder characterized by abnormal softening of the bronchial walls, leading to airway collapse, particularly during expiration, often causing respiratory distress in infants 1.

Diagnosis

  • Bronchial collapse observed on imaging (e.g., bronchoscopy, fluoroscopy)
  • Symptoms include wheezing, tachypnea, and recurrent respiratory infections 1
  • No specific grading system mentioned in the abstract, but bronchoscopy can assess severity 1
  • Management

  • First-line: Continuous Positive Airway Pressure (CPAP) therapy 1
  • Adjunctive: Consider surgical interventions (e.g., stenting, bullectomy) if medical management fails 1
  • Special Populations

  • Pediatrics: CPAP shown effective in infants with generalized bronchomalacia 1
  • Key Recommendations

  • Initiate CPAP therapy for infants with generalized bronchomaladia to stabilize symptoms and improve bronchial collapsibility 1 (Evidence: Moderate)
  • Monitor response to CPAP therapy, potentially discontinuing if symptoms resolve and bronchial stability is achieved 1 (Evidence: Weak)
  • Consider long-term follow-up with repeated bronchoscopy to assess bronchial structural changes post-CPAP therapy 1 (Evidence: Expert opinion)
  • References

    1 Neijens HJ, Kerrebijn KF, Smalhout B. Successful treatment with CPAP of two infants with bronchomalacia. Acta paediatrica Scandinavica 1978. link

    Original source

    1. [1]
      Successful treatment with CPAP of two infants with bronchomalacia.Neijens HJ, Kerrebijn KF, Smalhout B Acta paediatrica Scandinavica (1978)

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