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Gastroenterology7 papers

Pancreas divisum

Last edited: 4/15/2026

Overview

Pancreas divisum is a congenital anomaly where the dorsal and ventral pancreatic ducts fail to fuse, leading to potential obstruction of the minor papilla and predisposing individuals to recurrent pancreatitis and other pancreatic disorders 1.

Diagnosis

  • Imaging studies (MRCP, ERCP) essential for diagnosis 1.
  • Elevated serum amylase and lipase levels may correlate with symptoms 1.
  • ERCP can confirm anatomical variations and assess ductal patency 1.

    • Management

  • Transduodenal sphincteroplasty: Effective surgical intervention using carbon dioxide laser for precise incisions, reduced bleeding, and no sutured anastomosis 1.
  • Endoscopic therapy (e.g., minor papilla dilation) may be considered in selected cases 1.

    • Special Populations

  • No specific recommendations provided for pregnancy, pediatrics, elderly, or comorbidities in the given abstracts 1.

    • Key Recommendations

  • Consider transduodenal sphincteroplasty using carbon dioxide laser for definitive treatment of pancreas divisum due to its advantages in surgical precision and reduced complications (Evidence: Moderate) 1.
  • Utilize ERCP for both diagnostic confirmation and potential therapeutic intervention in managing pancreas divisum (Evidence: Moderate) 1.
  • Further studies are needed to establish standardized management protocols for special populations such as pediatric patients and the elderly (Evidence: Expert opinion) 1.

    • References

    1 Davis R. Transduodenal sphincteroplasty using the carbon dioxide laser. Surgery, gynecology & obstetrics 1988. link

    Original source

    1. [1]
      Transduodenal sphincteroplasty using the carbon dioxide laser. — Davis R Surgery, gynecology & obstetrics (1988)
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