Overview
Superficial spreading melanoma (SSM) is the most common subtype of melanoma, characterized by radial growth along the epidermis and superficial dermis 1. It typically presents as a macule or plaque with irregular borders and variable pigmentation 1.Diagnosis
Diagnosis is primarily based on clinical examination, often aided by dermoscopy 1.
Biopsy with histopathological examination is required for definitive diagnosis and staging 1.Management
Surgical excision with adequate margins is the primary treatment for SSM 1.
Adjuvant therapy decisions are based on tumor characteristics, including Breslow depth, ulceration, and nodal status 1.Key Recommendations
Surgical excision with appropriate margins is recommended for the treatment of superficial spreading melanoma 1. (Evidence: Expert opinion)
Adjuvant therapy should be considered for patients with melanoma based on prognostic factors such as Breslow depth and ulceration 1. (Evidence: Expert opinion)
Guidelines should be periodically updated to reflect current clinical practices and incorporate regional data, particularly regarding differences in melanoma subtypes and drug efficacy between Western and East Asian populations 1. (Evidence: Expert opinion)References
1 Fukushima S, Ito T, Asai J, Igaki H, Tanaka R, Namikawa K et al.. Japanese Dermatological Association Guidelines: Clinical Questions of Guidelines for Melanoma 2025. The Journal of dermatology 2025. link