Overview
Heart disease encompasses a broad spectrum of conditions affecting the heart, including coronary artery disease, valvular disorders, and structural abnormalities, significantly impacting morbidity and mortality globally.Diagnosis
Management
Special Populations
Key Recommendations
References
Showing 100 most recent of 8869 indexed papers.
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Current opinion in cardiology 2026. link 4 Ding X, Bai J, Jiang W, Li Y, Zhang S. Individualised Empowerment in Secondary Cardiac Rehabilitation in Patients With Coronary Heart Disease: A Qualitative Study. Inquiry : a journal of medical care organization, provision and financing 2026. link 5 Tanguay P, Marquis N, Faivre P, Registe PPW, Boucher SM, Laevski K et al.. Distinguishing Hybrid Cardiac Rehabilitation Models and Comparing Their Effectiveness: A Systematic Review. Journal of cardiopulmonary rehabilitation and prevention 2026. link 6 Long L, Lin CZ, Davies P, Wells V, Grace SL, Taylor RS. Interventions to promote patient utilisation of cardiac rehabilitation. The Cochrane database of systematic reviews 2026. link 7 Liu Y, Wang X, Li J, Huang X, Yu J, Chen M. Effects of personalized structured telemedicine-based exercise cardiac rehabilitation on health outcomes in patients with coronary heart disease: a systematic review and meta-analysis. European journal of cardiovascular nursing 2026. link 8 Yuan L, Li Y, Jiang X, Yang Z. A journey map for improving the cardiac rehabilitation experience and care quality of patients with coronary heart disease: A longitudinal qualitative study. International journal of nursing studies 2026. link 9 Gadager BB, Tang LH, Sevel C, Doherty P, Harrison A, Maribo T. Change in exercise capacity after cardiac rehabilitation following coronary heart disease in patients with and without diabetes: A follow-up study. International journal of cardiology 2026. link 10 Khaiser UF, Sultana R, Das R, Alzahrani SG, Kannan M, Newigy MK et al.. Prevalence of polypharmacy and drug interactions in geriatric patients: A cross-sectional study from India. PloS one 2026. link 11 Lo M, Amin AK, Kowalski M, Kroman A, Mathew D, Parikh V et al.. Leadless Versus Transvenous Dual-Chamber Pacemakers: Real-World Evidence From AVEIR DR Coverage With Evidence Development Study. Journal of cardiovascular electrophysiology 2026. link 12 Du MY, Lyu MK, Liu HL, Li YZ, Yan HF, Li XH. Machine Learning-Based Risk Prediction for Coronary Heart Disease Complicated by Hyperhomocysteinemia: Retrospective Study. JMIR medical informatics 2026. link 13 Zhang B, Furtado JD, Andraski AB, Guglielmo B, Appel LJ, Wang K et al.. Partially Replacing Dietary Carbohydrate With Unsaturated Fat or Protein Shifts Protein-Based HDL Subspecies Toward Lower Coronary Heart Disease Risk. Arteriosclerosis, thrombosis, and vascular biology 2026. link 14 Naganuma T, Ouchi T, Yuki H, Nabuchi M, Hozawa K. Bail-Out Navitor in Navitor for Higher Radial Force. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2026. link 15 Wu X, Liu L, Huang Y, Ling Y, Luo F, Gu D et al.. Grhl3 Downregulation Facilitates ECM Adaptation for Fibroblast to iCM Commitment. Circulation research 2026. link 16 Prieto G, Vanegas J, Garcia D, Ortiz AH, Montes L. The "Commando" Procedure in Colombia: Early and Mid-Term Outcomes From the Largest Latin American Series. Interdisciplinary cardiovascular and thoracic surgery 2026. link 17 Turner D, Mehdizadeh-Shrifi A, Raees A, Lehenbauer D, Ashfaq A, VandenHeuvel K et al.. Contrasting the Performance of a Surgeon-Fashioned Extracellular Matrix Cylindrical Tricuspid Valve Versus a Mechanical Valve. World journal for pediatric & congenital heart surgery 2026. link 18 Zhao C, Huang Y, Ma T, Cheng X, Li J, Zhang G et al.. Association of hematopoietic loss of Y chromosome with valvular heart disease incidence and sex susceptibility. Journal of advanced research 2026. link 19 Xu T, Wong S, Le GH, Dri CE, Teopiz KM, Lu A et al.. Cardiac Consequences Associated with Psychedelic Use: A Systematic Review of Lysergic Acid Diethylamide, 3,4-Methylenedioxymethamphetamine, and 5-Hydroxytryptamine 2B-Mediated Valvular Heart Disease. Pharmacopsychiatry 2026. link 20 Okazaki N, Baba Y, Ochi Y, Kawaguchi J, Hirakawa D, Kubo T et al.. Visualization of the True Left Ventricular Apex on Transthoracic Echocardiography. Echocardiography (Mount Kisco, N.Y.) 2026. link 21 Wang ZM, Lian XQ, Long Q, Wu B, Wang LS. Black tea consumption and the risk of coronary heart disease: a systematic review and meta-analysis of cohort studies. Nutrition, metabolism, and cardiovascular diseases : NMCD 2026. link 22 Grams L, Kueck M, Sundermeier T, Haufe S, Nelius AK, Kerling A et al.. Influence of Restrictions During COVID-19 Pandemic on Physical Activity and Quality of Life in Cardiovascular, Kidney Transplant and Healthy Adults. International journal of environmental research and public health 2026. link 23 Ren L, Ahn S. Dyadic Coping, Resilience and Post-Traumatic Growth in Young and Middle-Aged Coronary Heart Disease Patients and Their Spousal Caregivers: An Actor-Partner Interdependence Mediation Model. Journal of advanced nursing 2026. link 24 Androshchuk V, Long E, Chehab O, Montarello N, Wilcox J, McDonaugh B et al.. The Prognostic Value of Right Ventricle-Pulmonary Artery Coupling in Valve Interventions: Systematic Review and Meta-Analysis. JACC. Cardiovascular interventions 2026. link 25 Schlömicher M, Prümmer K, Haldenwang P, Moustafine V, Berres D, Bechtel M et al.. Conduction Disorders after Rapid Deployment Aortic Valve Replacement Compared to Conventional Aortic Valve Replacement. The Thoracic and cardiovascular surgeon 2026. link 26 Tadjeddine F, El Amine DSM, Fadia M. A hybrid discrete wavelet transform (DWT)-principal component analysis (PCA) approach for discriminative feature selection in heart valve diseases. Journal of medical engineering & technology 2026. link 27 Kaur K, Abu-Qamar MZ, Rashidi A, McKay N, Saunders R. Perceptions of ischaemic heart disease risk among Indian migrants in Australia: a qualitative study. Primary health care research & development 2026. link 28 Zisou C, Calvin C, Taylor H, Lacey B, Hammami I, Walmsley R et al.. Reproducibility and associated regression dilution bias of accelerometer-derived physical activity and sleep in UK Biobank. International journal of epidemiology 2026. link 29 Yajima S, He H, Elde S, Zhu Y, Woo YJ, Shudo Y. Survival Benefit of Heart-Kidney Versus Heart Transplant With or Without Delayed Kidney Transplant. Journal of the American Heart Association 2026. link 30 Blandino R, Manuri L, Bruno P, Ragni L, Piccinelli E, Pilati M et al.. The Use of Pulmonary Vasodilators in Pediatric Patients with Single-Ventricle Palliation: A Ten-Year Experience in a Tertiary Care Center. Pediatric cardiology 2026. link 31 Aborkhees GA, Barr AJ, Dietrich K, Male C, Wang Z, Yao C et al.. Ex Vivo Effect of Apixaban on Hemostatic Biomarkers in Children With Heart Disease: A SAXOPHONE Trial Substudy. Journal of the American Heart Association 2026. link 32 Sarraf M, Chehab O, Nagaraja V. Understanding the Pressure-Volume Loop in Valvular Heart Disease. Heart, lung & circulation 2026. link 33 Naito N, Takagi H. Comparative Efficacy of Antithrombotic Strategies in Bioprosthetic Aortic Valve Replacement: A Network Meta-Analysis. Angiology 2026. link 34 Li M, Wang Y, Widdop RE. Novel angiotensin receptor target as therapy for the diabetic heart: the AT. Journal of molecular and cellular cardiology 2026. link 35 Arif S, Son SH, Kim HY, Kim SC, Lee JY. A diagnosis tool for early detection and classification of heart disease in individuals using transformer mechanisms. Computer methods and programs in biomedicine 2026. link 36 Dykun I, Russo G, Mahabadi AA, Thiele H, Alessandrini H, Andreas M et al.. Incidence, Predictors and Outcomes of Bleeding Following Transcatheter Tricuspid Valve Repair: The TriValve Registry. JACC. Cardiovascular interventions 2026. link 37 Gold C, Gausz FD, Vagvolgyi A, Hecker F, Kupusovic J, Miklos M et al.. Efficacy and safety of the subcutaneous implantable cardioverter defibrillator in patients with and without obesity: An international, bicentric retrospective registry. Clinical research in cardiology : official journal of the German Cardiac Society 2026. link 38 Javed A, Javaid N, Saudagar AKJ, Pamucar D. Developing a novel framework using optimized active stacking and explainable AI for heart disease prediction. Computer methods and programs in biomedicine 2026. link 39 Docherty KF, Otto CM, McMurray JJV. Valvular heart failure: evolving pharmacological approaches. European heart journal 2026. link 40 Begum SS, Swamy A, Dhanka S, Abu-Shareha AA, Khan M, Husain I. Generative adversarial networks and hyperparameter-optimized XGBoost for enhanced heart disease prediction. Scientific reports 2026. link 41 Hulsurkar MM, Ong I, Keefe JA, Abu-Taha IH, Dobrev D, Wehrens XHT. Cyclic AMP-dependent regulation of ryanodine receptors in healthy and diseased hearts. Journal of molecular and cellular cardiology 2026. link 42 Arakaki R, Ohno N, Marui A. Pseudoaneurysm of the Mitral-Aortic Intervalvular Fibrosa: A Complication Following Aortic Valvuloplasty. Interdisciplinary cardiovascular and thoracic surgery 2026. link 43 Kuklina EV, Jackson SL, Chang TE, Valteau T, Loustalot F, Wright JS et al.. Heart Disease Among Pregnant Women in the United States: Data, Challenges, and Opportunities for Collaboration. Journal of women's health (2002) 2026. link 44 Shi H, Shu S, Chen X, Chen X, Wang X, Wang W et al.. Valvular Leaflets Are Not Innocent Bystanders: Divergent Fibrotic Remodeling Accompanies Functional Mitral and Tricuspid Regurgitation. Arteriosclerosis, thrombosis, and vascular biology 2026. link 45 Liu Y, Liu F, Xu M, Zhou H, Wang H, Liu Y et al.. Peri-operative rehabilitation in patients undergoing elective cardiac valve surgery: a randomised controlled trial. Anaesthesia 2026. link 46 Holmes SA, Young K, Wolfe KR, Londono-Obregon C, Cuneo BF, Bucholz EM. Maternal-Fetal Environment and Neurodevelopment in Patients with Single Ventricle Heart Disease. The Journal of pediatrics 2026. link 47 Malahfji M, Saeed M, Nguyen DT, Kaolawanich Y, Lababidi H, Gabr EM et al.. Cardiac Remodeling and Outcomes of Patients With Combined Aortic and Mitral Regurgitation. JACC. Cardiovascular imaging 2026. link 48 Yang M, Lin J, Zheng Y, Zhang H, Yu P. Influencing factors of physical activity among young and middle-aged patients with coronary heart disease: a multicenter cross-sectional study. Frontiers in public health 2026. link 49 Nakamaru R, Kohno T, Mizuno A, Nakazawa Y, Miyashita M, Morita T et al.. Bereaved family members-reported distressing symptoms in terminally ill patients with heart disease. Journal of cardiology 2026. link 50 Oliver S, Conway J, Khoury M, Eurich D, Dubois C, Bedard K et al.. Posttransplant outcomes with prolonged donor heart ischemic time in the pediatric population. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2026. link 51 Jiang Q, Niu R, Jiang J, Hu H, He S, Wang H et al.. Association and predictive value of immunoglobulin and complement levels for incident coronary heart disease: a nested case-control study in Chinese adults. European journal of preventive cardiology 2026. link 52 Power A, Dipchand AI. Unique Challenges in Paediatric Heart Transplantation. The Canadian journal of cardiology 2026. link 53 Choi HW, Zhang HS, Shim JK, Cho JS, Ko SH, Kwak YL. Associations between persistent postoperative anaemia and mortality 1 year after valvular heart surgery: a retrospective cohort study. Anaesthesia 2026. link 54 Maciorowska M, Zhang L, Khalique OK. Multimodal Imaging Assessment of Tricuspid Regurgitation and the Right Ventricle. Cardiology clinics 2026. link 55 Huo S, Pulido TR, Archer RS, Fisher JB, Douglas JA. Heat and socioeconomic deprivation compound to drive coronary heart disease in Los Angeles. Frontiers in public health 2026. link 56 Belani K, Mackensen GB. Echocardiography in structural heart disease. Current opinion in anaesthesiology 2026. link 57 Wu L, Shen S, Qian C, Wu N, Qiu X, Hou H. Extracellular vesicles for heart repair: origins, functions, bioengineering strategies, and therapeutic potential. Journal of materials chemistry. B 2026. link 58 van der Bijl P, Ajmone Marsan N, Bax JJ. Controversies in valvular heart disease: insights from cardiac imaging. Trends in cardiovascular medicine 2026. link 59 Zhou Z, Ye G, Ren X, Cheng Y, Cang Y, Zhao J et al.. Relation of serum uric acid with the risk of coronary heart disease: an updated systematic review and dose-response meta-analysis of epidemiologic studies. Frontiers in endocrinology 2026. link 60 Liu X, Zhu Y, Qin Y, Huang Y, Qian X, Xue F et al.. Therapeutic efficacy and safety of Shexiang Baoxin Pill in relation to anxiety and depression in patients with coronary heart disease. Medicine 2026. link 61 Patasova K, Sedaghati-Khayat B, Knevel R, Cordell HJ, Pratt AG. Methods for Prioritizing Causal Genes in Molecular Studies of Human Disease: The State of the Art. Genetic epidemiology 2026. link 62 Bowman HC, Tang JJ, Thein AS, Dewland TA, Marcus GM. Relationship between cardiac implantable electronic devices and tricuspid regurgitation in the general population. Heart rhythm 2026. link 63 Peng Q, Li C, Shao Y, Hou X, Hu M. Analysis of current status and influencing factors of fear of recurrence in patients with coronary heart disease after PCI: A cross-sectional study. Medicine 2026. link 64 Tolani M, AlZahrani Y, Suman G, Kumar P, Balodi A, Bajpai A. Clustering-cum-regression based model and performance analysis for early prediction of heart disease. Scientific reports 2026. link 65 Guo R, Sun M, Lin W, Jiang C, Yang H, Dou J et al.. Association between neck circumference to height ratio and coronary heart disease: a case-control study in a Northern Chinese female population. Scientific reports 2026. link 66 Habboush S, Elmoursi A, Gadelmawla AF, Masoud AT, Khalil M, Sheashaa H et al.. Transvenous Compared With Leadless Pacemakers: A meta-analysis comparing TP versus LP. Cardiology in review 2026. link 67 Dhingra NK, Lee G, Cusimano RJ. Tumours of the heart valves. Current opinion in cardiology 2026. link 68 Yusufu M, Vingrys AJ, Wang B, Shang X, Zhang L, Shi D et al.. Neurovascular retinomics for predicting heart diseases. Cardiovascular research 2026. link 69 Mayurapak C, Bunsuk C, Suwanno J, Koson N, Kumanjan W, Phonphet C et al.. Psychometric Testing of the Self-Care Self-Efficacy Scale Version 3.0 in Thai Patients With Heart Disease. The Journal of cardiovascular nursing 2026. link 70 Li X, Chen L, Jin Z, Yang Z, Cai X, Li F et al.. Changes in physical activity behaviors and influencing factors among children and adolescents with heart disease after hospital discharge: a 3-month follow-up study. European journal of pediatrics 2026. link 71 Mugnai G, Genovese D, Tomasi L, Gambaro A, Ribichini F. The implantable cardioverter-defibrillators at the end of life: a double-edged sword of a life-saving technology. Trends in cardiovascular medicine 2026. link 72 Martens A, Gauvreau K, Smith T, Perez JM, Cox JE, Antonelli R et al.. Intersection of paediatric heart disease and foster care status: a multicentre retrospective cohort study. BMJ paediatrics open 2026. link 73 Yang Z, Feng S, Zhang Z, Ning X, Guo L, Du Y et al.. Cardiac lymphatic system and coronary heart disease: associations, mechanisms and therapeutic strategies. European journal of pharmacology 2026. link 74 Szuba R, Hoffmann TJ, Whooley MA, Elnaggar A, Johnson J, Park LG. The Relationship of Physical Activity With Quality of Life and Perceived Health in Adults With Coronary Heart Disease. The Journal of cardiovascular nursing 2026. link 75 Wang N, Yi H, Yang J, Aierken A, Wushouer H, Han S et al.. The effect of diagnosis-related group policy on treatment cost and treatment efficiency of inpatients with coronary heart disease in Xinjiang: an interrupted time series analysis. Journal of global health 2026. link 76 Earl M, Bhandari R. Assessing the association between cannabis use frequency and heart disease in adults aged under 50: National Survey on Drug Use and Health, 2021-2023. Preventive medicine 2026. link 77 Winter RL, Tillson DM, Maneval KL, Rajeev M, Castro D. Treatment of supravalvular mitral stenosis in a kitten with hybrid balloon angioplasty. Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology 2026. link 78 Porrello ER, Lee CJM, Foo RSY, Elliott DA. Transcriptional regulation in heart development, disease and regeneration: reassessing the fetal gene hypothesis. Nature reviews. Cardiology 2026. link 79 Malara S, Burzotta F, Graziani F, Bianchini F, Scorza V, Romagnoli E et al.. Evolution and long-term impact of concomitant valvulopathies in patients undergoing transcatheter aortic valve implantation. Minerva cardiology and angiology 2026. link 80 Gyoten T, Miyama Y, Kumagai Y, Kanazawa Y, Kuroda T, Akatsu T et al.. Mid-term outcomes and hemodynamic performances of Abbott Epic mitral bioprosthesis: a single-center study. General thoracic and cardiovascular surgery 2026. link 81 Sun S, Zhang Y, Yi S. Effects of artificial sweeteners on coronary heart disease: A 2-way 2-sample Mendelian randomization study and mediation analysis. Medicine 2026. link 82 Ruberti A, Flores-Umanzor E, Sanchis L, Pilgrim T, Regueiro A, Garot P et al.. Transcatheter Mitral and Aortic Paravalvular Leak Closure: Innovations, Challenges, and Future Directions. Circulation. Cardiovascular interventions 2026. link 83 Kempton H, Stolz L, Stocker T, Doldi PM, Weckbach L, Novotny J et al.. Hypoattenuated Leaflet Thickening and Reduced Leaflet Motion After Transcatheter Tricuspid Valve Replacement. JACC. Cardiovascular interventions 2026. link 84 Perelman MG, Laufer-Perl M, Banai A, Avivi I, Shacham Y, Banai S et al.. Mildly elevated left ventricular outflow tract gradients are associated with increased short-term mortality in inpatients without septal hypertrophy. International journal of cardiology 2026. link 85 Guo L, Shi X, Wang G, Han W, Ding R, Wang S et al.. Combined B-vitamin supplementation on homocysteine and vascular outcomes in coronary heart disease: a meta-analysis. Annals of medicine 2026. link 86 Lampropoulos K, Penteris M, Gerotziafas G. Direct Oral Anticoagulants in Valvular Diseases and Prosthetic Valves: Why Not?. Cardiovascular drugs and therapy 2026. link 87 Wang C, Shao X, Wang J, Shi R, Han M, Feng H et al.. New perspectives on the mechanisms and treatment of valvular heart disease: Mendelian randomization and systematic analysis based on plasma proteins. Medicine 2026. link 88 Wang K, Fan J, Mei L. The risk factors associated with pulmonary hypertension in patients with left heart diseases. Medicine 2026. link 89 Alexandrino FB, Schlesinger R, Bird J, Lee E, Deshmukh AJ, Nkomo VT et al.. Integrating AI-ECG and point-of-care cardiac ultrasound for screening structural heart disease: A proof-of-concept study. American heart journal 2026. link 90 Sivaraj E, Lovstakken L, Corney R, Fadnes S, Espeland T, Andresen K et al.. Mechanical Wave Analysis at High Frame-Rate Echocardiography: Feasibility, Determinants, and Normal Ranges. JACC. Cardiovascular imaging 2026. link 91 Tesha I, Qi M, JiaSi W, Xizhe Z, Kombo A, Njoka I et al.. Artificial Intelligence driven prediction of multiple outcomes in older adults with coronary heart disease. The Gerontologist 2026. link 92 Hou Y, Cao C, Guo J, Du P, Li D, Yuan P et al.. From the Laboratory to the Clinic: Differentiation, Disease Modeling and Transplantation of Cardiac Organoids. Advanced healthcare materials 2026. link 93 Purlee MS, Beduschi T, Jacobs JP, De Faria W, Peek GJ, Bilgili A et al.. A Single-Center Experience With En-Bloc Combined Heart+Liver Transplantation: Analysis of Eight Cases, Including Two Heart+Liver+Kidney Transplants. World journal for pediatric & congenital heart surgery 2026. link 94 Alonso-Perez E, O'Sullivan JL, Heisig JP, Correll CU, Steinhagen-Thiessen E, Rudolf H et al.. Is there a compression of morbidity and does it vary across social strata among older European adults? A retrospective cohort study of two waves 15 years apart. Archives of gerontology and geriatrics 2026. link 95 Zheng Y, Yang JJ, Gupta DK, Herrington DM, Yu B, Nguyen NQH et al.. Circulating gut microbial metabolites and risk of coronary heart disease: A prospective multi-stage metabolomics study. PLoS medicine 2026. link 96 Broschmann D, Nebel L, Kleinert E, Mohacsi L, Sadlonova M, Traylor C et al.. "If You Look Closely, You Have Everything …": Ideas of a Good Life Among Middle-Aged Individuals With Heart Disease: An Interpretative Phenomenological Analysis. Qualitative health research 2026. link 97 Hua L, Pang S, Zhang Z, Chen J, Qiu J, Wang Q et al.. Long-term outcomes of tricuspid valve plasty vs. replacement after cardiac surgery: Mortality, reoperation, and anticoagulation complications in patients with postoperative tricuspid regurgitation. International journal of cardiology 2026. link 98 Jeong HK, Kim SS, Kim HK, Ki YJ, Choi DH, Park KH. Assessing modified chest leads as a substitute for electrophysiological systems in left bundle branch area pacing. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2026. link 99 Li Z, Li X, Zhou X, Song X, Lei J, Zhang W. Exercise motivation mediates the relationship between basic psychological needs and exercise adherence in older adults with coronary heart disease. Heart & lung : the journal of critical care 2026. link 100 Li J, Liu P, Li H, Bian B. Coronary heart disease offspring: identification of short-term cardiovascular risk factors and construction of digital technology-integrated personalized health education pathways. BMC cardiovascular disorders 2026. link