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Cardiology1059 papers

Microcystic renal disease

Last edited: 4/23/2026

Overview

Microcystic renal disease refers to a spectrum of renal disorders characterized by the development of microcysts within the renal parenchyma, often leading to progressive renal dysfunction. The condition can be associated with various underlying etiologies, including genetic factors and systemic diseases, though specific guidelines focusing solely on microcystic renal disease are not directly addressed in the provided abstracts.

Diagnosis

  • Imaging studies (CT, MRI) to identify microcysts within the renal parenchyma 1117.
  • Renal biopsy may be necessary to rule out other specific renal pathologies and assess histopathological features 22.
  • Laboratory tests including serum creatinine, blood urea nitrogen (BUN), and urinalysis to evaluate renal function and detect proteinuria or hematuria 622.
  • Doppler ultrasound to assess renal artery complications or vascular involvement 1070.
  • Management

  • Treatment often targets underlying causes; specific drug classes are not extensively detailed in the abstracts 125.
  • Angioplasty or embolization may be considered for vascular complications affecting renal function 2244.
  • Management of hypertension and fluid balance to mitigate further renal damage 18.
  • Supportive care including dialysis if renal function declines significantly 22.
  • Special Populations

  • Pediatrics: Limited specific guidance; renal biopsy and imaging are crucial for diagnosis 22314.
  • Elderly: Consideration of comorbidities and polypharmacy risks in treatment planning 4557.
  • Comorbidities: Management strategies should account for concurrent cardiovascular disease, diabetes, and hypertension 82053.
  • Key Recommendations

  • Utilize imaging modalities such as CT and MRI for definitive diagnosis of microcystic changes in renal tissue (Evidence: Moderate 1117).
  • Renal biopsy should be considered when clinical suspicion remains high despite imaging, to exclude other specific renal diseases (Evidence: Moderate 22).
  • Tailor management to address underlying causes and comorbidities, emphasizing control of hypertension and fluid status (Evidence: Expert opinion).
  • For vascular complications, consider endovascular interventions like embolization under appropriate clinical scenarios (Evidence: Moderate 44).
  • Monitor and manage medication errors carefully in renal patients due to altered pharmacokinetics (Evidence: Weak 57).
  • References

    Showing 100 most recent of 455 indexed papers.

    1 Cheun TJ, Davies MG. The Implications of Acute Anatomic Injury After Percutaneous Renal Intervention. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 2026. link 2 Skeik N, Theeler J, Wang J, Bae A, Cho M, Manunga J. Renal Artery Vasculopathy: Case Study and Literature Review. Angiology 2026. link 3 Tan H, Yu S. Use of Rituximab in Pediatric Nephrology: A Bibliometric and Visualization Analysis from 2003 to 2024. Critical reviews in eukaryotic gene expression 2025. link 4 Wang L, Jin X, Li Y. Characterizing Fenofibrate-Related Renal and Urinary Adverse Events: A Comprehensive Analysis of FDA Adverse Event Reporting System Database. Clinical therapeutics 2025. link 5 Červenka L, Husková Z, Kikerlová S, Gawrys O, Vacková Š, Škaroupková P et al.. Transgenic rat with ubiquitous expression of angiotensin-(1-7)-producing fusion protein: a new tool to study the role of protective arm of the renin-angiotensin system in the pathophysiology of cardio-renal diseases. Hypertension research : official journal of the Japanese Society of Hypertension 2025. link 6 Asai Y, Iwakura T, Ishigaki S, Isobe S, Fujikura T, Ohashi N et al.. Diagnostic Pitfalls of the Bleeding Origin after a Percutaneous Renal Biopsy. Internal medicine (Tokyo, Japan) 2025. link 7 Amador-Martínez I, Aranda-Rivera AK, Martínez-Castañeda MR, Pedraza-Chaverri J. Mitochondrial quality control and stress signaling pathways in the pathophysiology of cardio-renal diseases. Mitochondrion 2025. link 8 Bayes-Genis A, Cai A, Liu Y, Pandey A, Pop-Busui R, Hansen M et al.. Impact of canagliflozin on heart stress and outcomes: Pooled insights from CREDENCE and CANVAS. European journal of heart failure 2025. link 9 Hafez MH. Genomics Vision In Nephrology and Transplantation. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 2024. link 10 Wildes DM, Devlin C, Costigan CS, Raftery T, Hensey C, Waldron M et al.. Therapeutic plasma exchange in paediatric nephrology in Ireland. Irish journal of medical science 2024. link 11 Yasrab M, Fishman EK, Chu LC. Flank pain, hypertension, and hematuria: CT and 3D cinematic rendering in the evaluation of renal artery emergencies-a pictorial essay. Emergency radiology 2024. link 12 Comby PO, Guillen K, Chevallier O, Couloumy E, Dencausse A, Robert P et al.. Blocked-flow vs. free-flow cyanoacrylate glue embolization: Histological differences in an in vivo rabbit renal artery model. Diagnostic and interventional imaging 2024. link 13 Miura S, Katayama K, Joh K, Fujimoto M, Yamakawa M, Akiyama E et al.. Renal Medullary Angiitis Associated with Cutaneous Leukocytoclastic Vasculitis. Internal medicine (Tokyo, Japan) 2024. link 14 Aliu R, Jalo I, Olatoke L, Asabe I, Hassan KS, Bello A et al.. PATTERN OF RENAL DISEASES AMONG CHILDREN ATTENDING PAEDIATRIC NEPHROLOGY CLINIC, FEDERAL TEACHING HOSPITAL, GOMBE. West African journal of medicine 2023. link 15 Higuchi T, Hartrampf PE, Buck AK, Pomper MG, Rowe SP, Serfling SE et al.. Role of Functional SPECT and PET in Renal Emergencies. Seminars in nuclear medicine 2023. link 16 Xu N, Yang M, Liu J, Li X. Association of Vitamin D Receptor Genetic Polymorphisms With Nephrolithiasis and End-Stage Renal Disease: A Meta-Analysis. Transplantation proceedings 2022. link 17 Huynh AD, Sweet DE, Feldman MK, Remer EM. Imaging of renal emergencies: Review of infectious, hemorrhagic, vascular, and traumatic etiologies. The British journal of radiology 2022. link 18 Davies K, Bradley S, Crawford D. Biological basis of child health 15: understanding the renal system and common renal conditions in children. Nursing children and young people 2022. link 19 Bunbupha S, Apaijit K, Potue P, Maneesai P, Pakdeechote P. Hesperidin inhibits L-NAME-induced vascular and renal alterations in rats by suppressing the renin-angiotensin system, transforming growth factor-β1, and oxidative stress. Clinical and experimental pharmacology & physiology 2021. link 20 Patel RB, Ter Maaten JM, Ferreira JP, McCausland FR, Shah SJ, Rossignol P et al.. Challenges of Cardio-Kidney Composite Outcomes in Large-Scale Clinical Trials. Circulation 2021. link 21 Scope A, Schwendenwein I. Laboratory Evaluation of Renal Function in Birds. The veterinary clinics of North America. Exotic animal practice 2020. link 22 Sultanova RF, Schibalski R, Yankelevich IA, Stadler K, Ilatovskaya DV. Sex differences in renal mitochondrial function: a hormone-gous opportunity for research. American journal of physiology. Renal physiology 2020. link 23 Wilkinson SL, Divers SJ. Clinical Management of Reptile Renal Disease. The veterinary clinics of North America. Exotic animal practice 2020. link 24 Johnson JG, Watson MK. Diseases of the Reptile Renal System. The veterinary clinics of North America. Exotic animal practice 2020. link 25 DeFreitas MJ, Abitbol CL. Twin gestation and the burden of adult cardio-renal disease. Pediatric nephrology (Berlin, Germany) 2020. link 26 Kreuzer M, Drube J, Prüfe J, Schaefer F, Pape L. Current management of transition of young people affected by rare renal conditions in the ERKNet. European journal of human genetics : EJHG 2019. link 27 Rickard M, Hannick JH, Fernandez N, Koyle MA, MacMurdo K, Lorenzo AJ. Publication trends in pediatric renal transplantation: Bibliometric analysis of literature from 1950 to 2017. Pediatric transplantation 2019. link 28 Sun DZ, Abelson B, Babbar P, Damaser MS. Harnessing the mesenchymal stem cell secretome for regenerative urology. Nature reviews. Urology 2019. link 29 Kodama K, Takase Y, Tokai R, Saito K. Renal arteriovenous fistula induced by extracorporeal shock wave lithotripsy treated by retroperitoneoscopic nephrectomy. Asian journal of endoscopic surgery 2019. link 30 Langhorn R, Jessen LR, Kloster AS, Jensen AP, Koch J. Cardiac troponin I in cats with compromised renal function. Journal of feline medicine and surgery 2019. link 31 Nestor JG, Groopman EE, Gharavi AG. Towards precision nephrology: the opportunities and challenges of genomic medicine. Journal of nephrology 2018. link 32 Coulter CV. The role of the suspicious renal pharmacist in identifying unusual adverse drug reactions-why this is not a small problem. International journal of clinical pharmacy 2018. link 33 Fabrega-Foster KE, Agarwal S, Rastegar N, Haverstock D, Agris JM, Kamel IR. Efficacy and safety of gadobutrol-enhanced MRA of the renal arteries: Results from GRAMS (Gadobutrol-enhanced renal artery MRA study), a prospective, intraindividual multicenter phase 3 blinded study. Journal of magnetic resonance imaging : JMRI 2018. link 34 Teles P, Mendes M, Zankl M, de Sousa V, Santos AI, Vaz P. Assessment of the Absorbed Dose in the Kidney of Nuclear Nephrology Paediatric Patients using ICRP Biokinetic Data and Monte Carlo Simulations with Mass-Scaled Paediatric Voxel Phantoms. Radiation protection dosimetry 2017. link 35 Barisoni L, Hodgin JB. Digital pathology in nephrology clinical trials, research, and pathology practice. Current opinion in nephrology and hypertension 2017. link 36 Ferri C. The problem of cardio-renal diseases in patients with gout. Current medical research and opinion 2017. link 37 Ogbomo AS, Gronlund CJ, O'Neill MS, Konen T, Cameron L, Wahl R. Vulnerability to extreme-heat-associated hospitalization in three counties in Michigan, USA, 2000-2009. International journal of biometeorology 2017. link 38 Boudoulas KD, Triposkiadis F, Parissis J, Butler J, Boudoulas H. The Cardio-Renal Interrelationship. Progress in cardiovascular diseases 2017. link 39 Eknoyan G. Beginnings-The Kidney and Nephrology in Ancient Mesopotamian Culture. Seminars in dialysis 2016. link 40 Mydlík M, Derzsiová K. Associate Professor Eduard Neubauer: the first nephrologist in Slovak Republic. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 2016. link 41 Phillips ME, de Wardener S. Hugh de Wardener - the Man and the Scientist. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 2016. link 42 Fidan K, Isik Gonul I, Büyükkaragöz B, Isiyel E, Arinsoy T, Soylemezoglu O. Changing trends in pediatric renal biopsies: analysis of pediatric renal biopsies in national nephrology registry data. Renal failure 2016. link 43 Bayefsky SD, Shah HH, Jhaveri KD. Nephrology education for medical students: a narrative review. Renal failure 2016. link 44 Grenier N, Petitpierre F, Le Bras Y, Lasserre AS, Cornelis F. Renal embolization. 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Indications, technique, and outcome of therapeutic apheresis in European pediatric nephrology units. Pediatric nephrology (Berlin, Germany) 2015. link 50 Suson KD, Wolfe-Christensen C, Elder JS, Lakshmanan Y. National practice patterns and outcomes of pediatric nephrectomy: comparison between urology and general surgery. The Journal of urology 2015. link 51 Yim HE, Yoo KH, Bae IS, Hong YS, Lee JW. Differential modification of enalapril in the kidneys of lean and 'programmed' obese male young rats. Obesity research & clinical practice 2015. link 52 Muller A, Rouvière O. Renal artery embolization-indications, technical approaches and outcomes. Nature reviews. Nephrology 2015. link 53 Böhm M, Schumacher H, Schmieder RE, Mann JF, Teo K, Lonn E et al.. Resting heart rate is associated with renal disease outcomes in patients with vascular disease: results of the ONTARGET and TRANSCEND studies. Journal of internal medicine 2015. link 54 Lenarczyk M, Pressly JD, Arnett J, Regner KR, Park F. Localization and expression profile of Group I and II Activators of G-protein Signaling in the kidney. Journal of molecular histology 2015. link 55 Kurt B, Gerl K, Karger C, Schwarzensteiner I, Kurtz A. Chronic hypoxia-inducible transcription factor-2 activation stably transforms juxtaglomerular renin cells into fibroblast-like cells in vivo. Journal of the American Society of Nephrology : JASN 2015. link 56 Dutta S, Jaffer AK, Slawski BA, Pfeifer KJ, Smetana GW, Cohn SL. Perioperative anticoagulation and renal disease: an update. Hospital practice (1995) 2014. link 57 Gharekhani A, Kanani N, Khalili H, Dashti-Khavidaki S. Frequency, types, and direct related costs of medication errors in an academic nephrology ward in Iran. Renal failure 2014. link 58 Górriz JL, Gutiérrez F, Trullas JC, Arazo P, Arribas JR, Barril G et al.. Executive summary of the consensus document on the management of renal disease in HIV-infected patients. 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    Original source

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