Overview
Congenital viral hepatitis B infection refers to the transmission of the hepatitis B virus (HBV) from an infected mother to her infant during pregnancy, labor, or delivery. This can lead to chronic HBV infection in the child if not prevented.Diagnosis
Diagnosis of hepatitis B infection is typically made through serological testing, including tests for hepatitis B surface antigen (HBsAg), antibody to HBsAg (anti-HBs), and antibody to hepatitis B core antigen (anti-HBc) 1.Management
Management strategies for preventing congenital HBV infection include timely vaccination and administration of hepatitis B immune globulin (HBIG) to newborns born to infected mothers 1.Special Populations
Pregnancy: Pregnant individuals should be screened for hepatitis B infection to identify those who may transmit the virus to their infants 1.Key Recommendations
Screen pregnant individuals for hepatitis B infection to identify potential transmission risks to infants 1. (Evidence: Moderate)
Administer hepatitis B vaccination and hepatitis B immune globulin (HBIG) to newborns born to mothers with hepatitis B infection to prevent vertical transmission 1. (Evidence: Moderate)References
1 Tolera S, Mengistu DA, Alemu FK, Geremew A, Mulugeta Y, Dirirsa G et al.. Sero-prevalence of hepatitis viral infections among sanitary workers across worldwide: a systematic review and meta-analysis. BMC infectious diseases 2023. link