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Ophthalmology13 papers

Epidemic keratoconjunctivitis

Last edited: 4/15/2026

Overview

Epidemic keratoconjunctivitis (EKC) is a highly contagious viral infection primarily caused by adenoviruses, posing significant risks as healthcare-acquired infections (HAIs) in ophthalmology settings 1.

Diagnosis

  • Clinical presentation includes conjunctival hyperemia, watery discharge, and preauricular lymphadenopathy 1.
  • Exposure history to affected individuals or contaminated environments is crucial 1.
  • Laboratory confirmation via adenovirus detection through PCR or culture may be necessary 1.
  • Management

  • First-line treatments: Supportive care including artificial tears, cold compresses, and topical corticosteroids for inflammation (use cautiously to avoid side effects) 1.
  • Infection control measures: Strict adherence to universal precautions, including proper disinfection protocols for instruments (avoid using only 70% isopropyl alcohol; consider more effective disinfectants) 2.
  • Patient isolation: Implement isolation precautions to prevent spread, especially in clinical settings 1.
  • Special Populations

  • Healthcare settings: Enhanced infection control measures are critical to prevent HAIs in ophthalmology clinics 12.
  • No specific guidance provided for pregnancy, pediatrics, elderly, or comorbidities based on the given abstracts.
  • Key Recommendations

  • Implement standardized infection control protocols in ophthalmology clinics to prevent nosocomial EKC outbreaks (Evidence: Strong 1).
  • Use effective disinfectants other than 70% isopropyl alcohol for high-touch instruments like pneumotonometers to reduce viral transmission (Evidence: Moderate 2).
  • Enhance surveillance and reporting of EKC cases to promptly identify and manage outbreaks (Evidence: Expert opinion 1).
  • References

    1 Alai N. Enhancing best practices in ophthalmology for prevention of nosocomial epidemic keratoconjunctivitis infections. Current medical research and opinion 2016. link 2 Koo D, Bouvier B, Wesley M, Courtright P, Reingold A. Epidemic keratoconjunctivitis in a university medical center ophthalmology clinic; need for re-evaluation of the design and disinfection of instruments. Infection control and hospital epidemiology 1989. link 3 Hughes DE, Pugh GW. Infectious bovine keratoconjunctivitis: a ring device designed for prolonged retention in the bovine eye. American journal of veterinary research 1975. link

    Original source

    1. [1]
    2. [2]
      Epidemic keratoconjunctivitis in a university medical center ophthalmology clinic; need for re-evaluation of the design and disinfection of instruments.Koo D, Bouvier B, Wesley M, Courtright P, Reingold A Infection control and hospital epidemiology (1989)
    3. [3]
      Infectious bovine keratoconjunctivitis: a ring device designed for prolonged retention in the bovine eye.Hughes DE, Pugh GW American journal of veterinary research (1975)

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