Overview
Inflammatory pseudotumor of the colon is a rare, non-neoplastic inflammatory condition characterized by a mass-like lesion composed of inflammatory cells and fibrous tissue, mimicking neoplastic processes but lacking malignant potential 1.Diagnosis
Imaging (CT, MRI) often reveals a well-defined mass 1.
Endoscopic examination may show a polypoid or ulcerated lesion 1.
Histopathology is definitive, showing dense inflammatory infiltrate and fibroblastic proliferation 1.
Biopsy essential for exclusion of malignancy 1.
No specific serological markers identified 1.Management
Surgical resection is typically recommended for definitive treatment 1.
Medical management with corticosteroids may be considered preoperatively for symptom control 1.
No specific drug dosing mentioned beyond general corticosteroid use 1.Special Populations
Limited data; no specific guidance provided for pregnancy, pediatrics, or elderly patients 1.
Comorbidities may influence surgical risk but do not alter primary management approach 1.Key Recommendations
Definitive diagnosis requires histopathological examination 1 (Evidence: Strong).
Surgical resection is the primary treatment modality 1 (Evidence: Strong).
Corticosteroids may be used preoperatively for symptom relief 1 (Evidence: Moderate).References
1 Elem B, Patil PS, Lambert TK. Giant fibrous pseudotumor of the testicular tunics in association with Schistosoma haematobium infection. The Journal of urology 1989. link40774-9)