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Cardiology4 papers

Infection by Strongylus

Last edited: 4/22/2026

Overview

Strongylus vulgaris is a gastrointestinal nematode that causes significant pathology in equines, particularly affecting the arterial system leading to verminous arteritis characterized by thrombi formation and arterial wall damage 2.

Diagnosis

  • Clinical signs include colic, weight loss, and potentially acute verminous arteritis with specific lesions at necropsy.
  • Necropsy findings reveal arterial larval burdens and characteristic lesions such as arterial wall thickening and thrombi formation 2.
  • Histopathological examination of affected arteries can confirm the presence of larvae and associated inflammatory changes 2.
  • Management

  • First-line Treatment: Regular anthelmintic treatment with ivermectin (frequency and dose not specified in abstracts) to reduce larval burdens 1.
  • Vaccination: Foalhood vaccination with irradiation-attenuated L3 larvae vaccine can significantly reduce arterial larval burdens and clinical signs in yearlings when challenged with S. vulgaris 1.
  • Environmental Control: Pasture management to minimize exposure to infective larvae stages is crucial but not detailed in the abstracts.
  • Special Populations

  • Pediatrics: Foalhood vaccination appears effective in reducing the impact of Strongylus vulgaris infection in young equines 1.
  • Key Recommendations

  • Implement regular anthelmintic treatment, particularly with ivermectin, to control Strongylus vulgaris burdens in all equines 1. (Evidence: Strong)
  • Consider foalhood vaccination with irradiation-attenuated L3 larvae vaccine to protect against severe arterial infection in yearlings 1. (Evidence: Moderate)
  • Monitor and manage pasture conditions to reduce environmental exposure to infective larvae stages, though specific protocols are not detailed in the provided abstracts 1. (Evidence: Expert opinion)
  • References

    1 Klei TR, French DD, Chapman MR, McClure JR, Dennis VA, Taylor HW et al.. Protection of yearling ponies against Strongylus vulgaris by foalhood vaccination. Equine veterinary journal. Supplement 1989. link 2 White NA, Moore JN, Douglas M. SEM study of Strongylus vulgaris larva-induced arteritis in the pony. Equine veterinary journal 1983. link

    Original source

    1. [1]
      Protection of yearling ponies against Strongylus vulgaris by foalhood vaccination.Klei TR, French DD, Chapman MR, McClure JR, Dennis VA, Taylor HW et al. Equine veterinary journal. Supplement (1989)
    2. [2]
      SEM study of Strongylus vulgaris larva-induced arteritis in the pony.White NA, Moore JN, Douglas M Equine veterinary journal (1983)

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