Overview
Meigs' syndrome is a rare condition characterized by the triad of a benign ovarian tumor, ascites, and pleural effusion, often initially misdiagnosed as malignant pleural or peritoneal dissemination 1.Diagnosis
Clinical Presentation: Benign ovarian tumor, ascites, and pleural effusion 1.
Diagnostic Tests:
- Thoracentesis revealing serosanguineous exudative effusion 1.
- Imaging (CT, MRI) to rule out malignant dissemination 1.
Differential Diagnosis: Distinguishing from heart failure with preserved ejection fraction and malignant pleural/peritoneal spread 1.Management
Surgical Intervention: Removal of the ovarian tumor as definitive treatment 1.
Supportive Care: Management of pleural effusion and ascites, often requiring thoracentesis and paracentesis 1.
Monitoring: Repeated imaging and fluid analysis to ensure resolution of effusions post-surgery 1.Special Populations
Elderly: Presentation can mimic heart failure, necessitating careful differentiation 1.Key Recommendations
Confirm Diagnosis Through Thoracentesis and Imaging: Essential to differentiate from malignant conditions (Evidence: Weak 1).
Surgical Removal of Ovarian Tumor: Primary treatment to resolve associated effusions (Evidence: Expert opinion 1).
Monitor Effusions Post-Surgery: Regular follow-up imaging and fluid analysis to ensure complete resolution (Evidence: Expert opinion 1).References
1 Murayama Y, Kamoi Y, Yamamoto H, Isogai J, Tanaka T. Meigs' syndrome mimicking heart failure with preserved ejection fraction: a case report. BMC cardiovascular disorders 2020. link