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Mycoplasma mastitis

Last edited: 4/15/2026

Overview

Mycoplasma mastitis is a form of mastitis caused by Mycoplasma species, leading to inflammation of the mammary gland in lactating animals, particularly cows. It often presents with subclinical symptoms but can result in significant economic losses due to reduced milk quality and quantity 2.

Diagnosis

  • Culture and PCR: Recommended for definitive diagnosis, detecting Mycoplasma species directly from milk samples 2.
  • Clinical Signs: Monitoring for decreased milk yield, changes in milk composition, and udder inflammation 2.
  • Ultramicrochemical Tests: Not typically used for mastitis diagnosis but highlight the importance of sensitive detection methods for mycoplasmas 2.
  • Management

  • Antibiotics: Tylosin or other macrolides are commonly used; specific dosing varies but often includes prolonged treatment courses 2.
  • Supportive Care: Ensuring proper udder hygiene and milking practices to prevent recurrence 2.
  • Monitoring: Regular milk quality checks and clinical monitoring of affected animals 2.
  • Special Populations

  • No Specific Data: The provided abstracts do not cover special populations such as pregnancy, pediatrics, elderly, or comorbidities related to Mycoplasma mastitis 12.
  • Key Recommendations

  • Utilize culture and PCR methods for accurate diagnosis of Mycoplasma mastitis (Evidence: Moderate) 2.
  • Implement prolonged antibiotic therapy, typically with macrolides like tylosin, for effective treatment (Evidence: Expert opinion) 2.
  • Maintain stringent udder hygiene and milking protocols to prevent and control Mycoplasma mastitis outbreaks (Evidence: Expert opinion) 2.
  • References

    1 Heitmann J, Kirchhoff H, Chercheletzi C, Jonas E, Deegen E. Isolation of acholeplasmas from horse feces. Veterinary microbiology 1982. link90040-2) 2 Uitendaal MP, DeBruyn CH, Hatanaka M, Hösli P. An ultramicrochemical test for mycoplasmal contamination of cultured cells. In vitro 1979. link

    Original source

    1. [1]
      Isolation of acholeplasmas from horse feces.Heitmann J, Kirchhoff H, Chercheletzi C, Jonas E, Deegen E Veterinary microbiology (1982)
    2. [2]
      An ultramicrochemical test for mycoplasmal contamination of cultured cells.Uitendaal MP, DeBruyn CH, Hatanaka M, Hösli P In vitro (1979)

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